NO20080304L - Behandlingsmetoder ved bruk av hydrokinon-ansamyciner - Google Patents
Behandlingsmetoder ved bruk av hydrokinon-ansamycinerInfo
- Publication number
- NO20080304L NO20080304L NO20080304A NO20080304A NO20080304L NO 20080304 L NO20080304 L NO 20080304L NO 20080304 A NO20080304 A NO 20080304A NO 20080304 A NO20080304 A NO 20080304A NO 20080304 L NO20080304 L NO 20080304L
- Authority
- NO
- Norway
- Prior art keywords
- benzoquinone
- hydroquinone
- treatment
- methods
- ansamycins
- Prior art date
Links
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 title abstract 5
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer metoder for behandling av hyperproliferative lidelser så som kreft ved administrering av hydrokinon-ansamycin forbindelser.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/180,314 US20060019941A1 (en) | 2003-12-23 | 2005-07-13 | Analogs of benzoquinone-containing ansamycins and methods of use thereof |
PCT/US2006/027113 WO2007009007A2 (en) | 2005-07-13 | 2006-07-13 | Methods of treatment using hydroquinone ansamycins |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20080304L true NO20080304L (no) | 2008-02-29 |
Family
ID=37637939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080304A NO20080304L (no) | 2005-07-13 | 2008-01-16 | Behandlingsmetoder ved bruk av hydrokinon-ansamyciner |
Country Status (16)
Country | Link |
---|---|
US (1) | US20060019941A1 (no) |
EP (1) | EP1904057B1 (no) |
JP (1) | JP2009501234A (no) |
KR (1) | KR20080030093A (no) |
CN (1) | CN101267816A (no) |
AT (1) | ATE451919T1 (no) |
AU (1) | AU2006268196A1 (no) |
BR (1) | BRPI0612870A2 (no) |
CA (1) | CA2612506A1 (no) |
DE (1) | DE602006011161D1 (no) |
ES (1) | ES2337397T3 (no) |
IL (1) | IL188355A0 (no) |
MX (1) | MX2007016469A (no) |
NO (1) | NO20080304L (no) |
WO (1) | WO2007009007A2 (no) |
ZA (1) | ZA200800906B (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101154351B1 (ko) | 2003-12-23 | 2012-06-15 | 인피니티 디스커버리, 인코포레이티드 | 암 치료를 위한 벤조퀴논-함유 안사마이신의 유사체 |
WO2006098761A2 (en) * | 2005-03-11 | 2006-09-21 | The Regents Of The University Of Colorado | Hsp90 inhibitors, methods of making and uses therefor |
WO2007002093A2 (en) * | 2005-06-21 | 2007-01-04 | Infinity Discovery, Inc. | Ansamycin formulations and methods of use thereof |
FR2907453B1 (fr) * | 2006-10-24 | 2008-12-26 | Sanofi Aventis Sa | Nouveaux derives du fluorene,compositions les contenant et utilisation |
PE20081506A1 (es) | 2006-12-12 | 2008-12-09 | Infinity Discovery Inc | Formulaciones de ansamicina |
US20080255080A1 (en) * | 2007-04-12 | 2008-10-16 | Wright James L | Hydroquinone Ansamycin Formulations |
US8551964B2 (en) | 2007-08-23 | 2013-10-08 | The Regents Of The University Of Colorado | Hsp90 inhibitors with modified toxicity |
US20090258869A1 (en) * | 2008-02-08 | 2009-10-15 | The Regents Of The University Of California | Methods and compounds for treatment or prevention of substance-related disorders |
ES2616231T3 (es) * | 2008-08-21 | 2017-06-12 | Immunogenics Llc | Formulación para administración oral de proteínas |
WO2010045442A1 (en) * | 2008-10-15 | 2010-04-22 | Infinity Discovery, Inc. | Ansamycin hydroquinone compositions |
US20120108563A1 (en) * | 2009-05-19 | 2012-05-03 | Infinity Pharmaceuticals, Inc. | Methods Of Treating Liposarcoma |
AR077405A1 (es) | 2009-07-10 | 2011-08-24 | Sanofi Aventis | Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer |
FR2949467B1 (fr) | 2009-09-03 | 2011-11-25 | Sanofi Aventis | Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation |
US8945627B2 (en) | 2011-05-05 | 2015-02-03 | Wisconsin Alumni Research Foundation | Micelles for the solubilization of gossypol |
US9603829B2 (en) | 2011-11-14 | 2017-03-28 | The Regents Of The University Of Colorado, A Body Corporate | HSP90 inhibitors with modified toxicity |
US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
KR102369736B1 (ko) | 2014-05-01 | 2022-03-02 | 아이오니스 파마수티컬즈, 인코포레이티드 | 보체 인자 b 발현을 조절하기 위한 조성물 및 방법 |
CN114259564B (zh) * | 2021-11-30 | 2023-03-14 | 清华大学 | Hsp90抑制剂阻碍stat3线粒体转运和治疗哮喘的新应用 |
CN115227692A (zh) * | 2022-09-05 | 2022-10-25 | 中国医学科学院基础医学研究所 | Reblastatin在制备治疗慢性惊厥的药物中的用途 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4261989A (en) * | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
GB2106111B (en) * | 1981-09-17 | 1985-11-06 | Takeda Chemical Industries Ltd | Macbecin derivatives and their production |
US4762857A (en) * | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
WO1993014215A1 (en) * | 1992-01-06 | 1993-07-22 | Pfizer Inc. | Process and uses for 4,5-dihydrogeldanamycin and its hydroquinone |
US5387584A (en) * | 1993-04-07 | 1995-02-07 | Pfizer Inc. | Bicyclic ansamycins |
JP2794342B2 (ja) * | 1993-06-29 | 1998-09-03 | ファイザー・インク. | 抗癌遺伝子剤および抗癌剤としてのアンサマイシン誘導体 |
US5932566A (en) * | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
EP1373215B1 (en) * | 2001-03-30 | 2006-07-26 | THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH | Geldanamycin derivatives useful for treating cancer |
WO2003013430A2 (en) * | 2001-08-06 | 2003-02-20 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
WO2003066005A2 (en) * | 2002-02-08 | 2003-08-14 | Conforma Therapeutics Corporation | Ansamycins having improved pharmacological and biological properties |
KR101154351B1 (ko) * | 2003-12-23 | 2012-06-15 | 인피니티 디스커버리, 인코포레이티드 | 암 치료를 위한 벤조퀴논-함유 안사마이신의 유사체 |
WO2006098761A2 (en) * | 2005-03-11 | 2006-09-21 | The Regents Of The University Of Colorado | Hsp90 inhibitors, methods of making and uses therefor |
-
2005
- 2005-07-13 US US11/180,314 patent/US20060019941A1/en not_active Abandoned
-
2006
- 2006-07-13 EP EP06787067A patent/EP1904057B1/en active Active
- 2006-07-13 AT AT06787067T patent/ATE451919T1/de not_active IP Right Cessation
- 2006-07-13 AU AU2006268196A patent/AU2006268196A1/en not_active Abandoned
- 2006-07-13 ZA ZA200800906A patent/ZA200800906B/xx unknown
- 2006-07-13 ES ES06787067T patent/ES2337397T3/es active Active
- 2006-07-13 MX MX2007016469A patent/MX2007016469A/es not_active Application Discontinuation
- 2006-07-13 CA CA002612506A patent/CA2612506A1/en not_active Abandoned
- 2006-07-13 WO PCT/US2006/027113 patent/WO2007009007A2/en active Application Filing
- 2006-07-13 CN CNA2006800335526A patent/CN101267816A/zh active Pending
- 2006-07-13 BR BRPI0612870-0A patent/BRPI0612870A2/pt not_active IP Right Cessation
- 2006-07-13 JP JP2008521582A patent/JP2009501234A/ja active Pending
- 2006-07-13 DE DE602006011161T patent/DE602006011161D1/de active Active
- 2006-07-13 KR KR1020087003410A patent/KR20080030093A/ko not_active Application Discontinuation
-
2007
- 2007-12-24 IL IL188355A patent/IL188355A0/en unknown
-
2008
- 2008-01-16 NO NO20080304A patent/NO20080304L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0612870A2 (pt) | 2010-11-30 |
DE602006011161D1 (de) | 2010-01-28 |
WO2007009007A2 (en) | 2007-01-18 |
WO2007009007A3 (en) | 2007-05-03 |
EP1904057B1 (en) | 2009-12-16 |
CN101267816A (zh) | 2008-09-17 |
EP1904057A2 (en) | 2008-04-02 |
ZA200800906B (en) | 2009-07-29 |
JP2009501234A (ja) | 2009-01-15 |
US20060019941A1 (en) | 2006-01-26 |
IL188355A0 (en) | 2008-08-07 |
ES2337397T3 (es) | 2010-04-23 |
ATE451919T1 (de) | 2010-01-15 |
AU2006268196A1 (en) | 2007-01-18 |
KR20080030093A (ko) | 2008-04-03 |
MX2007016469A (es) | 2008-04-22 |
CA2612506A1 (en) | 2007-01-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20080304L (no) | Behandlingsmetoder ved bruk av hydrokinon-ansamyciner | |
NO20062707L (no) | Analoger av benzokinon-inneholdende ansamyciner for behandling av kreft | |
CY1109104T1 (el) | 1,2,3,4 τετρα-υποκατεστημενη ινδολη για την αντιμετωπιση ασθενειων του αναπνευστικου | |
EA201071243A1 (ru) | Комбинированные композиции для лечения болезни альцгеймера и родственных заболеваний зонизамидом и акампросатом | |
WO2008024304A3 (en) | Compounds for treatment of proliferative disorders | |
UA100983C2 (ru) | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты | |
HK1136283A1 (en) | Compounds for the prevention and treatment of cardiovascular diseases | |
TW200730515A (en) | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | |
EA201070988A1 (ru) | Противовирусные терапевтические средства | |
TN2010000125A1 (en) | Substituted biphenyl gpr40 modulators | |
EA200700909A1 (ru) | Азаиндолкарбоксамиды | |
BRPI0507968A (pt) | oxidação de compostos orgánicos a ph alto | |
MX2008010671A (es) | Derivados de cinolina como inhibidores de fosfodiesterasa 10. | |
EA201001286A1 (ru) | Комбинированное применение 25-гидроксивитамина d3 и витамина d3 для повышения плотности минерального вещества костей и для лечения остеопороза | |
EA200802223A1 (ru) | 1,5-дифенилпиразолы ii в качестве ингибиторов hsp90 | |
BR112015012051A2 (pt) | composições e métodos para modulação de expressão de fgfr3 | |
BRPI0911907B8 (pt) | processo para produzir uma composição contendo triptofano e composição proteica contendo triptofano | |
TW200728258A (en) | Novel compounds | |
EA201190004A1 (ru) | Конденсированные имидазол карбоксамиды в качестве модуляторов trpv3 | |
IN2014CN02273A (no) | ||
MX2010002042A (es) | Derivados de 1,3-dihidroisoindol. | |
TW200633977A (en) | Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives | |
ES2333026T3 (es) | Derivados de ciclohexil-1,4-diamina sustituidos. | |
EA201001586A1 (ru) | Соединения и композиции в качестве ингибиторов itpkb | |
NO20074252L (no) | Forbindelser og anvendelser derav |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |