NO20091334L - Fremgangsmate for syntese av klopidogrel og nye former for farmasoytisk akseptable salter derav - Google Patents
Fremgangsmate for syntese av klopidogrel og nye former for farmasoytisk akseptable salter deravInfo
- Publication number
- NO20091334L NO20091334L NO20091334A NO20091334A NO20091334L NO 20091334 L NO20091334 L NO 20091334L NO 20091334 A NO20091334 A NO 20091334A NO 20091334 A NO20091334 A NO 20091334A NO 20091334 L NO20091334 L NO 20091334L
- Authority
- NO
- Norway
- Prior art keywords
- clopidogrel
- synthesis
- pharmaceutically acceptable
- acceptable salts
- novel forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200600220A SI22383A (sl) | 2006-09-22 | 2006-09-22 | Nov postopek sinteze klopidogrela in nove oblike njegovih farmacevtsko sprejemljivih soli |
PCT/EP2007/060127 WO2008034912A2 (en) | 2006-09-22 | 2007-09-24 | Process for the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20091334L true NO20091334L (no) | 2009-04-22 |
Family
ID=39092310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091334A NO20091334L (no) | 2006-09-22 | 2009-03-31 | Fremgangsmate for syntese av klopidogrel og nye former for farmasoytisk akseptable salter derav |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2078025B1 (de) |
ES (1) | ES2577294T3 (de) |
HR (1) | HRP20160809T1 (de) |
HU (1) | HUE029319T2 (de) |
NO (1) | NO20091334L (de) |
PL (1) | PL2078025T3 (de) |
SI (2) | SI22383A (de) |
WO (1) | WO2008034912A2 (de) |
ZA (1) | ZA200902575B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2107061A1 (de) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Herstellungsverfahren für optisch angereichertes Clopidogrel |
WO2011051976A2 (en) * | 2009-10-30 | 2011-05-05 | Matrix Laboratories Ltd | An improved process for the preparation of clopidogrel bisulfate form i |
WO2012007019A1 (en) * | 2010-07-13 | 2012-01-19 | Pharmathen S.A. | Process for the preparation of clopidogrel and salts thereof |
CN102120745B (zh) * | 2011-01-31 | 2013-04-10 | 天津红日药业股份有限公司 | 一种盐酸氯吡格雷的晶型ⅰ及其制备方法和用途 |
WO2016011783A1 (zh) * | 2014-12-31 | 2016-01-28 | 天津大学 | 一种制备球形硫酸氢氯吡格雷i晶型的方法 |
CN111606923B (zh) * | 2020-06-24 | 2021-08-24 | 武汉理工大学 | 一种外消旋氯吡格雷的合成方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
FR2779726B1 (fr) * | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
CN100338068C (zh) * | 2001-01-24 | 2007-09-19 | 卡地拉健康护理有限公司 | 制备氯吡格雷的方法 |
PL370802A1 (en) * | 2001-12-18 | 2005-05-30 | Teva Pharmaceutical Industries Ltd. | Polymorphs of clopidogrel hydrogensulfate |
IL166593A0 (en) * | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
GB2393181A (en) * | 2002-09-19 | 2004-03-24 | Cipla Ltd | Amorphous clopidogrel |
WO2004108665A2 (en) * | 2003-04-24 | 2004-12-16 | Sun Pharmaceutical Industries Limited | A process for preparation of clopidogrel |
US20050059696A1 (en) * | 2003-05-08 | 2005-03-17 | Dr. Reddy's Laboratories Limited | Process for the recovery of S -(+)-methyl- (2-chlorophenyl)- (6,7-dihydro- 4H-thieno [3,2-c] pyrid-5-yl) acetate hydrogen sulfate (clopidogrel bisulfate) from its (R) and mixture of (R) and (S)- isomers |
US7291735B2 (en) * | 2003-08-04 | 2007-11-06 | The Company Of Wockhard Limited | Process for the manufacture of (+)-(s)-clopidogrel bisulfate form-1 |
DE10337773A1 (de) * | 2003-08-13 | 2005-03-24 | Krka Tovarna Zdravil, D.D. | Kristallisation von festen Formen von Clopidogrel-Additionssalzen |
SI1740593T1 (sl) * | 2004-04-19 | 2016-08-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Postopek za pripravo polimorfne oblike I klopidogrel hidrogen sulfata |
CZ20041048A3 (cs) * | 2004-10-18 | 2005-11-16 | Zentiva, A. S | Způsob výroby klopidogrelu |
US7772398B2 (en) * | 2005-03-11 | 2010-08-10 | Dr. Reddy's Laboratories, Inc. | Process for making crystalline form I of clopidogrel hydrogen sulphate |
KR100678287B1 (ko) * | 2005-06-23 | 2007-02-02 | 한미약품 주식회사 | 클로피도그렐의 제조방법 및 이에 사용되는 중간체 |
KR20070094230A (ko) * | 2006-03-17 | 2007-09-20 | 한미약품 주식회사 | 클로피도그렐 캄파술폰산염 또는 이의 결정다형을 함유하는약학 조성물 |
-
2006
- 2006-09-22 SI SI200600220A patent/SI22383A/sl not_active IP Right Cessation
-
2007
- 2007-09-24 HU HUE07820533A patent/HUE029319T2/en unknown
- 2007-09-24 WO PCT/EP2007/060127 patent/WO2008034912A2/en active Application Filing
- 2007-09-24 SI SI200731802A patent/SI2078025T1/sl unknown
- 2007-09-24 PL PL07820533.3T patent/PL2078025T3/pl unknown
- 2007-09-24 EP EP07820533.3A patent/EP2078025B1/de active Active
- 2007-09-24 ES ES07820533.3T patent/ES2577294T3/es active Active
-
2009
- 2009-03-31 NO NO20091334A patent/NO20091334L/no not_active Application Discontinuation
- 2009-04-15 ZA ZA200902575A patent/ZA200902575B/xx unknown
-
2016
- 2016-07-06 HR HRP20160809TT patent/HRP20160809T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
HUE029319T2 (en) | 2017-02-28 |
EP2078025B1 (de) | 2016-04-13 |
ES2577294T3 (es) | 2016-07-14 |
ZA200902575B (en) | 2010-03-31 |
SI2078025T1 (sl) | 2016-08-31 |
EP2078025A2 (de) | 2009-07-15 |
PL2078025T3 (pl) | 2016-09-30 |
WO2008034912A3 (en) | 2008-08-07 |
WO2008034912A2 (en) | 2008-03-27 |
HRP20160809T1 (hr) | 2016-09-23 |
SI22383A (sl) | 2008-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |