NO308313B1 - Nanopartikler og fremgangsmÕte for fremstilling derav - Google Patents

Nanopartikler og fremgangsmÕte for fremstilling derav

Info

Publication number
NO308313B1
NO308313B1 NO934359A NO934359A NO308313B1 NO 308313 B1 NO308313 B1 NO 308313B1 NO 934359 A NO934359 A NO 934359A NO 934359 A NO934359 A NO 934359A NO 308313 B1 NO308313 B1 NO 308313B1
Authority
NO
Norway
Prior art keywords
nanoparticles
microfluidisation
solubilising
polylactic
precipitation
Prior art date
Application number
NO934359A
Other languages
English (en)
Other versions
NO934359D0 (no
NO934359L (no
Inventor
Gilles Spenlehauer
Didier Bazile
Michel Veillard
Homme Christian Prud
Jean-Paul Michalon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO934359D0 publication Critical patent/NO934359D0/no
Publication of NO934359L publication Critical patent/NO934359L/no
Publication of NO308313B1 publication Critical patent/NO308313B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Electroluminescent Light Sources (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
  • Rear-View Mirror Devices That Are Mounted On The Exterior Of The Vehicle (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Glass Compositions (AREA)
NO934359A 1991-06-28 1993-12-01 Nanopartikler og fremgangsmÕte for fremstilling derav NO308313B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108042A FR2678178A1 (fr) 1991-06-28 1991-06-28 Procede de preparation de nanoparticules.
PCT/FR1992/000582 WO1993000388A1 (fr) 1991-06-28 1992-06-25 Procede de preparation de nanoparticules

Publications (3)

Publication Number Publication Date
NO934359D0 NO934359D0 (no) 1993-12-01
NO934359L NO934359L (no) 1993-12-01
NO308313B1 true NO308313B1 (no) 2000-08-28

Family

ID=9414445

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934359A NO308313B1 (no) 1991-06-28 1993-12-01 Nanopartikler og fremgangsmÕte for fremstilling derav

Country Status (14)

Country Link
EP (2) EP0520889A1 (no)
JP (1) JP3228742B2 (no)
AT (1) ATE135385T1 (no)
CA (1) CA2102185C (no)
DE (1) DE69209074T2 (no)
DK (1) DK0591331T3 (no)
ES (1) ES2084363T3 (no)
FI (1) FI106723B (no)
FR (1) FR2678178A1 (no)
GR (1) GR3019308T3 (no)
IE (1) IE72509B1 (no)
MX (1) MX9203354A (no)
NO (1) NO308313B1 (no)
WO (1) WO1993000388A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
FR2721510B1 (fr) * 1994-06-22 1996-07-26 Rhone Poulenc Rorer Sa Nanoparticules filtrables dans des conditions stériles.
US6007845A (en) * 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
JPH11322948A (ja) * 1998-05-08 1999-11-26 Nof Corp 高分子微粒子およびその製造方法
DE19839212C2 (de) 1998-08-28 2002-05-23 Celanese Ventures Gmbh Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen
CA2309575A1 (en) 2000-05-26 2001-11-26 James E. Guillet Internally cross-linked macromolecules
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
JP5398112B2 (ja) * 2005-10-27 2014-01-29 東レ株式会社 生分解性粒子およびその製造方法
FR2936722B1 (fr) * 2008-10-07 2013-11-22 Nanolege Inc Materiaux nanocomposites et procede de fabrication par nanoprecipitation.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8416234D0 (en) * 1984-06-26 1984-08-01 Ici Plc Biodegradable amphipathic copolymers
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules

Also Published As

Publication number Publication date
EP0591331B1 (fr) 1996-03-13
NO934359D0 (no) 1993-12-01
ES2084363T3 (es) 1996-05-01
WO1993000388A1 (fr) 1993-01-07
EP0591331A1 (fr) 1994-04-13
NO934359L (no) 1993-12-01
FR2678178B1 (no) 1995-01-13
DE69209074T2 (de) 1996-09-05
IE72509B1 (en) 1997-04-23
FR2678178A1 (fr) 1992-12-31
CA2102185C (fr) 2003-07-22
FI106723B (fi) 2001-03-30
FI935869A0 (fi) 1993-12-27
CA2102185A1 (fr) 1992-12-29
DE69209074D1 (de) 1996-04-18
MX9203354A (es) 1992-12-01
FI935869A (fi) 1993-12-27
DK0591331T3 (da) 1996-04-01
JP3228742B2 (ja) 2001-11-12
JPH06508867A (ja) 1994-10-06
EP0520889A1 (fr) 1992-12-30
IE922109A1 (en) 1992-12-30
ATE135385T1 (de) 1996-03-15
GR3019308T3 (en) 1996-06-30

Similar Documents

Publication Publication Date Title
DK0520888T3 (da) Nanopartikler på basis af en blokcopolymer af polyethylenoxid og polymælkesyre
NO308313B1 (no) Nanopartikler og fremgangsmÕte for fremstilling derav
BR9105443A (pt) Pigmentos,sistema plastico,processo de preparacao de pigmentos e uso
TR28980A (tr) Hidrofilik polimer bilesimi ve bunu ihtiva eden ürün.
BR8700670A (pt) Composicoes de polimeros controlaveis e rapidamente degradaveis,filme,e processo agricola
AT361385B (de) Verschliesseinrichtung mit festem widerlager und mit schwenkriegel, fuer die tueren von containern
DE69217338D1 (de) Carboxyvinylpolymer mit newtonischer Viskosität
IT1243097B (it) Agenti addensanti,loro preparazione ed uso, a base di derivati di polimeri o copolimeri reticolati dell'acido acrilico
DE69429387T2 (de) Polyolefin Polymerzusammensetzung und daraus gefertigter Gegenstand
FR2651717B1 (fr) Procede et dispositif de fabrication d'enveloppes en plastique verre-resine.
Sassen et al. Electron Microscopy of Austenitic Fe--Ni--Cr Alloys Containing Nitrogen
DE59100275D1 (de) Verfahren und vorrichtung zum rundumsterilisieren von gestapelten verpackungselementen, insbesondere aus kunststoff bestehende becher mit unterschiedlichen wandstaerken.
Goldfarb et al. Structure--Property Relationships of Bismaleimides Containing Oxyalkyl Linkages
Tant Crystallization kinetics and morphology development in poly(1, 4-cyclohexamethylene terephthalate) via real-time small angle light scattering.
FR2665787B1 (fr) Panneau declencheur d'alarme en cas de decoupage de toiles de peintre, laceration de banquettes et perforation de portes, murs, toits....
GR900100867A (el) Στα?ερά υδατικά εναιωρήματα ανοργάνων υλών σε βάση διοξειδίου πυριτίου και αδιάλυτα στο νερό.
Bahn Glass/Glass-Ceramic/Plastic Alloy Articles
DE3885020D1 (de) Verfahren zur Modifizierung und Adressierung organischer Filme im molekularen Bereich.
BR8900470A (pt) Pigmento inorganico,processo para tratamento de um pigmento inorganico,polimero e polietileno,polipropileno ou poliestireno
BR7001100U (pt) Dispositivo de protecao dotado de filme plastico ou tecido para irradiacao ultra violeta
DE3785764T3 (de) Niedrig viskose, halbkristalline chlorierte polyäthylenharze und gegenstände daraus.
IT8908108V0 (it) Dispositivo per l'ancoraggio sul montante, delle cinture di sicurezza,applicabile su autovetture gia' in circolazione ed una costruzione regolabile su quattro diverse posizioni con inserimento mediante spinotto e bloccaggio con sicura, utilizzabile anche da persone piu' basse di m. 1,50 e piu' alte di m. 1,90

Legal Events

Date Code Title Description
MK1K Patent expired