NO302575B1 - Kompleksforbindelser, farmasöytiske preparater inneholdende disse og deres anvendelse ved diagnostikk og stråleterapi - Google Patents

Kompleksforbindelser, farmasöytiske preparater inneholdende disse og deres anvendelse ved diagnostikk og stråleterapi

Info

Publication number
NO302575B1
NO302575B1 NO952925A NO952925A NO302575B1 NO 302575 B1 NO302575 B1 NO 302575B1 NO 952925 A NO952925 A NO 952925A NO 952925 A NO952925 A NO 952925A NO 302575 B1 NO302575 B1 NO 302575B1
Authority
NO
Norway
Prior art keywords
pct
radiation therapy
diagnostics
pharmaceutical preparations
complex compounds
Prior art date
Application number
NO952925A
Other languages
English (en)
Norwegian (no)
Other versions
NO952925D0 (no
NO952925L (no
Inventor
Heribert Schmitt-Willich
Johannes Platzek
Heinz Gries
Bernd Raduechel
Orlin Petrov
Andreas Muehler
Thomas Frenzel
Hubert Vogler
Hans Bauer
Klaus Nickisch
Jean-Claude Hilscher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO952925D0 publication Critical patent/NO952925D0/no
Publication of NO952925L publication Critical patent/NO952925L/no
Publication of NO302575B1 publication Critical patent/NO302575B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO952925A 1993-01-25 1995-07-24 Kompleksforbindelser, farmasöytiske preparater inneholdende disse og deres anvendelse ved diagnostikk og stråleterapi NO302575B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4302287A DE4302287A1 (de) 1993-01-25 1993-01-25 Derivatisierte DTPA-Komplexe, diese Verbindungen enthaltende pharmazeutische Mittel, ihre Verwendung und Verfahren zu deren Herstellung
PCT/EP1994/000033 WO1994017029A1 (de) 1993-01-25 1994-01-08 Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung als nmr- und röntgenkontrastmittel und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO952925D0 NO952925D0 (no) 1995-07-24
NO952925L NO952925L (no) 1995-07-24
NO302575B1 true NO302575B1 (no) 1998-03-23

Family

ID=6479074

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952925A NO302575B1 (no) 1993-01-25 1995-07-24 Kompleksforbindelser, farmasöytiske preparater inneholdende disse og deres anvendelse ved diagnostikk og stråleterapi

Country Status (18)

Country Link
US (1) US5733522A (zh)
EP (1) EP0680464B1 (zh)
JP (1) JPH08506102A (zh)
KR (1) KR960700219A (zh)
AT (1) ATE151406T1 (zh)
AU (1) AU681620B2 (zh)
CA (1) CA2154559A1 (zh)
DE (2) DE4302287A1 (zh)
DK (1) DK0680464T3 (zh)
ES (1) ES2103121T3 (zh)
GR (1) GR3023954T3 (zh)
HU (1) HUT72628A (zh)
IL (1) IL108433A (zh)
NO (1) NO302575B1 (zh)
NZ (1) NZ259708A (zh)
TW (1) TW314520B (zh)
WO (1) WO1994017029A1 (zh)
ZA (1) ZA94512B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19507820A1 (de) * 1995-02-21 1996-08-22 Schering Ag Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
US6458337B1 (en) 1996-08-02 2002-10-01 Dibra S.P.A Diagnostic imaging contrast agent with improved in serum relaxivity
IT1290417B1 (it) * 1996-08-02 1998-12-03 Bracco Spa Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed
US6403055B1 (en) 1996-08-02 2002-06-11 Dibra S.P.A. Diagnostic imaging contrast agent with improved in serum relaxivity
DE19641197C2 (de) * 1996-09-24 1999-02-18 Schering Ag Ionenpaare und ihre Verwendung als Kontrastmittel
DE19646762B4 (de) * 1996-11-04 2004-05-13 Schering Ag Verwendung von Metallverbindungen zur Herstellung von Mitteln zur Strahlentherapie von Tumoren
CA2478924A1 (en) * 2002-03-14 2003-09-18 Qlt Inc. Cancer associated araf1 protein kinase and its uses
US20070048803A1 (en) * 2005-08-25 2007-03-01 Lee Peter P Immune profiling of lymph nodes associated with cancer
US11420910B2 (en) 2014-10-30 2022-08-23 Katholieke Universitet Leuven Methods for low temperature fluorine-18 radiolabeling of biomolecules

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA713093A (en) * 1965-07-06 Dexter Martin Complex forming polyaminopoly-carboxylic acids
DE1155122B (de) * 1960-10-17 1963-10-03 Geigy Ag J R Verfahren zur Herstellung von neuen alicyclischen Polyaminopolyessigsaeuren bzw. deren komplexen Metallverbindungen
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
US4880008A (en) * 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5039512A (en) * 1986-08-04 1991-08-13 Salutar, Inc. NMR imaging with paramagnetic polyvalent metal salts of poly-(acid-alkylene-amino)-alkanes
AU608759B2 (en) * 1986-08-04 1991-04-18 Amersham Health Salutar Inc NMR imaging with paramagnetic polyvalents metal salts of poly-(acid-alkylene-amido)-alkanes
US5482700A (en) * 1987-03-31 1996-01-09 Schering Aktiengesellschaft Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast
WO1989000557A1 (en) * 1987-07-16 1989-01-26 Cockbain, Julian, Roderick, Michaelson Aminopolycarboxylic acids and derivatives thereof
US5399340A (en) * 1987-09-24 1995-03-21 Schering Aktiengesellschaft Use of amide complex compounds
US5089663A (en) * 1989-06-29 1992-02-18 Associated Universities, Inc. Cyclohexyl-triethylenetetraamine hexacetic acid
US5021571A (en) * 1989-06-29 1991-06-04 Associated Universities, Inc. Cyclohexyl EDTA monoanhydride
DE3922005A1 (de) * 1989-06-30 1991-01-10 Schering Ag Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung
US5124471A (en) * 1990-03-26 1992-06-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Bifunctional dtpa-type ligand
JPH08510458A (ja) * 1993-06-02 1996-11-05 ブラッコ エッセ．ピ．ア． 沃素化された常磁性キレートおよびそれらの造影剤としての使用法
WO1995015319A1 (en) * 1993-12-03 1995-06-08 Bracco S.P.A. Paramagnetic chelates for nuclear magnetic resonance diagnosis

Also Published As

Publication number Publication date
DK0680464T3 (da) 1997-10-20
EP0680464B1 (de) 1997-04-09
DE4302287A1 (de) 1994-07-28
TW314520B (zh) 1997-09-01
NO952925D0 (no) 1995-07-24
NO952925L (no) 1995-07-24
ES2103121T3 (es) 1997-08-16
HUT72628A (en) 1996-05-28
ZA94512B (en) 1994-09-05
IL108433A0 (en) 1994-04-12
WO1994017029A1 (de) 1994-08-04
IL108433A (en) 1999-03-12
EP0680464A1 (de) 1995-11-08
HU9501878D0 (en) 1995-08-28
KR960700219A (ko) 1996-01-19
JPH08506102A (ja) 1996-07-02
AU5860494A (en) 1994-08-15
CA2154559A1 (en) 1994-07-26
NZ259708A (en) 1997-01-29
DE59402379D1 (de) 1997-05-15
US5733522A (en) 1998-03-31
GR3023954T3 (en) 1997-09-30
ATE151406T1 (de) 1997-04-15
AU681620B2 (en) 1997-09-04

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