NO20091239L - Konjugater av disorazoler og deres derivater med celle bindingsmolekyler, nye disorazol derivater, fremgangsmate for fremstilling og anvendelse derav - Google Patents
Konjugater av disorazoler og deres derivater med celle bindingsmolekyler, nye disorazol derivater, fremgangsmate for fremstilling og anvendelse deravInfo
- Publication number
- NO20091239L NO20091239L NO20091239A NO20091239A NO20091239L NO 20091239 L NO20091239 L NO 20091239L NO 20091239 A NO20091239 A NO 20091239A NO 20091239 A NO20091239 A NO 20091239A NO 20091239 L NO20091239 L NO 20091239L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- conjugates
- disorazoles
- binding molecules
- cell binding
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer konjugater av disorazoler og deres derivater med cellebindingsmolekyler, slike som peptider, proteiner, hormoner, blodprotemer og antistoffer. Foreliggende oppfinnelse tilveiebringer videre nye disorazolderivater og fremgangsmåter for fremstilling av slike konjugater og disorazolderivater. Disse forbindelsene kan anvendes som medikamenter for behandling av fysiologiske og/eller patofysiologiske tilstander hos pattedyr, særlig for behandling av forskjellige tumorer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84235706P | 2006-09-06 | 2006-09-06 | |
EP06018750A EP1900742A1 (en) | 2006-09-07 | 2006-09-07 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof |
PCT/EP2007/059310 WO2008028934A1 (en) | 2006-09-06 | 2007-09-06 | Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20091239L true NO20091239L (no) | 2009-06-10 |
Family
ID=41706619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091239A NO20091239L (no) | 2006-09-06 | 2009-03-25 | Konjugater av disorazoler og deres derivater med celle bindingsmolekyler, nye disorazol derivater, fremgangsmate for fremstilling og anvendelse derav |
Country Status (5)
Country | Link |
---|---|
JP (1) | JP5340155B2 (no) |
HK (1) | HK1134812A1 (no) |
HR (1) | HRP20160631T1 (no) |
IL (1) | IL197127A (no) |
NO (1) | NO20091239L (no) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2895284A1 (en) * | 2013-02-07 | 2014-08-14 | Immunomedics, Inc. | Pro-drug form (p2pdox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843903A (en) * | 1995-11-27 | 1998-12-01 | The Administrators Of The Tulane Educational Fund | Targeted cytotoxic anthracycline analogs |
AU4267700A (en) * | 2000-01-13 | 2001-07-19 | Academia Sinica | Application of somatostatin analogs to specific delivery of anti-tumor drugs into tumor cells |
EP1536789A1 (de) * | 2002-08-24 | 2005-06-08 | Zentaris GmbH | Arzneimittel enthaltend disorale und ihre derivate und deren anwendung zur behandlung gutartiger und bösartiger tumorerkrankngen |
US7517903B2 (en) * | 2004-05-19 | 2009-04-14 | Medarex, Inc. | Cytotoxic compounds and conjugates |
EP1743897A1 (en) * | 2005-07-15 | 2007-01-17 | Gesellschaft für Biotechnologische Forschung mbH | Biologically active compounds obtainable from Sorangium cellulosum |
-
2007
- 2007-09-06 JP JP2009527139A patent/JP5340155B2/ja not_active Expired - Fee Related
-
2009
- 2009-02-19 IL IL197127A patent/IL197127A/en not_active IP Right Cessation
- 2009-03-25 NO NO20091239A patent/NO20091239L/no not_active Application Discontinuation
- 2009-12-18 HK HK09111963.1A patent/HK1134812A1/xx not_active IP Right Cessation
-
2016
- 2016-06-08 HR HRP20160631TT patent/HRP20160631T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
IL197127A0 (en) | 2009-11-18 |
JP2010502673A (ja) | 2010-01-28 |
IL197127A (en) | 2016-06-30 |
JP5340155B2 (ja) | 2013-11-13 |
HK1134812A1 (en) | 2010-05-14 |
HRP20160631T1 (hr) | 2016-07-15 |
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Legal Events
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RE | Reestablishment of rights (par. 72 patents act) | ||
FC2A | Withdrawal, rejection or dismissal of laid open patent application |