NO317136B1 - Antikonvulsivt virkende derivater til bruk ved behandling av amyotrofisk lateral sklerose (ALS) - Google Patents
Antikonvulsivt virkende derivater til bruk ved behandling av amyotrofisk lateral sklerose (ALS) Download PDFInfo
- Publication number
- NO317136B1 NO317136B1 NO19986054A NO986054A NO317136B1 NO 317136 B1 NO317136 B1 NO 317136B1 NO 19986054 A NO19986054 A NO 19986054A NO 986054 A NO986054 A NO 986054A NO 317136 B1 NO317136 B1 NO 317136B1
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- Prior art keywords
- formula
- topiramate
- alkyl
- als
- kainate
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Classifications
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2200696P | 1996-06-28 | 1996-06-28 | |
| PCT/US1997/010955 WO1998000131A1 (en) | 1996-06-28 | 1997-06-24 | Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (als) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO986054D0 NO986054D0 (no) | 1998-12-22 |
| NO986054L NO986054L (no) | 1999-03-01 |
| NO317136B1 true NO317136B1 (no) | 2004-08-23 |
Family
ID=21807346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19986054A NO317136B1 (no) | 1996-06-28 | 1998-12-22 | Antikonvulsivt virkende derivater til bruk ved behandling av amyotrofisk lateral sklerose (ALS) |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5753694A (es) |
| EP (1) | EP0936908B1 (es) |
| JP (1) | JP2000514426A (es) |
| AP (1) | AP1167A (es) |
| AT (1) | ATE214274T1 (es) |
| AU (1) | AU725093B2 (es) |
| BR (1) | BR9710993A (es) |
| CA (1) | CA2258892C (es) |
| CZ (1) | CZ293945B6 (es) |
| DE (1) | DE69711067T2 (es) |
| DK (1) | DK0936908T3 (es) |
| ES (1) | ES2176755T3 (es) |
| HU (1) | HUP9904318A3 (es) |
| IL (1) | IL127717A (es) |
| NO (1) | NO317136B1 (es) |
| NZ (1) | NZ333588A (es) |
| PT (1) | PT936908E (es) |
| SI (1) | SI0936908T1 (es) |
| SK (1) | SK284331B6 (es) |
| UA (1) | UA46112C2 (es) |
| WO (1) | WO1998000131A1 (es) |
| ZA (1) | ZA975764B (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985930A (en) * | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
| CA2369095C (en) | 1999-04-08 | 2006-07-25 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
| US20080255093A1 (en) * | 1999-06-14 | 2008-10-16 | Tam Peter Y | Compositions and methods for treating obesity and related disorders |
| DK1187603T3 (da) | 1999-06-14 | 2007-12-17 | Vivus Inc | Kombinationsterapi tl at bevirke vægttab og at behandle obesitet |
| US20080103179A1 (en) * | 2006-10-27 | 2008-05-01 | Tam Peter Y | Combination Therapy |
| US7553818B2 (en) * | 1999-06-14 | 2009-06-30 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US7056890B2 (en) | 1999-06-14 | 2006-06-06 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US7674776B2 (en) | 1999-06-14 | 2010-03-09 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US7659256B2 (en) * | 1999-06-14 | 2010-02-09 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US6191117B1 (en) * | 2000-07-10 | 2001-02-20 | Walter E. Kozachuk | Methods of producing weight loss and treatment of obesity |
| US20020082222A1 (en) | 2000-11-30 | 2002-06-27 | Shapira Nathan Andrew | Treatments for neurogenetic disorders, impulse control disorder, and wound healing |
| ATE361089T1 (de) | 2001-02-02 | 2007-05-15 | Ortho Mcneil Pharm Inc | Behandlung von neurologischen funktionsstörungen mit fructopyranosesulfamaten und erythropoetin |
| US20030144347A1 (en) * | 2001-11-14 | 2003-07-31 | Ralph Ryback | Method for treating autoimmune disease |
| WO2004043444A1 (en) * | 2002-11-06 | 2004-05-27 | Mount Sinai School Of Medicine | Treatment of amyotrophic lateral sclerosis with nimesulide |
| US20060041022A1 (en) * | 2002-11-06 | 2006-02-23 | Pasinetti Giulio M | Treatment of amyotrophic lateral sclerosis with nimesulide |
| US20050070524A1 (en) * | 2003-06-06 | 2005-03-31 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| AR049646A1 (es) * | 2004-06-16 | 2006-08-23 | Janssen Pharmaceutica Nv | Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados |
| ES2310366T3 (es) * | 2004-08-24 | 2009-01-01 | Janssen Pharmaceutica Nv | Nuevos derivados de heteroaril sulfonamida benzo-condensada utiles como agentes anticonvulsivos. |
| IS7748A (is) * | 2005-03-17 | 2006-09-18 | Actavis Group | Samsetning fyrir töflur sem innihalda topiramate |
