NO317919B1 - Tri-, tetra-, penta-, og polypeptider samt deres anvendelse for fremstilling av et farmasoytisk preparat til behandling av depresjon - Google Patents

Tri-, tetra-, penta-, og polypeptider samt deres anvendelse for fremstilling av et farmasoytisk preparat til behandling av depresjon Download PDF

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Publication number
NO317919B1
NO317919B1 NO19964561A NO964561A NO317919B1 NO 317919 B1 NO317919 B1 NO 317919B1 NO 19964561 A NO19964561 A NO 19964561A NO 964561 A NO964561 A NO 964561A NO 317919 B1 NO317919 B1 NO 317919B1
Authority
NO
Norway
Prior art keywords
pro
group
gly
trp
accordance
Prior art date
Application number
NO19964561A
Other languages
English (en)
Norwegian (no)
Other versions
NO964561D0 (no
NO964561L (no
Inventor
Joseph John Hlavka
Henry B Abajian
John F Noble
Original Assignee
Innapharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innapharma Inc filed Critical Innapharma Inc
Publication of NO964561D0 publication Critical patent/NO964561D0/no
Publication of NO964561L publication Critical patent/NO964561L/no
Publication of NO317919B1 publication Critical patent/NO317919B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1027Tetrapeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19964561A 1994-05-04 1996-10-28 Tri-, tetra-, penta-, og polypeptider samt deres anvendelse for fremstilling av et farmasoytisk preparat til behandling av depresjon NO317919B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/238,089 US5589460A (en) 1994-05-04 1994-05-04 Tri-, tetra-, penta-, and polypeptides and their therapeutic use as an antidepressant agent
PCT/US1995/005560 WO1995030430A1 (en) 1994-05-04 1995-05-02 Tri-, tetra-, penta-, and polypeptides and their therapeutic use as an antidepressant agent

Publications (3)

Publication Number Publication Date
NO964561D0 NO964561D0 (no) 1996-10-28
NO964561L NO964561L (no) 1996-12-27
NO317919B1 true NO317919B1 (no) 2005-01-03

Family

ID=22896449

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964561A NO317919B1 (no) 1994-05-04 1996-10-28 Tri-, tetra-, penta-, og polypeptider samt deres anvendelse for fremstilling av et farmasoytisk preparat til behandling av depresjon

Country Status (16)

Country Link
US (1) US5589460A (ru)
EP (1) EP0759772B1 (ru)
JP (1) JP3878983B2 (ru)
CN (1) CN1150028C (ru)
AT (1) ATE258061T1 (ru)
AU (1) AU685292B2 (ru)
CA (1) CA2189145C (ru)
DE (1) DE69532470T2 (ru)
DK (1) DK0759772T3 (ru)
ES (1) ES2215175T3 (ru)
FI (1) FI964363A (ru)
MY (1) MY113407A (ru)
NO (1) NO317919B1 (ru)
PT (1) PT759772E (ru)
RU (1) RU2182910C2 (ru)
WO (1) WO1995030430A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6767897B2 (en) * 1994-05-04 2004-07-27 Innapharma, Inc. Therapeutic uses of tri-, tetra-, penta-, and polypeptides
US6093797A (en) * 1994-05-04 2000-07-25 Innapharma, Inc. Tri-, Tetra-, Penta-, and polypeptides and their therapeutic use as an antidepressant agent
US5767083A (en) * 1994-05-04 1998-06-16 Innapharma, Inc. Tri-, tetra-, penta-, and polypeptides and their therapeutic use as an antidepressant agent
US5792466A (en) * 1996-12-13 1998-08-11 The United States Of America, As Represented By The Secretary Of Agriculture Mimetic insect kinin analogs for insect control
AU8912698A (en) * 1997-08-19 1999-03-08 University Of Medicine And Dentistry Of New Jersey Inhibition of hiv-1 replication using d-amino acid peptides
US6150420A (en) * 1998-06-01 2000-11-21 Theramax, Inc. Method for enhanced brain delivery of bupropion
EP1741719B1 (en) * 2004-03-31 2015-02-25 Patent Technology Development Inc. Epithelial cell growth promoter
WO2009003034A1 (en) * 2007-06-27 2008-12-31 The Board Of Trustees Of The Leland Stanford Junior University Oligopeptide tyrosinase inhibitors and uses thereof
CA2728140C (en) * 2007-06-27 2019-09-03 The Board Of Trustees Of The Leland Stanford Junior University Peptide tyrosinase inhibitors and uses thereof
CN101284868A (zh) * 2008-05-26 2008-10-15 刘刚 一种肽水合盐类化合物及其立体异构体
CN108690121B (zh) * 2017-04-07 2020-05-15 深圳翰宇药业股份有限公司 一种奈米非肽液相制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3708593A (en) * 1971-08-24 1973-01-02 Abbott Lab Use of l-prolyl l-leucyl glycine amide as an anti-depressant
US3821188A (en) * 1972-06-14 1974-06-28 American Home Prod Proline and pyroglutamic acid containing tripeptides
US3795738A (en) * 1972-12-26 1974-03-05 Abbott Lab Use of l-propyl l-leucyl glycine amide to treat parkinson's disease
US3931184A (en) * 1974-10-31 1976-01-06 Abbott Laboratories Purification method for prolyl-leucylglycinamide
US4018912A (en) * 1975-07-28 1977-04-19 Ayerst Mckenna And Harrison Ltd. Tripeptide derivatives with central nervous system activity and preparation thereof
US4278595A (en) * 1979-12-10 1981-07-14 Vega Laboratories, Inc. Orally active MIF analogs with an effect on the central nervous system
JPS5830299B2 (ja) * 1981-10-30 1983-06-28 三菱化学株式会社 トリペプチドおよびその誘導体
DE3226241A1 (de) * 1982-07-14 1984-01-26 Basf Ag, 6700 Ludwigshafen N-acylderivate von peptiden, ihre herstellung und verwendung bei der bekaempfung von krankheiten und mittel dafuer
JP3349528B2 (ja) * 1992-08-14 2002-11-25 株式会社日清製粉グループ本社 ペプチド

Also Published As

Publication number Publication date
AU2813995A (en) 1995-11-29
ES2215175T3 (es) 2004-10-01
PT759772E (pt) 2004-06-30
FI964363A (fi) 1996-12-23
NO964561D0 (no) 1996-10-28
EP0759772B1 (en) 2004-01-21
US5589460A (en) 1996-12-31
NO964561L (no) 1996-12-27
RU2182910C2 (ru) 2002-05-27
JP3878983B2 (ja) 2007-02-07
CA2189145A1 (en) 1995-11-16
MY113407A (en) 2002-02-28
DE69532470T2 (de) 2004-10-21
DK0759772T3 (da) 2004-06-01
EP0759772A4 (en) 1999-04-21
CA2189145C (en) 2008-03-18
CN1151700A (zh) 1997-06-11
WO1995030430A1 (en) 1995-11-16
DE69532470D1 (de) 2004-02-26
JPH10500407A (ja) 1998-01-13
AU685292B2 (en) 1998-01-15
ATE258061T1 (de) 2004-02-15
CN1150028C (zh) 2004-05-19
EP0759772A1 (en) 1997-03-05
FI964363A0 (fi) 1996-10-29

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FC2A Withdrawal, rejection or dismissal of laid open patent application
RE Reestablishment of rights (par. 72 patents act)