NO20081035L - Ikke-invasivt legemiddel-leveringssystem som anvender en fast sammensetning pa vevet i bakre segment av oyet - Google Patents

Ikke-invasivt legemiddel-leveringssystem som anvender en fast sammensetning pa vevet i bakre segment av oyet

Info

Publication number
NO20081035L
NO20081035L NO20081035A NO20081035A NO20081035L NO 20081035 L NO20081035 L NO 20081035L NO 20081035 A NO20081035 A NO 20081035A NO 20081035 A NO20081035 A NO 20081035A NO 20081035 L NO20081035 L NO 20081035L
Authority
NO
Norway
Prior art keywords
drug delivery
eye
delivery system
posterior segment
fixed tissue
Prior art date
Application number
NO20081035A
Other languages
English (en)
Inventor
Koumei Okabe
Fumitaka Tasaka
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of NO20081035L publication Critical patent/NO20081035L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

Foreliggende oppfinnelse tilveiebringer et legemiddelleveringssystem ved ikke-invasiv administrasjon, som er fordelaktig ved legemiddeloverføring til et vev i posteriørsegmentet til øyet via et lokalt øyevev. Ved administrasjon av en fast sammensetning som innbefatter et legemiddel og en mukoadhesiv substans som har en adhesjonsstyrke på fra 200 til 1000 g i konjunktivalsekken, kan et legemiddelsleveringssystem som er svært fordelaktig når det gjelder legemiddeloverføring til et vev i posteriørsegmentet til øyet via et lokalt øyevev konstrueres.
NO20081035A 2005-07-29 2008-02-27 Ikke-invasivt legemiddel-leveringssystem som anvender en fast sammensetning pa vevet i bakre segment av oyet NO20081035L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005221388 2005-07-29
PCT/JP2006/314989 WO2007013590A1 (ja) 2005-07-29 2006-07-28 固形組成物を用いた後眼部組織への非侵襲性ドラッグデリバリーシステム

Publications (1)

Publication Number Publication Date
NO20081035L true NO20081035L (no) 2008-04-16

Family

ID=37683477

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081035A NO20081035L (no) 2005-07-29 2008-02-27 Ikke-invasivt legemiddel-leveringssystem som anvender en fast sammensetning pa vevet i bakre segment av oyet

Country Status (8)

Country Link
US (1) US20090036552A1 (no)
EP (1) EP1930028A4 (no)
KR (1) KR101464003B1 (no)
CN (1) CN101232902B (no)
CA (1) CA2617040A1 (no)
NO (1) NO20081035L (no)
RU (1) RU2414193C2 (no)
WO (1) WO2007013590A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1835735B (zh) * 2003-08-20 2010-05-12 参天制药株式会社 微粒眼球筋膜下给药的药物释放系统
JP5886204B2 (ja) * 2009-10-30 2016-03-16 アトーン ファルマ、インコーポレイテッドＡｔｏｎ Ｐｈａｒｍａ，Ｉｎｃ． 眼内薬剤送達装置
US20120245505A1 (en) * 2009-12-16 2012-09-27 Robinson Michael R Intracameral devices for sustained delivery
US9694050B2 (en) 2012-10-21 2017-07-04 University Of Rochester THY1 (CD90) as a novel therapy to control adipose tissue accumulation
JP2021522309A (ja) * 2018-05-04 2021-08-30 フェネロン ホランド ホールディング ビー．ブイ． ヒアルロナンを可視化する為の可視化剤

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US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
NL188266C (nl) * 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4045558A (en) * 1975-10-08 1977-08-30 Merck & Co., Inc. Pilocarpine salts
EP0108661A1 (en) * 1982-10-04 1984-05-16 Merck & Co. Inc. Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
US4615697A (en) * 1983-11-14 1986-10-07 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
US4946859A (en) * 1989-07-31 1990-08-07 Merck & Co., Inc. 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide
FR2690846B1 (fr) * 1992-05-05 1995-07-07 Aiache Jean Marc Forme galenique pour administration oculaire et procede de preparation.
CA2142103C (en) * 1992-08-28 2003-07-08 Haim Aviv Submicron emulsions as ocular drug delivery vehicles
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
JP2002526403A (ja) * 1998-10-02 2002-08-20 スリーエム イノベイティブ プロパティズ カンパニー 粘膜を起点としたデリバリーシステムおよび動物への適用
AU1101501A (en) * 1999-10-27 2001-05-08 K-Quay Enterprises, Llc Methods and compositions for treatment of keratoconus using protease inhibitors
US7001615B1 (en) * 2001-12-07 2006-02-21 Alcon, Inc. Sustained release ophthalmic, otic and nasal suspension
FR2833493B1 (fr) * 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
KR20100102749A (ko) * 2002-02-22 2010-09-24 산텐 세이야꾸 가부시키가이샤 미립자 결막하 투여를 위한 약물 수송 시스템
US20050013845A1 (en) * 2002-11-12 2005-01-20 Warren Stephen L. Adhesive bioerodible ocular drug delivery system
JP2004196787A (ja) * 2002-12-04 2004-07-15 Santen Pharmaceut Co Ltd 結膜下デポによるドラッグデリバリーシステム
CN1835735B (zh) * 2003-08-20 2010-05-12 参天制药株式会社 微粒眼球筋膜下给药的药物释放系统
CA2598095A1 (en) * 2005-02-18 2009-08-24 Santen Pharmaceutical Co., Ltd. Method of relieving or avoiding side effect of steroid

Also Published As

Publication number Publication date
CN101232902B (zh) 2013-04-17
KR101464003B1 (ko) 2014-11-20
KR20080033285A (ko) 2008-04-16
US20090036552A1 (en) 2009-02-05
RU2414193C2 (ru) 2011-03-20
WO2007013590A1 (ja) 2007-02-01
RU2008107696A (ru) 2009-09-10
CN101232902A (zh) 2008-07-30
EP1930028A1 (en) 2008-06-11
EP1930028A4 (en) 2010-11-17
CA2617040A1 (en) 2007-02-01

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