NO304647B1 - (S)-alfa-fenyl-2-pyridinetanamin (S)-malat, farmas÷ytisk preparat inneholde denne forbindelsen og dens anvendelse til fremstilling av legemiddel - Google Patents

(S)-alfa-fenyl-2-pyridinetanamin (S)-malat, farmas÷ytisk preparat inneholde denne forbindelsen og dens anvendelse til fremstilling av legemiddel

Info

Publication number
NO304647B1
NO304647B1 NO951546A NO953846A NO304647B1 NO 304647 B1 NO304647 B1 NO 304647B1 NO 951546 A NO951546 A NO 951546A NO 953846 A NO953846 A NO 953846A NO 304647 B1 NO304647 B1 NO 304647B1
Authority
NO
Norway
Prior art keywords
malate
alpha
phenyl
pyridinethanamine
drug
Prior art date
Application number
NO951546A
Other languages
English (en)
Norwegian (no)
Other versions
NO953846D0 (no
NO953846L (no
Inventor
Robert John Murray
Donald Mathisen
Michael Balestra
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB1993/000689 external-priority patent/WO1993020052A1/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO953846D0 publication Critical patent/NO953846D0/no
Publication of NO953846L publication Critical patent/NO953846L/no
Publication of NO304647B1 publication Critical patent/NO304647B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO951546A 1993-04-01 1995-09-28 (S)-alfa-fenyl-2-pyridinetanamin (S)-malat, farmas÷ytisk preparat inneholde denne forbindelsen og dens anvendelse til fremstilling av legemiddel NO304647B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/GB1993/000689 WO1993020052A1 (en) 1992-04-03 1993-04-01 Enantiomeric 1-phenyl-2-(2-pyridinyl)ethylamine for the treatment of neurodegenerative disorders
GB939320273A GB9320273D0 (en) 1993-04-01 1993-10-01 Compound useful in therapy
PCT/GB1994/000651 WO1994022831A1 (en) 1993-04-01 1994-03-29 (s)-alpha-phenyl-2-pyridineethanamine (s)-malate and its use as a medicament

Publications (3)

Publication Number Publication Date
NO953846D0 NO953846D0 (no) 1995-09-28
NO953846L NO953846L (no) 1995-11-21
NO304647B1 true NO304647B1 (no) 1999-01-25

Family

ID=26302299

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951546A NO304647B1 (no) 1993-04-01 1995-09-28 (S)-alfa-fenyl-2-pyridinetanamin (S)-malat, farmas÷ytisk preparat inneholde denne forbindelsen og dens anvendelse til fremstilling av legemiddel

Country Status (19)

Country Link
EP (1) EP0691957B1 (de)
JP (1) JP3023987B2 (de)
CN (1) CN1047168C (de)
AT (1) ATE156813T1 (de)
AU (1) AU682348B2 (de)
CA (1) CA2159478C (de)
DE (1) DE69404974T2 (de)
DK (1) DK0691957T3 (de)
DZ (1) DZ1765A1 (de)
ES (1) ES2105672T3 (de)
FI (1) FI109018B (de)
GB (1) GB9320273D0 (de)
GR (1) GR3025081T3 (de)
IL (1) IL109108A (de)
MA (1) MA23154A1 (de)
NO (1) NO304647B1 (de)
PH (1) PH30950A (de)
SG (1) SG48204A1 (de)
WO (1) WO1994022831A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG52662A1 (en) * 1988-08-12 1998-09-28 Astra Ab Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties
ZA942140B (en) * 1993-04-01 1994-10-03 Fisons Corp Salt of (S)-alpha-phenyl-2-pyridineethanamine useful in therapy
SE9901338D0 (sv) * 1999-04-15 1999-04-15 Astra Pharma Prod Novel process
SE9901340D0 (sv) * 1999-04-15 1999-04-15 Astra Pharma Prod Novel process
DE10301650A1 (de) * 2003-01-17 2004-07-29 Johannes-Gutenberg-Universität Mainz Medizinisch nützliche 1-Phenyl-2-aminomethylnaphthaline, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung
NZ593282A (en) 2008-12-24 2013-06-28 Astrazeneca Ab Ethanamine compounds and their use for treating depression

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422191A (en) * 1965-01-21 1969-01-14 Synergistics Inc Compositions and methods for tranquilization employing salts of n-morpholine ethanol
WO1993020052A1 (en) * 1992-04-03 1993-10-14 Fisons Corporation Enantiomeric 1-phenyl-2-(2-pyridinyl)ethylamine for the treatment of neurodegenerative disorders
SG52662A1 (en) * 1988-08-12 1998-09-28 Astra Ab Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties
JP2514855B2 (ja) * 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 光学活性なアラニンアニリド誘導体の酸付加塩

Also Published As

Publication number Publication date
GR3025081T3 (en) 1998-01-30
DK0691957T3 (da) 1997-10-27
MA23154A1 (fr) 1994-12-31
GB9320273D0 (en) 1993-11-17
DZ1765A1 (fr) 2002-02-17
NO953846D0 (no) 1995-09-28
EP0691957A1 (de) 1996-01-17
EP0691957B1 (de) 1997-08-13
PH30950A (en) 1997-12-23
CA2159478A1 (en) 1994-10-13
JP3023987B2 (ja) 2000-03-21
WO1994022831A1 (en) 1994-10-13
CN1047168C (zh) 1999-12-08
CN1098095A (zh) 1995-02-01
NO953846L (no) 1995-11-21
FI109018B (fi) 2002-05-15
AU682348B2 (en) 1997-10-02
FI954645A0 (fi) 1995-09-29
ES2105672T3 (es) 1997-10-16
FI954645A (fi) 1995-11-29
AU6380294A (en) 1994-10-24
IL109108A (en) 1999-01-26
JPH08508292A (ja) 1996-09-03
IL109108A0 (en) 1994-06-24
ATE156813T1 (de) 1997-08-15
DE69404974D1 (de) 1997-09-18
DE69404974T2 (de) 1997-12-18
CA2159478C (en) 2005-01-25
SG48204A1 (en) 1998-04-17

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