| AU2006249577A1 (en) * | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
| AR058389A1 (es) * | 2005-12-19 | 2008-01-30 | Janssen Pharmaceutica Nv | Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad |
| US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
| US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
| US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
| US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
| US20070191460A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Disease Modification / Epileptogenesis |
| US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
| US20070191451A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives as neuroprotective agents |
| AU2007253814A1 (en) * | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
| FR2903019A1 (fr) * | 2006-06-30 | 2008-01-04 | Univ Claude Bernard Lyon I Eta | Utilisation d'un inhibiteur de l'anhydrase carbonique, pour la preparation d'un medicament destine a traiter des degenerescences du muscle squelettique |
| US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| US8580298B2 (en) | 2008-06-09 | 2013-11-12 | Vivus, Inc. | Low dose topiramate/phentermine composition and methods of use thereof |
| US20090304789A1 (en) | 2008-06-09 | 2009-12-10 | Thomas Najarian | Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders |
| NZ590682A (en) | 2008-06-23 | 2012-09-28 | Janssen Pharmaceutica Nv | Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| US4792569A (en) * | 1987-08-27 | 1988-12-20 | Mcneilab, Inc. | Anticonvulsant phenethyl sulfamates |
| US5384327A (en) * | 1992-12-22 | 1995-01-24 | Mcneilab, Inc. | Anticonvulsant sorbopyranose sulfamates |
-
1997
- 1997-06-23 US US08/881,023 patent/US5753694A/en not_active Expired - Fee Related
- 1997-06-24 HU HU9904318A patent/HUP9904318A3/hu unknown
- 1997-06-24 ES ES97931367T patent/ES2176755T3/es not_active Expired - Lifetime
- 1997-06-24 AU AU35010/97A patent/AU725093B2/en not_active Ceased
- 1997-06-24 BR BR9710993-2A patent/BR9710993A/pt not_active Application Discontinuation
- 1997-06-24 CA CA002258892A patent/CA2258892C/en not_active Expired - Fee Related
- 1997-06-24 PT PT97931367T patent/PT936908E/pt unknown
- 1997-06-24 AT AT97931367T patent/ATE214274T1/de not_active IP Right Cessation
- 1997-06-24 DE DE69711067T patent/DE69711067T2/de not_active Expired - Fee Related
- 1997-06-24 UA UA98126945A patent/UA46112C2/uk unknown
- 1997-06-24 WO PCT/US1997/010955 patent/WO1998000131A1/en active IP Right Grant
- 1997-06-24 NZ NZ333588A patent/NZ333588A/xx unknown
- 1997-06-24 IL IL12771797A patent/IL127717A/en not_active IP Right Cessation
- 1997-06-24 CZ CZ19984279A patent/CZ293945B6/cs not_active IP Right Cessation
- 1997-06-24 SI SI9730259T patent/SI0936908T1/xx unknown
- 1997-06-24 SK SK1806-98A patent/SK284331B6/sk unknown
- 1997-06-24 DK DK97931367T patent/DK0936908T3/da active
- 1997-06-24 AP APAP/P/1998/001428A patent/AP1167A/en active
- 1997-06-24 EP EP97931367A patent/EP0936908B1/en not_active Expired - Lifetime
- 1997-06-24 JP JP10504245A patent/JP2000514426A/ja active Pending
- 1997-06-27 ZA ZA975764A patent/ZA975764B/xx unknown
-
1998
- 1998-12-22 NO NO19986054A patent/NO317136B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998000131A1 (en) | 1998-01-08 |
| SK180698A3 (en) | 2000-07-11 |
| NZ333588A (en) | 2000-07-28 |
| JP2000514426A (ja) | 2000-10-31 |
| CA2258892A1 (en) | 1998-01-08 |
| EP0936908A1 (en) | 1999-08-25 |
| AU725093B2 (en) | 2000-10-05 |
| AP9801428A0 (en) | 1998-12-31 |
| CZ293945B6 (cs) | 2004-08-18 |
| AU3501097A (en) | 1998-01-21 |
| CZ427998A3 (cs) | 1999-08-11 |
| CA2258892C (en) | 2005-08-09 |
| NO986054L (no) | 1999-03-01 |
| IL127717A (en) | 2004-09-27 |
| BR9710993A (pt) | 2002-02-26 |
| PT936908E (pt) | 2002-08-30 |
| AP1167A (en) | 2003-06-30 |
| UA46112C2 (uk) | 2002-05-15 |
| SK284331B6 (sk) | 2005-01-03 |
| DK0936908T3 (da) | 2002-05-27 |
| HUP9904318A2 (hu) | 2000-05-28 |
| DE69711067D1 (de) | 2002-04-18 |
| DE69711067T2 (de) | 2002-09-19 |
| SI0936908T1 (en) | 2002-12-31 |
| EP0936908B1 (en) | 2002-03-13 |
| HUP9904318A3 (en) | 2001-02-28 |
| ZA975764B (en) | 1998-12-28 |
| ES2176755T3 (es) | 2002-12-01 |
| NO986054D0 (no) | 1998-12-22 |
| IL127717A0 (en) | 1999-10-28 |
| ATE214274T1 (de) | 2002-03-15 |
| US5753694A (en) | 1998-05-19 |
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