NO310656B1 - Hemoregulatoriske forbindelser - Google Patents
Hemoregulatoriske forbindelser Download PDFInfo
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- NO310656B1 NO310656B1 NO19982151A NO982151A NO310656B1 NO 310656 B1 NO310656 B1 NO 310656B1 NO 19982151 A NO19982151 A NO 19982151A NO 982151 A NO982151 A NO 982151A NO 310656 B1 NO310656 B1 NO 310656B1
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- 229910052791 calcium Inorganic materials 0.000 description 1
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- PASHVRUKOFIRIK-UHFFFAOYSA-L calcium sulfate dihydrate Chemical compound O.O.[Ca+2].[O-]S([O-])(=O)=O PASHVRUKOFIRIK-UHFFFAOYSA-L 0.000 description 1
- 201000003984 candidiasis Diseases 0.000 description 1
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- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000022131 cell cycle Effects 0.000 description 1
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- 235000019868 cocoa butter Nutrition 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 239000012230 colorless oil Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
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- 239000013078 crystal Substances 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 238000011393 cytotoxic chemotherapy Methods 0.000 description 1
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- 239000008121 dextrose Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
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- 231100000371 dose-limiting toxicity Toxicity 0.000 description 1
- 210000003979 eosinophil Anatomy 0.000 description 1
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- 239000002024 ethyl acetate extract Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
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- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229940074045 glyceryl distearate Drugs 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 208000024908 graft versus host disease Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
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- 210000000777 hematopoietic system Anatomy 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
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- 230000001506 immunosuppresive effect Effects 0.000 description 1
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- 230000002458 infectious effect Effects 0.000 description 1
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- 239000007924 injection Substances 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 239000008176 lyophilized powder Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 229940071648 metered dose inhaler Drugs 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
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- 239000007922 nasal spray Substances 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 210000000440 neutrophil Anatomy 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 210000002997 osteoclast Anatomy 0.000 description 1
- BZWZQQPETNQTFG-UHFFFAOYSA-N oxane-4,4-dicarbonitrile Chemical compound N#CC1(C#N)CCOCC1 BZWZQQPETNQTFG-UHFFFAOYSA-N 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000009520 phase I clinical trial Methods 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- BEOOHQFXGBMRKU-UHFFFAOYSA-N sodium cyanoborohydride Chemical compound [Na+].[B-]C#N BEOOHQFXGBMRKU-UHFFFAOYSA-N 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000012258 stirred mixture Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000759 toxicological effect Toxicity 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
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- 238000005406 washing Methods 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Amplifiers (AREA)
- Microwave Amplifiers (AREA)
- Junction Field-Effect Transistors (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US657395P | 1995-11-13 | 1995-11-13 | |
US657195P | 1995-11-13 | 1995-11-13 | |
PCT/US1996/018126 WO1997017964A1 (en) | 1995-11-13 | 1996-11-12 | Hemoregulatory compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO982151D0 NO982151D0 (no) | 1998-05-12 |
NO982151L NO982151L (no) | 1998-07-03 |
NO310656B1 true NO310656B1 (no) | 2001-08-06 |
Family
ID=26675804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19982151A NO310656B1 (no) | 1995-11-13 | 1998-05-12 | Hemoregulatoriske forbindelser |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0861077B1 (cs) |
JP (1) | JP2000500751A (cs) |
KR (1) | KR19990067506A (cs) |
CN (1) | CN1209061A (cs) |
AT (1) | ATE212839T1 (cs) |
AU (1) | AU711239B2 (cs) |
BR (1) | BR9611520A (cs) |
CZ (1) | CZ147098A3 (cs) |
DE (1) | DE69619123D1 (cs) |
IL (1) | IL124354A0 (cs) |
NO (1) | NO310656B1 (cs) |
NZ (1) | NZ323207A (cs) |
PL (1) | PL326631A1 (cs) |
TR (1) | TR199800850T2 (cs) |
WO (1) | WO1997017964A1 (cs) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0861080A4 (en) * | 1995-11-13 | 1999-01-20 | Smithkline Beecham Corp | HEMOREGULATORY COMPOUNDS |
DK1008380T3 (da) * | 1998-12-07 | 2004-07-12 | Dsm Ip Assets Bv | Fremgangsmåde og indretning til blanding eller dispergering af væsker |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3917626A (en) * | 1971-03-29 | 1975-11-04 | Ici Ltd | 3,6-Dioxa-1,8-octandiamido bis (pyridinium) compounds |
ZA838780B (en) * | 1982-11-26 | 1985-01-30 | Nyegaard & Co As | Peptide compounds |
US4544661A (en) * | 1983-09-23 | 1985-10-01 | Chevron Research Company | Fungicidal N-pyridyloxy alkyl amines |
JPH0381222A (ja) * | 1989-08-22 | 1991-04-05 | Yoshitomi Pharmaceut Ind Ltd | 制癌剤 |
JP2994182B2 (ja) * | 1992-07-23 | 1999-12-27 | 石原産業株式会社 | アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤 |
AU7044994A (en) * | 1993-05-24 | 1994-12-20 | Nycomed Pharma | Hemoregulatory peptides |
-
1996
- 1996-11-12 CZ CZ981470A patent/CZ147098A3/cs unknown
- 1996-11-12 JP JP9519005A patent/JP2000500751A/ja active Pending
- 1996-11-12 DE DE69619123T patent/DE69619123D1/de not_active Expired - Lifetime
- 1996-11-12 AT AT96940390T patent/ATE212839T1/de not_active IP Right Cessation
- 1996-11-12 BR BR9611520-3A patent/BR9611520A/pt active Search and Examination
- 1996-11-12 NZ NZ323207A patent/NZ323207A/xx unknown
- 1996-11-12 IL IL12435496A patent/IL124354A0/xx unknown
- 1996-11-12 WO PCT/US1996/018126 patent/WO1997017964A1/en not_active Application Discontinuation
- 1996-11-12 KR KR1019980703528A patent/KR19990067506A/ko not_active Withdrawn
- 1996-11-12 EP EP96940390A patent/EP0861077B1/en not_active Expired - Lifetime
- 1996-11-12 AU AU77282/96A patent/AU711239B2/en not_active Ceased
- 1996-11-12 CN CN96199489A patent/CN1209061A/zh active Pending
- 1996-11-12 TR TR1998/00850T patent/TR199800850T2/xx unknown
- 1996-11-12 PL PL96326631A patent/PL326631A1/xx unknown
-
1998
- 1998-05-12 NO NO19982151A patent/NO310656B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR19990067506A (ko) | 1999-08-25 |
AU7728296A (en) | 1997-06-05 |
EP0861077B1 (en) | 2002-02-06 |
EP0861077A4 (en) | 1999-03-03 |
DE69619123D1 (de) | 2002-03-21 |
AU711239B2 (en) | 1999-10-07 |
TR199800850T2 (xx) | 1998-09-21 |
IL124354A0 (en) | 1998-12-06 |
WO1997017964A1 (en) | 1997-05-22 |
NO982151D0 (no) | 1998-05-12 |
JP2000500751A (ja) | 2000-01-25 |
EP0861077A1 (en) | 1998-09-02 |
NO982151L (no) | 1998-07-03 |
PL326631A1 (en) | 1998-10-12 |
ATE212839T1 (de) | 2002-02-15 |
CZ147098A3 (cs) | 1999-02-17 |
BR9611520A (pt) | 1999-12-28 |
CN1209061A (zh) | 1999-02-24 |
NZ323207A (en) | 1999-11-29 |
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN MAY 2003 |