NO20090415L - JAK inhibitorer for behandling av myeloproliferative forstyrrelser - Google Patents
JAK inhibitorer for behandling av myeloproliferative forstyrrelserInfo
- Publication number
- NO20090415L NO20090415L NO20090415A NO20090415A NO20090415L NO 20090415 L NO20090415 L NO 20090415L NO 20090415 A NO20090415 A NO 20090415A NO 20090415 A NO20090415 A NO 20090415A NO 20090415 L NO20090415 L NO 20090415L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- myeloproliferative disorders
- jak inhibitors
- mammal
- condensed pyrrolocarbazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83262706P | 2006-07-21 | 2006-07-21 | |
US11/880,063 US20080021013A1 (en) | 2006-07-21 | 2007-07-19 | JAK inhibitors for treatment of myeloproliferative disorders |
PCT/US2007/016513 WO2008011174A2 (en) | 2006-07-21 | 2007-07-20 | Jak inhibitors for treatment of myeloproliferative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090415L true NO20090415L (no) | 2009-02-20 |
Family
ID=38814536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090415A NO20090415L (no) | 2006-07-21 | 2009-01-28 | JAK inhibitorer for behandling av myeloproliferative forstyrrelser |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080021013A1 (ja) |
EP (1) | EP2046340B1 (ja) |
JP (1) | JP5340931B2 (ja) |
KR (1) | KR101399180B1 (ja) |
AU (1) | AU2007275562B2 (ja) |
BR (1) | BRPI0715196A2 (ja) |
CA (1) | CA2658192C (ja) |
ES (1) | ES2437317T3 (ja) |
HK (1) | HK1127301A1 (ja) |
IL (1) | IL196517A (ja) |
MX (1) | MX2009000713A (ja) |
NO (1) | NO20090415L (ja) |
NZ (1) | NZ574212A (ja) |
WO (1) | WO2008011174A2 (ja) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR122021011788B1 (pt) * | 2005-11-01 | 2022-01-25 | Impact Biomedicines, Inc | Inibidores de biaril meta pirimidina de cinases, composição farmacêutica e processo para preparar uma composição farmacêutica |
US8604042B2 (en) * | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
US8133900B2 (en) * | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
US8460240B2 (en) * | 2006-08-07 | 2013-06-11 | W. L. Gore & Associates, Inc. | Inflatable toroidal-shaped balloons |
US20080125711A1 (en) * | 2006-08-07 | 2008-05-29 | Alpini Alfred A | Catheter balloons with integrated non-distensible seals |
WO2012060847A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
CA2856722C (en) | 2011-11-30 | 2022-11-22 | Emory University | Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections |
WO2014013014A1 (en) | 2012-07-18 | 2014-01-23 | Fundació Privada Centre De Regulació Genòmica (Crg) | Jak inhibitors for activation of epidermal stem cell populations |
DK3456333T3 (da) | 2012-12-07 | 2020-05-18 | Geron Corp | Anvendelse af telomeraseinhibitor imetelstat til behandling af myelodysplastisk syndrom |
WO2018041989A1 (en) | 2016-09-02 | 2018-03-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating refractory celiac disease type 2 |
US20220177978A1 (en) | 2019-04-02 | 2022-06-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
US20220202820A1 (en) | 2019-04-16 | 2022-06-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of jak inhibitors for the treatment of painful conditions involving nav1.7 channels |
US11691971B2 (en) | 2020-06-19 | 2023-07-04 | Incyte Corporation | Naphthyridinone compounds as JAK2 V617F inhibitors |
US11753413B2 (en) | 2020-06-19 | 2023-09-12 | Incyte Corporation | Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors |
TW202216713A (zh) | 2020-07-02 | 2022-05-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
US11767323B2 (en) | 2020-07-02 | 2023-09-26 | Incyte Corporation | Tricyclic pyridone compounds as JAK2 V617F inhibitors |
WO2022046989A1 (en) | 2020-08-27 | 2022-03-03 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
US11958861B2 (en) | 2021-02-25 | 2024-04-16 | Incyte Corporation | Spirocyclic lactams as JAK2 V617F inhibitors |
TW202337453A (zh) | 2022-03-17 | 2023-10-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
