NO319386B1 - Sammensetninger inneholdende vismut og ett eller flere antimikrobielle midler for forebygging og behandling av gastrointestinale forstyrrelser - Google Patents
Sammensetninger inneholdende vismut og ett eller flere antimikrobielle midler for forebygging og behandling av gastrointestinale forstyrrelser Download PDFInfo
- Publication number
- NO319386B1 NO319386B1 NO19982635A NO982635A NO319386B1 NO 319386 B1 NO319386 B1 NO 319386B1 NO 19982635 A NO19982635 A NO 19982635A NO 982635 A NO982635 A NO 982635A NO 319386 B1 NO319386 B1 NO 319386B1
- Authority
- NO
- Norway
- Prior art keywords
- bismuth
- days
- administered
- antimicrobial agents
- per day
- Prior art date
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- 206010025482 malaise Diseases 0.000 description 1
- 229960005329 mefloquine hydrochloride Drugs 0.000 description 1
- 229960000901 mepacrine Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 229960004918 nimorazole Drugs 0.000 description 1
- MDJFHRLTPRPZLY-UHFFFAOYSA-N nimorazole Chemical compound [O-][N+](=O)C1=CN=CN1CCN1CCOCC1 MDJFHRLTPRPZLY-UHFFFAOYSA-N 0.000 description 1
- 229960001180 norfloxacin Drugs 0.000 description 1
- OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 1
- 238000001668 nucleic acid synthesis Methods 0.000 description 1
- 229960001699 ofloxacin Drugs 0.000 description 1
- 229960000625 oxytetracycline Drugs 0.000 description 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 1
- 235000019366 oxytetracycline Nutrition 0.000 description 1
- 229940056360 penicillin g Drugs 0.000 description 1
- 229940056367 penicillin v Drugs 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 230000004260 plant-type cell wall biogenesis Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- GPKJTRJOBQGKQK-UHFFFAOYSA-N quinacrine Chemical compound C1=C(OC)C=C2C(NC(C)CCCN(CC)CC)=C(C=CC(Cl)=C3)C3=NC2=C1 GPKJTRJOBQGKQK-UHFFFAOYSA-N 0.000 description 1
- 150000007660 quinolones Chemical class 0.000 description 1
- 229960001225 rifampicin Drugs 0.000 description 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960005404 sulfamethoxazole Drugs 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/245—Bismuth; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/569,029 US5744168A (en) | 1995-12-07 | 1995-12-07 | Methods and compositions for the prevention and treatment of gastrointestinal disorders |
| PCT/US1996/018652 WO1997020565A1 (en) | 1995-12-07 | 1996-11-22 | Compositions, containing bismuth and one or more antimicrobials, for the prevention and treatment of gastrointestinal disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO982635D0 NO982635D0 (no) | 1998-06-08 |
| NO982635L NO982635L (no) | 1998-08-04 |
| NO319386B1 true NO319386B1 (no) | 2005-08-08 |
Family
ID=24273803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19982635A NO319386B1 (no) | 1995-12-07 | 1998-06-08 | Sammensetninger inneholdende vismut og ett eller flere antimikrobielle midler for forebygging og behandling av gastrointestinale forstyrrelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5744168A (pt) |
| EP (1) | EP0865284B1 (pt) |
| AT (1) | ATE231726T1 (pt) |
| BR (1) | BR9612123A (pt) |
| CA (1) | CA2239423C (pt) |
| CO (1) | CO4940459A1 (pt) |
| DE (1) | DE69626036T2 (pt) |
| DK (1) | DK0865284T3 (pt) |
| ES (1) | ES2191776T3 (pt) |
| IL (1) | IL124792A (pt) |
| MX (1) | MX9804577A (pt) |
| MY (1) | MY113635A (pt) |
| NO (1) | NO319386B1 (pt) |
| PT (1) | PT865284E (pt) |
| TR (1) | TR199801024T2 (pt) |
| TW (1) | TW445143B (pt) |
| WO (1) | WO1997020565A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9224739D0 (en) * | 1992-11-26 | 1993-01-13 | Wellcome Found | Medicaments |
| ATE469639T1 (de) * | 2001-08-08 | 2010-06-15 | Dominguez Maria Antonia Garcia-Olmedo | Injizierbarer schaum und neue pharmazeutische anwendungen dafür |
| FR2962684B1 (fr) | 2010-07-13 | 2012-08-24 | Oberthur Technologies | Procede de realisation d'un motif sur un support avec une encre de securite |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR962163A (pt) * | 1950-06-02 | |||
| US4049817A (en) * | 1972-08-14 | 1977-09-20 | Sandoz Ltd. | Synergistic compositions |
| US4514421A (en) * | 1979-08-30 | 1985-04-30 | Herschler R J | Dietary and pharmaceutical uses of methylsulfonylmethane and compositions comprising it |
| EP0222834A4 (en) * | 1985-04-18 | 1989-10-04 | Borody Thomas J | TREATMENT OF NON-ULCERATIVE DYSPEPSIA WITH BISMUTOUS SALTS. |
| EP0462631B1 (en) * | 1985-06-13 | 1996-03-20 | Barry James Dr. Marshall | Methods and compositions for the treatment of gastrointestinal disorders |
| US5256684A (en) * | 1985-06-13 | 1993-10-26 | The Procter & Gamble Company | Methods and compositions for the treatment of gastrointestinal disorders |
| JPS63174926A (ja) * | 1987-01-09 | 1988-07-19 | Nitto Kasei Kk | 家禽用抗コクシジウム剤 |
| IL85472A (en) * | 1987-03-09 | 1991-06-30 | Procter & Gamble | Pharmaceutical compositions for treating gastrointestinal disorders |
| WO1989003219A1 (en) * | 1987-10-12 | 1989-04-20 | Borody Thomas J | Improved method for treatment of gastrointestinal disorders |
| EP0375068A1 (en) * | 1988-12-23 | 1990-06-27 | Gist-Brocades N.V. | Combining bismuth compounds and tetracyclines |
| US5221664A (en) * | 1990-04-23 | 1993-06-22 | Magainin Pharmaaceuticals Inc. | Composition and treatment with biologically active peptides and toxic cations |
| DE69117955T2 (de) * | 1990-07-20 | 1996-09-19 | Tillotts Pharma Ag, Ziefen | Produkte und verfahren zur behandlung des verdauungskanals |
| DE59309771D1 (de) * | 1993-05-11 | 1999-10-14 | Spirig Ag | Festes bismut- und amoxycillinhaltiges Arzneipräparat und seine Verwendung |
| AUPM596894A0 (en) * | 1994-05-30 | 1994-06-23 | Hybrid Scientific Pty Ltd | Composition for treating gastrointestinal disorders - a combination of bismuth salts plus lactobacillus or bifidobacteria species bacteria for treating gastrointestinal disorders |
-
1995
- 1995-12-07 US US08/569,029 patent/US5744168A/en not_active Expired - Fee Related
-
1996
- 1996-11-22 WO PCT/US1996/018652 patent/WO1997020565A1/en active IP Right Grant
- 1996-11-22 DE DE69626036T patent/DE69626036T2/de not_active Expired - Fee Related
- 1996-11-22 ES ES96940568T patent/ES2191776T3/es not_active Expired - Lifetime
- 1996-11-22 EP EP96940568A patent/EP0865284B1/en not_active Expired - Lifetime
- 1996-11-22 PT PT96940568T patent/PT865284E/pt unknown
- 1996-11-22 CA CA002239423A patent/CA2239423C/en not_active Expired - Fee Related
- 1996-11-22 TR TR1998/01024T patent/TR199801024T2/xx unknown
- 1996-11-22 AT AT96940568T patent/ATE231726T1/de not_active IP Right Cessation
- 1996-11-22 IL IL12479296A patent/IL124792A/en not_active IP Right Cessation
- 1996-11-22 DK DK96940568T patent/DK0865284T3/da active
- 1996-11-22 BR BR9612123A patent/BR9612123A/pt not_active Application Discontinuation
- 1996-12-04 CO CO96063581A patent/CO4940459A1/es unknown
- 1996-12-07 MY MYPI96005154A patent/MY113635A/en unknown
- 1996-12-26 TW TW085116051A patent/TW445143B/zh active
-
1998
- 1998-06-08 NO NO19982635A patent/NO319386B1/no unknown
- 1998-06-08 MX MX9804577A patent/MX9804577A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997020565A1 (en) | 1997-06-12 |
| TW445143B (en) | 2001-07-11 |
| DE69626036D1 (de) | 2003-03-06 |
| PT865284E (pt) | 2003-06-30 |
| CO4940459A1 (es) | 2000-07-24 |
| DK0865284T3 (da) | 2003-05-19 |
| NO982635L (no) | 1998-08-04 |
| ES2191776T3 (es) | 2003-09-16 |
| NO982635D0 (no) | 1998-06-08 |
| BR9612123A (pt) | 1999-02-17 |
| IL124792A0 (en) | 1999-01-26 |
| DE69626036T2 (de) | 2004-01-22 |
| IL124792A (en) | 2004-01-04 |
| US5744168A (en) | 1998-04-28 |
| TR199801024T2 (xx) | 1998-09-21 |
| CA2239423C (en) | 2003-04-01 |
| ATE231726T1 (de) | 2003-02-15 |
| MY113635A (en) | 2002-04-30 |
| EP0865284A1 (en) | 1998-09-23 |
| MX9804577A (es) | 1998-10-31 |
| CA2239423A1 (en) | 1997-06-12 |
| EP0865284B1 (en) | 2003-01-29 |
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