NO306615B1 - Kinoksaliner, deres anvendelse samt medikamenter inneholdende kinoksalinene - Google Patents

Kinoksaliner, deres anvendelse samt medikamenter inneholdende kinoksalinene

Info

Publication number
NO306615B1
NO306615B1 NO954139A NO954139A NO306615B1 NO 306615 B1 NO306615 B1 NO 306615B1 NO 954139 A NO954139 A NO 954139A NO 954139 A NO954139 A NO 954139A NO 306615 B1 NO306615 B1 NO 306615B1
Authority
NO
Norway
Prior art keywords
kinoxalins
kinoxalines
well
medications containing
alkoxy
Prior art date
Application number
NO954139A
Other languages
English (en)
Norwegian (no)
Other versions
NO954139L (no
NO954139D0 (no
Inventor
Manfred Roesner
Uta-Maria Billhardt-Troughton
Reinhard Kirsch
Joerg-Peter Kleim
Christoph Meichsner
Guenther Riess
Irvin Winkler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO954139D0 publication Critical patent/NO954139D0/no
Publication of NO954139L publication Critical patent/NO954139L/no
Publication of NO306615B1 publication Critical patent/NO306615B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Dental Preparations (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO954139A 1994-10-19 1995-10-18 Kinoksaliner, deres anvendelse samt medikamenter inneholdende kinoksalinene NO306615B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437406A DE4437406A1 (de) 1994-10-19 1994-10-19 Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (3)

Publication Number Publication Date
NO954139D0 NO954139D0 (no) 1995-10-18
NO954139L NO954139L (no) 1996-04-22
NO306615B1 true NO306615B1 (no) 1999-11-29

Family

ID=6531202

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954139A NO306615B1 (no) 1994-10-19 1995-10-18 Kinoksaliner, deres anvendelse samt medikamenter inneholdende kinoksalinene

Country Status (28)

Country Link
US (1) US5723461A (fr)
EP (1) EP0708093B1 (fr)
JP (1) JPH08225544A (fr)
KR (1) KR960014108A (fr)
CN (1) CN1094930C (fr)
AT (1) ATE198747T1 (fr)
AU (1) AU708293B2 (fr)
BR (1) BR9504456A (fr)
CA (1) CA2160859A1 (fr)
CZ (1) CZ271295A3 (fr)
DE (2) DE4437406A1 (fr)
DK (1) DK0708093T3 (fr)
ES (1) ES2154311T3 (fr)
FI (1) FI954946A (fr)
GR (1) GR3035673T3 (fr)
HK (1) HK1011988A1 (fr)
HR (1) HRP950524B1 (fr)
HU (1) HUT73485A (fr)
IL (1) IL115641A0 (fr)
MY (1) MY132057A (fr)
NO (1) NO306615B1 (fr)
NZ (1) NZ280258A (fr)
PL (1) PL184860B1 (fr)
PT (1) PT708093E (fr)
SI (1) SI9500329A (fr)
SK (1) SK128495A3 (fr)
TW (1) TW328954B (fr)
ZA (1) ZA958783B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369057B1 (en) * 1991-04-15 2002-04-09 Aventis Pharma Deutschland Gmbh Quinoxalines, processes for their preparation and their use
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
WO1999025327A2 (fr) * 1997-11-14 1999-05-27 Warner-Lambert Company Intervention de petites molecules dans la replication du vih-1
GB9901795D0 (en) * 1999-01-28 1999-03-17 Glaxo Group Ltd Chemical compounds
GB9911887D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Methods and medicaments for post exposure prophylaxis of an hiv infection
US20030114385A1 (en) * 2001-04-27 2003-06-19 Cathers Brian E. Viral enzyme activated prototoxophores and use of same to treat viral infections
WO2005018531A2 (fr) * 2003-08-26 2005-03-03 'chemical Diversity Research Institute', Ltd. Compositions pharmaceutiques, composes azo-heterocycliques et procedes de fabrication et d'utilisation correspondants
US7351709B2 (en) * 2004-06-09 2008-04-01 Wyeth Estrogen receptor ligands
WO2013163190A1 (fr) 2012-04-24 2013-10-31 Vertex Pharmaceutical Incorporated Inhibiteurs d'adn pk
LT2970218T (lt) 2013-03-12 2019-03-12 Vertex Pharmaceuticals Incorporated Dna-pk inhibitoriai
SG11201602962PA (en) 2013-10-17 2016-05-30 Vertex Pharma Co-crystals of (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)quinoline-4-carboxamide and deuterated derivatives thereof as dna-pk inhibitors
KR20190062485A (ko) 2016-09-27 2019-06-05 버텍스 파마슈티칼스 인코포레이티드 Dna-손상제 및 dna-pk 저해제의 조합을 사용한 암 치료 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59209965D1 (de) * 1991-04-15 2002-10-17 Aventis Pharma Gmbh Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung
DE4342024A1 (de) * 1993-12-09 1995-06-14 Hoechst Ag Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

Also Published As

Publication number Publication date
SK128495A3 (en) 1996-06-05
HRP950524B1 (en) 2002-06-30
JPH08225544A (ja) 1996-09-03
DE59508969D1 (de) 2001-02-22
KR960014108A (ko) 1996-05-22
FI954946A0 (fi) 1995-10-17
HU9503005D0 (en) 1995-12-28
US5723461A (en) 1998-03-03
CN1094930C (zh) 2002-11-27
ATE198747T1 (de) 2001-02-15
DK0708093T3 (da) 2001-04-30
MY132057A (en) 2007-09-28
AU708293B2 (en) 1999-07-29
EP0708093B1 (fr) 2001-01-17
AU3431695A (en) 1996-05-02
PL184860B1 (pl) 2003-01-31
NO954139L (no) 1996-04-22
EP0708093A1 (fr) 1996-04-24
NZ280258A (en) 1997-09-22
CZ271295A3 (en) 1996-08-14
GR3035673T3 (en) 2001-06-29
ES2154311T3 (es) 2001-04-01
HK1011988A1 (en) 1999-07-23
TW328954B (en) 1998-04-01
ZA958783B (en) 1996-05-09
FI954946A (fi) 1996-04-20
IL115641A0 (en) 1996-01-19
CA2160859A1 (fr) 1996-04-20
PL311016A1 (en) 1996-04-29
HRP950524A2 (en) 1997-10-31
SI9500329A (en) 1996-04-30
PT708093E (pt) 2001-06-29
NO954139D0 (no) 1995-10-18
DE4437406A1 (de) 1996-04-25
BR9504456A (pt) 1997-05-20
CN1135483A (zh) 1996-11-13
HUT73485A (en) 1996-08-28

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Legal Events

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