NO306537B1 - Anvendelse av en inhibitor for fremstilling av et medikament - Google Patents

Anvendelse av en inhibitor for fremstilling av et medikament

Info

Publication number
NO306537B1
NO306537B1 NO933235A NO933235A NO306537B1 NO 306537 B1 NO306537 B1 NO 306537B1 NO 933235 A NO933235 A NO 933235A NO 933235 A NO933235 A NO 933235A NO 306537 B1 NO306537 B1 NO 306537B1
Authority
NO
Norway
Prior art keywords
drug
inhibitor
preparation
thrombin
medicament
Prior art date
Application number
NO933235A
Other languages
English (en)
Norwegian (no)
Other versions
NO933235L (no
NO933235D0 (no
Inventor
Christopher Berry
Patrice Ferrari
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO933235D0 publication Critical patent/NO933235D0/no
Publication of NO933235L publication Critical patent/NO933235L/no
Publication of NO306537B1 publication Critical patent/NO306537B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO933235A 1992-09-11 1993-09-10 Anvendelse av en inhibitor for fremstilling av et medikament NO306537B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9210833A FR2695562B1 (fr) 1992-09-11 1992-09-11 Utilisation d'un inhibiteur direct de la thrombine pour la fabrication d'un médicament à activité thrombolytique.

Publications (3)

Publication Number Publication Date
NO933235D0 NO933235D0 (no) 1993-09-10
NO933235L NO933235L (no) 1994-03-14
NO306537B1 true NO306537B1 (no) 1999-11-22

Family

ID=9433400

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933235A NO306537B1 (no) 1992-09-11 1993-09-10 Anvendelse av en inhibitor for fremstilling av et medikament

Country Status (18)

Country Link
US (1) US5583113A (ko)
EP (1) EP0589741B1 (ko)
JP (1) JPH06228007A (ko)
KR (1) KR100261526B1 (ko)
CN (1) CN1066961C (ko)
AT (1) ATE163856T1 (ko)
AU (1) AU4628193A (ko)
CA (1) CA2105888C (ko)
CZ (1) CZ188893A3 (ko)
DE (1) DE69317343T2 (ko)
DK (1) DK0589741T3 (ko)
ES (1) ES2115741T4 (ko)
FR (1) FR2695562B1 (ko)
IL (1) IL106981A (ko)
NO (1) NO306537B1 (ko)
SK (1) SK96993A3 (ko)
TW (1) TW284691B (ko)
ZA (1) ZA936707B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830448A (en) * 1994-06-16 1998-11-03 Genentech, Inc. Compositions and methods for the treatment of tumors
DE4421052A1 (de) 1994-06-17 1995-12-21 Basf Ag Neue Thrombininhibitoren, ihre Herstellung und Verwendung
EA199700186A1 (ru) * 1995-02-17 1998-02-26 Басф Акциенгезельшафт Новые дипептидные амидины, используемые в качестве ингибиторов тромбина
US5840733A (en) * 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
JP2002501081A (ja) 1998-01-26 2002-01-15 ビーエーエスエフ アクチェンゲゼルシャフト トロンビンインヒビター
CN101598725B (zh) * 2009-06-23 2012-07-18 南通大学附属医院 阿加曲班在血细胞和生化常规分析中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258192A (en) * 1977-12-16 1981-03-24 Mitsubishi Chemical Industries Limited N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
US4318904A (en) * 1980-04-25 1982-03-09 Research Corporation Peptide affinity labels for thrombin and other trypsin-like proteases
US4929602A (en) * 1987-11-25 1990-05-29 Scripps Clinic And Research Foundation Method of inhibiting platelet dependent arterial thrombosis
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin

Also Published As

Publication number Publication date
CN1066961C (zh) 2001-06-13
TW284691B (ko) 1996-09-01
AU4628193A (en) 1994-03-17
IL106981A (en) 1999-03-12
CZ188893A3 (en) 1994-03-16
KR940006600A (ko) 1994-04-25
CA2105888A1 (fr) 1994-03-12
DE69317343D1 (de) 1998-04-16
EP0589741A1 (fr) 1994-03-30
NO933235L (no) 1994-03-14
ZA936707B (en) 1994-03-30
US5583113A (en) 1996-12-10
DE69317343T2 (de) 1998-10-08
CN1087015A (zh) 1994-05-25
NO933235D0 (no) 1993-09-10
KR100261526B1 (ko) 2000-07-15
ES2115741T3 (es) 1998-07-01
JPH06228007A (ja) 1994-08-16
ATE163856T1 (de) 1998-03-15
SK96993A3 (en) 1994-08-10
FR2695562A1 (fr) 1994-03-18
CA2105888C (fr) 2008-04-15
IL106981A0 (en) 1993-12-28
ES2115741T4 (es) 2012-07-04
EP0589741B1 (fr) 1998-03-11
DK0589741T3 (da) 1998-12-21
FR2695562B1 (fr) 1994-10-14

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees