NO20091293L - Fremstilling og rensing av mupirocin kalsium - Google Patents

Fremstilling og rensing av mupirocin kalsium

Info

Publication number
NO20091293L
NO20091293L NO20091293A NO20091293A NO20091293L NO 20091293 L NO20091293 L NO 20091293L NO 20091293 A NO20091293 A NO 20091293A NO 20091293 A NO20091293 A NO 20091293A NO 20091293 L NO20091293 L NO 20091293L
Authority
NO
Norway
Prior art keywords
mupirocin
purification
preparation
calcium
resin
Prior art date
Application number
NO20091293A
Other languages
English (en)
Other versions
NO342269B1 (no
Inventor
Lene Aassveen
Original Assignee
Syngen Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngen Biotech Co Ltd filed Critical Syngen Biotech Co Ltd
Publication of NO20091293L publication Critical patent/NO20091293L/no
Publication of NO342269B1 publication Critical patent/NO342269B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Den foreliggende oppfinnelse angår metoder for fremstilling og rensing av mupirocinkalsium. Prosessen omfatter å adsorbere mupirocin til en hydrofob adsorbentresin, eksponere det bundne mupirocin til en kalsiuminneholdende løsning, vaske urenheter vekk fra resinet og eluere renset mupirocin fra resinet.
NO20091293A 2006-08-30 2009-03-27 Fremstilling og rensing av mupirocin kalsium NO342269B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0617069A GB2441328A (en) 2006-08-30 2006-08-30 A method for obtaining mupirocin calcium
PCT/EP2007/007547 WO2008025534A1 (en) 2006-08-30 2007-08-29 Preparation and purification of mupirocin calcium

Publications (2)

Publication Number Publication Date
NO20091293L true NO20091293L (no) 2009-03-27
NO342269B1 NO342269B1 (no) 2018-04-30

Family

ID=37137032

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091293A NO342269B1 (no) 2006-08-30 2009-03-27 Fremstilling og rensing av mupirocin kalsium

Country Status (12)

Country Link
US (1) US7868191B2 (no)
EP (1) EP2081926B1 (no)
JP (1) JP5277167B2 (no)
CN (1) CN101511826B (no)
AT (1) ATE556073T1 (no)
AU (1) AU2007291508B2 (no)
CA (1) CA2649758C (no)
GB (1) GB2441328A (no)
NO (1) NO342269B1 (no)
PL (1) PL2081926T3 (no)
TW (1) TWI406860B (no)
WO (1) WO2008025534A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2441328A (en) 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium
CN101591333B (zh) * 2009-07-02 2012-01-04 山东健威生物工程有限公司 一种提纯假单胞菌酸a的方法
CN104370896A (zh) * 2013-11-29 2015-02-25 江苏汉邦科技有限公司 一种纯化假单孢菌素的方法
CN116018342A (zh) * 2020-08-25 2023-04-25 杭州中美华东制药有限公司 一种莫匹罗星的提取方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3977943A (en) * 1971-06-12 1976-08-31 Beecham Group Limited Antibiotics
US4071536A (en) * 1971-06-12 1978-01-31 Beecham Group Limited Antibiotics
GB1395907A (en) * 1971-06-12 1975-05-29 Beecham Group Ltd Antibiotics
CA1103264A (en) 1977-09-30 1981-06-16 Norman H. Rogers Purification of pseudomonic acid
CA1115699A (en) * 1978-05-20 1982-01-05 Alan D. Curzons Lithium pseudomonate and its preparation
GB8415579D0 (en) * 1984-06-19 1984-07-25 Beecham Group Plc Compounds
JPH01268682A (ja) * 1988-04-21 1989-10-26 Minofuaagen Seiyaku Honpo:Goushi 腎機能改善剤及びリソスペルミン酸塩の製造方法
US5235037A (en) * 1991-08-15 1993-08-10 American Cyanamid Company Vancomycin precipitation process
EP1147210A4 (en) 1999-02-03 2004-06-02 Biogal Gyogyszergyar METHOD FOR ISOLATING PSEUDOMONIC ACID A FROM A CULTURAL SOLUTION CONTAINING PSEUDOMONIC ACID COMPLEX
EP1455769A4 (en) * 2001-12-28 2004-09-22 Biogal Gyogyszergyar METHOD FOR PRODUCING CRYSTALLINE AND AMORPHIC MUPIROCIN CALCIUM
ATE458476T1 (de) * 2004-06-01 2010-03-15 Teva Gyogyszergyar Zartkoeruen Verfahren für die zubereitung der amorphen form eines medikamentes
ES2455518T3 (es) * 2005-02-21 2014-04-15 Syngen Biotech Co., Ltd. Purificación de mupirocina
GB2441328A (en) 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium

Also Published As

Publication number Publication date
PL2081926T3 (pl) 2012-12-31
AU2007291508A1 (en) 2008-03-06
EP2081926A1 (en) 2009-07-29
CA2649758C (en) 2014-03-18
EP2081926B1 (en) 2012-05-02
AU2007291508B2 (en) 2011-11-24
ATE556073T1 (de) 2012-05-15
JP2010501608A (ja) 2010-01-21
GB0617069D0 (en) 2006-10-11
CA2649758A1 (en) 2008-03-06
GB2441328A (en) 2008-03-05
JP5277167B2 (ja) 2013-08-28
WO2008025534A1 (en) 2008-03-06
NO342269B1 (no) 2018-04-30
US7868191B2 (en) 2011-01-11
US20090240071A1 (en) 2009-09-24
TWI406860B (zh) 2013-09-01
CN101511826B (zh) 2011-06-22
CN101511826A (zh) 2009-08-19
TW200825070A (en) 2008-06-16

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