WO2023222565A1 (en) | 2022-05-16 | 2023-11-23 | Institut National de la Santé et de la Recherche Médicale | Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0303697B1 (en) * | 1987-03-09 | 1997-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance k-252 |
US5756494A (en) * | 1992-07-24 | 1998-05-26 | Cephalon, Inc. | Protein kinase inhibitors for treatment of neurological disorders |
EP0839814A3 (en) * | 1993-05-28 | 1998-09-16 | Cephalon, Inc. | Indolocarbazole derivatives and their use for the treatment of prostate gland disorders |
US5468872A (en) * | 1993-09-16 | 1995-11-21 | Cephalon, Inc. | K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders |
US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5808060A (en) * | 1995-12-11 | 1998-09-15 | Cephalon, Inc. | Fused isoindolones |
UA67725C2 (en) * | 1996-06-03 | 2004-07-15 | Cephalon Inc | K-252a derivatives and a method for improvement of functioning and cell survival enhancement |
NZ502646A (en) * | 1997-08-15 | 2002-04-26 | Cephalon Inc | A synergistic combination of tyrosine kinase inhibitors and chemical castration agents |
DE69812177T2 (de) * | 1997-12-31 | 2004-01-15 | Cephalon Inc | 3'-epi k-252a derivate |
US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
US6841567B1 (en) * | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
US6399780B1 (en) * | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
US6630500B2 (en) * | 2000-08-25 | 2003-10-07 | Cephalon, Inc. | Selected fused pyrrolocarbazoles |
US20040246627A1 (en) * | 2003-06-06 | 2004-12-09 | Durrum Thomas M. | Disc drive pivot bearing assembly |
US20050153990A1 (en) * | 2003-12-22 | 2005-07-14 | Watkins William J. | Phosphonate substituted kinase inhibitors |
US20060281700A1 (en) * | 2005-06-10 | 2006-12-14 | Baumann Christian A | Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators |
JP5249772B2 (ja) * | 2005-11-22 | 2013-07-31 | メルク・シャープ・アンド・ドーム・コーポレーション | キナーゼの阻害剤として有用な三環式化合物 |
CA2631641A1 (en) * | 2005-12-09 | 2007-06-21 | Abbott Laboratories | Lestaurtinib crystalline form 1, crystalline lestaurimib anhydrate and amorphous lestaurimib |
-
2007
- 2007-07-19 US US11/880,063 patent/US20080021013A1/en not_active Abandoned
- 2007-07-20 ES ES07836181.3T patent/ES2437317T3/es active Active
- 2007-07-20 WO PCT/US2007/016513 patent/WO2008011174A2/en active Application Filing
- 2007-07-20 MX MX2009000713A patent/MX2009000713A/es active IP Right Grant
- 2007-07-20 JP JP2009521782A patent/JP5340931B2/ja not_active Expired - Fee Related
- 2007-07-20 KR KR1020097003475A patent/KR101399180B1/ko not_active IP Right Cessation
- 2007-07-20 EP EP07836181.3A patent/EP2046340B1/en not_active Not-in-force
- 2007-07-20 BR BRPI0715196-9A patent/BRPI0715196A2/pt not_active IP Right Cessation
- 2007-07-20 CA CA2658192A patent/CA2658192C/en not_active Expired - Fee Related
- 2007-07-20 NZ NZ574212A patent/NZ574212A/en unknown
- 2007-07-20 AU AU2007275562A patent/AU2007275562B2/en not_active Ceased
-
2009
- 2009-01-14 IL IL196517A patent/IL196517A/en not_active IP Right Cessation
- 2009-01-28 NO NO20090415A patent/NO20090415L/no not_active Application Discontinuation
- 2009-08-07 HK HK09107276.1A patent/HK1127301A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1127301A1 (en) | 2009-09-25 |
EP2046340B1 (en) | 2013-09-04 |
KR20090035596A (ko) | 2009-04-09 |
CA2658192A1 (en) | 2008-01-24 |
NZ574212A (en) | 2011-12-22 |
CA2658192C (en) | 2016-05-24 |
JP5340931B2 (ja) | 2013-11-13 |
JP2009544700A (ja) | 2009-12-17 |
IL196517A0 (en) | 2009-11-18 |
WO2008011174A2 (en) | 2008-01-24 |
BRPI0715196A2 (pt) | 2013-11-12 |
US20080021013A1 (en) | 2008-01-24 |
IL196517A (en) | 2015-08-31 |
AU2007275562A1 (en) | 2008-01-24 |
AU2007275562B2 (en) | 2013-10-31 |
EP2046340A2 (en) | 2009-04-15 |
KR101399180B1 (ko) | 2014-05-27 |
MX2009000713A (es) | 2009-03-04 |
ES2437317T3 (es) | 2014-01-10 |
WO2008011174A3 (en) | 2008-03-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |