NO20084993L - Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produktene - Google Patents
Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produkteneInfo
- Publication number
- NO20084993L NO20084993L NO20084993A NO20084993A NO20084993L NO 20084993 L NO20084993 L NO 20084993L NO 20084993 A NO20084993 A NO 20084993A NO 20084993 A NO20084993 A NO 20084993A NO 20084993 L NO20084993 L NO 20084993L
- Authority
- NO
- Norway
- Prior art keywords
- taste
- genes
- methods
- umami
- bitter
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 13
- 235000019640 taste Nutrition 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 6
- 235000019608 salt taste sensations Nutrition 0.000 title abstract 4
- 108091005708 gustatory receptors Proteins 0.000 title abstract 2
- 235000019583 umami taste Nutrition 0.000 abstract 5
- 210000004027 cell Anatomy 0.000 abstract 4
- 235000009508 confectionery Nutrition 0.000 abstract 4
- 230000008447 perception Effects 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 2
- 230000001079 digestive effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000019634 flavors Nutrition 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- 229940124606 potential therapeutic agent Drugs 0.000 abstract 2
- 208000010470 Ageusia Diseases 0.000 abstract 1
- 101710112752 Cytotoxin Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 235000019647 acidic taste Nutrition 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 230000003822 cell turnover Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000012696 congenital leptin deficiency Diseases 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000002619 cytotoxin Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000010643 digestive system disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000001943 fluorescence-activated cell sorting Methods 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000003832 immune regulation Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 208000001022 morbid obesity Diseases 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000010187 selection method Methods 0.000 abstract 1
- 230000014860 sensory perception of taste Effects 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 235000019605 sweet taste sensations Nutrition 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 235000019607 umami taste sensations Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81176306P | 2006-06-08 | 2006-06-08 | |
| US83119906P | 2006-07-17 | 2006-07-17 | |
| US84899506P | 2006-10-04 | 2006-10-04 | |
| US86617806P | 2006-11-16 | 2006-11-16 | |
| PCT/US2007/013502 WO2007146120A2 (en) | 2006-06-08 | 2007-06-08 | Rationale, methods, and assays for identifying novel taste cell genes and salty taste receptor targets and assays using these identified genes or gene products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084993L true NO20084993L (no) | 2008-11-28 |
Family
ID=38832404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084993A NO20084993L (no) | 2006-06-08 | 2008-11-28 | Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produktene |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080261824A1 (https=) |
| EP (1) | EP2024518A4 (https=) |
| JP (1) | JP2009539377A (https=) |
| AU (1) | AU2007258511A1 (https=) |
| CA (1) | CA2654552A1 (https=) |
| IL (1) | IL195205A0 (https=) |
| MX (1) | MX2008015314A (https=) |
| NO (1) | NO20084993L (https=) |
| TW (1) | TW200813232A (https=) |
| WO (1) | WO2007146120A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10078087B2 (en) | 2001-05-01 | 2018-09-18 | Senomyx, Inc. | Assays and enhancers of the human delta ENaC sodium channel |
| CN1842709A (zh) | 2003-07-10 | 2006-10-04 | 塞诺米克斯公司 | 使用表达人的ENaC的卵母细胞的改进的电生理测定法和用于在使用膜电位报告染料的测定中提高ENaC增强子功效的PHENAMIL的用途 |
| WO2008051447A2 (en) * | 2006-10-19 | 2008-05-02 | Monell Chemical Senses Center | Human salty taste receptor and methods of modulating salty taste perception |
| US7932058B2 (en) | 2007-06-08 | 2011-04-26 | Senomyx, Inc. | Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays |
| US20090210953A1 (en) * | 2007-06-08 | 2009-08-20 | Bryan Moyer | Identification of TRPML3 (MCOLN3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone, and/or vasopressin production or release |
| WO2010065863A2 (en) * | 2008-12-05 | 2010-06-10 | Senomyx, Inc. | Assays for identifying genes encoding salty taste receptors and modulators |
| WO2010144773A1 (en) * | 2009-06-12 | 2010-12-16 | Monell Chemical Senses Center | Stg promoter and its use as a marker for taste and oocyte cells |
| SG175260A1 (en) | 2009-09-29 | 2011-11-28 | Ajinomoto Kk | Method for screening for salty taste control substance |
| JP5627479B2 (ja) * | 2011-01-24 | 2014-11-19 | 日清食品ホールディングス株式会社 | Ｓｋｎ−１ａ／ｉノックアウトマウスを用いた味蕾細胞マーカー分子の探索方法 |
| US12551526B2 (en) | 2015-04-22 | 2026-02-17 | Cedars-Sinai Medical Center | Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes |
| EP3733864B1 (en) * | 2017-12-28 | 2025-02-26 | Nissin Foods Holdings Co., Ltd. | Method for screening saltiness enhancer using saltiness receptor |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750339A (en) * | 1994-11-30 | 1998-05-12 | Thomas Jefferson University | Methods for identifying fetal cells |
| US7041448B2 (en) * | 2000-08-18 | 2006-05-09 | The ML4 Foundation | Gene encoding a new TRP channel is mutated in mucolipidosis IV |
| US20020164645A1 (en) * | 2000-12-29 | 2002-11-07 | The Regents Of The University Of California | Assays for taste receptor cell specific ion channel |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| EP1572871A4 (en) * | 2001-04-20 | 2007-11-14 | Sinai School Medicine | T1R3, A NEW TASTE RECEPTOR |
| WO2003004992A2 (en) * | 2001-07-03 | 2003-01-16 | The Regents Of The University Of California | Mammalian sweet and amino acid heterodimeric taste receptors |
| DE10155130A1 (de) * | 2001-11-12 | 2003-05-22 | Max Delbrueck Centrum | Verfahren zur Isolierung von Neuronen |
| US20050266442A1 (en) * | 2004-03-25 | 2005-12-01 | Rachel Squillace | Immortalized human Tuberous Sclerosis null angiomyolipoma cell and method of use thereof |
-
2007
- 2007-06-08 AU AU2007258511A patent/AU2007258511A1/en not_active Abandoned
- 2007-06-08 US US11/808,356 patent/US20080261824A1/en not_active Abandoned
- 2007-06-08 WO PCT/US2007/013502 patent/WO2007146120A2/en not_active Ceased
- 2007-06-08 JP JP2009514392A patent/JP2009539377A/ja not_active Abandoned
- 2007-06-08 MX MX2008015314A patent/MX2008015314A/es unknown
- 2007-06-08 TW TW096120717A patent/TW200813232A/zh unknown
- 2007-06-08 CA CA002654552A patent/CA2654552A1/en not_active Abandoned
- 2007-06-08 EP EP07809397A patent/EP2024518A4/en not_active Withdrawn
-
2008
- 2008-11-10 IL IL195205A patent/IL195205A0/en unknown
- 2008-11-28 NO NO20084993A patent/NO20084993L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2024518A2 (en) | 2009-02-18 |
| AU2007258511A1 (en) | 2007-12-21 |
| WO2007146120A2 (en) | 2007-12-21 |
| MX2008015314A (es) | 2008-12-12 |
| EP2024518A4 (en) | 2010-05-26 |
| WO2007146120A3 (en) | 2008-12-04 |
| CA2654552A1 (en) | 2007-12-21 |
| TW200813232A (en) | 2008-03-16 |
| US20080261824A1 (en) | 2008-10-23 |
| IL195205A0 (en) | 2009-08-03 |
| JP2009539377A (ja) | 2009-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |