NO20092202L - Amorf form av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl}-N-metylacetamid - Google Patents

Amorf form av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl}-N-metylacetamid

Info

Publication number
NO20092202L
NO20092202L NO20092202A NO20092202A NO20092202L NO 20092202 L NO20092202 L NO 20092202L NO 20092202 A NO20092202 A NO 20092202A NO 20092202 A NO20092202 A NO 20092202A NO 20092202 L NO20092202 L NO 20092202L
Authority
NO
Norway
Prior art keywords
methylacetamide
pyrazolo
pyrimidin
thiophene
fluoro
Prior art date
Application number
NO20092202A
Other languages
English (en)
Other versions
NO341702B1 (no
Inventor
Luis Anglada
Albert Palomer
Antonio Guglietta
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO20092202L publication Critical patent/NO20092202L/no
Publication of NO341702B1 publication Critical patent/NO341702B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20092202A 2006-11-08 2009-06-08 Amorf form av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl}-N-metylacetamid NO341702B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86481406P 2006-11-08 2006-11-08
EP06123652A EP1921079A1 (en) 2006-11-08 2006-11-08 Amorphous form of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
PCT/EP2007/062014 WO2008055934A1 (en) 2006-11-08 2007-11-07 Amorphous form of n-{2-fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo [1,5-a]pyrimidin-7-yl]-phenyl-n-methyl-acetamide

Publications (2)

Publication Number Publication Date
NO20092202L true NO20092202L (no) 2009-06-08
NO341702B1 NO341702B1 (no) 2018-01-02

Family

ID=37836942

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092202A NO341702B1 (no) 2006-11-08 2009-06-08 Amorf form av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl}-N-metylacetamid

Country Status (22)

Country Link
US (1) US8338436B2 (no)
EP (2) EP1921079A1 (no)
JP (1) JP5274472B2 (no)
KR (1) KR101474033B1 (no)
CN (1) CN101563350B (no)
AR (1) AR063579A1 (no)
AU (1) AU2007316607B2 (no)
BR (1) BRPI0718538A2 (no)
CA (1) CA2667936C (no)
CL (1) CL2007003218A1 (no)
DK (1) DK2086978T3 (no)
ES (1) ES2402981T3 (no)
HK (1) HK1130789A1 (no)
MX (1) MX2009004636A (no)
NO (1) NO341702B1 (no)
PL (1) PL2086978T3 (no)
PT (1) PT2086978E (no)
RU (1) RU2450005C2 (no)
SI (1) SI2086978T1 (no)
TW (1) TWI414526B (no)
UY (1) UY30651A1 (no)
WO (1) WO2008055934A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2478640C1 (ru) * 2012-02-07 2013-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" N-АРИЛ-2,3-ДИАРОИЛ-8,10-ДИМЕТИЛПИРИДО[2',3':3,4]ПИРАЗОЛО[1,5-α]ПИРИМИДИН-4-КАРБОКСАМИДЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005014597A1 (en) * 2003-07-24 2005-02-17 Ferrer Internacional, S.A. N-[3-(3-SUBSTITUTED-PYRAZOLO[1,5-a]PYRIMIDIN-7-YL)PHENYL]-SULFONAMIDES, AND COMPOSITIONS, AND METHODS RELATED THERETO
US20060063785A1 (en) * 2004-09-17 2006-03-23 Wang Yanong D Substituted pyrazolo[1,5-a] pyrimidines and process for making same
US20060189633A1 (en) * 2005-02-18 2006-08-24 Mai De Ltd. Preparation of amorphous form of indiplon
WO2006136530A1 (en) * 2005-06-21 2006-12-28 Ferrer Internacional, S.A. Halogenated pyrazolo [1,5-a]pyrimidines, processes, uses as gaba-a receptors ligand, compositions and intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
US4521422A (en) 1983-06-23 1985-06-04 American Cyanamid Company Aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
WO2006033795A2 (en) 2004-09-17 2006-03-30 Wyeth Substituted pyrazolo [1, 5-a] pyrimidines for inhibiting abnormal cell growth
EP1918290A1 (en) * 2006-10-11 2008-05-07 Ferrer Internacional, S.A. Polymorph B of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005014597A1 (en) * 2003-07-24 2005-02-17 Ferrer Internacional, S.A. N-[3-(3-SUBSTITUTED-PYRAZOLO[1,5-a]PYRIMIDIN-7-YL)PHENYL]-SULFONAMIDES, AND COMPOSITIONS, AND METHODS RELATED THERETO
US20060063785A1 (en) * 2004-09-17 2006-03-23 Wang Yanong D Substituted pyrazolo[1,5-a] pyrimidines and process for making same
US20060189633A1 (en) * 2005-02-18 2006-08-24 Mai De Ltd. Preparation of amorphous form of indiplon
WO2006136530A1 (en) * 2005-06-21 2006-12-28 Ferrer Internacional, S.A. Halogenated pyrazolo [1,5-a]pyrimidines, processes, uses as gaba-a receptors ligand, compositions and intermediates

Also Published As

Publication number Publication date
RU2450005C2 (ru) 2012-05-10
SI2086978T1 (sl) 2013-05-31
PL2086978T3 (pl) 2013-07-31
TWI414526B (zh) 2013-11-11
AU2007316607B2 (en) 2013-02-21
JP5274472B2 (ja) 2013-08-28
CN101563350A (zh) 2009-10-21
KR101474033B1 (ko) 2014-12-17
EP2086978B1 (en) 2013-01-23
HK1130789A1 (en) 2010-01-08
CL2007003218A1 (es) 2008-05-16
EP2086978A1 (en) 2009-08-12
BRPI0718538A2 (pt) 2013-11-19
JP2010509282A (ja) 2010-03-25
KR20090091154A (ko) 2009-08-26
CN101563350B (zh) 2012-11-07
UY30651A1 (es) 2008-05-02
US8338436B2 (en) 2012-12-25
NO341702B1 (no) 2018-01-02
US20100137339A1 (en) 2010-06-03
AU2007316607A1 (en) 2008-05-15
RU2009121672A (ru) 2010-12-20
CA2667936A1 (en) 2008-05-15
MX2009004636A (es) 2009-05-27
ES2402981T3 (es) 2013-05-13
AR063579A1 (es) 2009-02-04
PT2086978E (pt) 2013-04-04
TW200825086A (en) 2008-06-16
WO2008055934A1 (en) 2008-05-15
EP1921079A1 (en) 2008-05-14
DK2086978T3 (da) 2013-04-15
CA2667936C (en) 2013-10-15

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