NO20074584L - Peptidomimetiske forbindelser og fremstilling av biologisk aktive derivater - Google Patents
Peptidomimetiske forbindelser og fremstilling av biologisk aktive derivaterInfo
- Publication number
- NO20074584L NO20074584L NO20074584A NO20074584A NO20074584L NO 20074584 L NO20074584 L NO 20074584L NO 20074584 A NO20074584 A NO 20074584A NO 20074584 A NO20074584 A NO 20074584A NO 20074584 L NO20074584 L NO 20074584L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- biologically active
- peptidomimetic compounds
- active derivatives
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Oppfinnelsen angår nye sykliske peptidomimetiske forbindelser representert ved formel I inneholdende sekvensen RGD for fremstilling av passende funksjonaliserte antagonister til ?v?3- og ?v?5-integriner, og ment for eksempel for behandling av endrede angiogene fenomener eller for fremstilling av diagnostisk anvendelige forbindelser. (I)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000328A ITMI20050328A1 (it) | 2005-03-03 | 2005-03-03 | Composti peptidomimetrici e preparazione di derivati biologicamente attivi |
PCT/IB2006/000460 WO2006092722A1 (en) | 2005-03-03 | 2006-03-03 | Peptidomimetic compounds and preparation of biologically active derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074584L true NO20074584L (no) | 2007-09-27 |
Family
ID=36570882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074584A NO20074584L (no) | 2005-03-03 | 2007-09-11 | Peptidomimetiske forbindelser og fremstilling av biologisk aktive derivater |
Country Status (17)
Country | Link |
---|---|
US (3) | US8636977B2 (no) |
EP (2) | EP1853603A1 (no) |
JP (1) | JP2008531677A (no) |
KR (1) | KR20080009681A (no) |
CN (1) | CN101184755A (no) |
AU (1) | AU2006219674A1 (no) |
CA (1) | CA2599876A1 (no) |
DK (1) | DK1853605T3 (no) |
ES (1) | ES2525374T3 (no) |
IL (1) | IL185353A0 (no) |
IT (1) | ITMI20050328A1 (no) |
NO (1) | NO20074584L (no) |
PL (1) | PL1853605T3 (no) |
PT (1) | PT1853605E (no) |
RU (1) | RU2007136535A (no) |
SI (1) | SI1853605T1 (no) |
WO (2) | WO2006092722A1 (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20050328A1 (it) | 2005-03-03 | 2006-09-04 | Univ Degli Studi Milano | Composti peptidomimetrici e preparazione di derivati biologicamente attivi |
US8986650B2 (en) | 2005-10-07 | 2015-03-24 | Guerbet | Complex folate-NOTA-Ga68 |
EP1940841B9 (fr) | 2005-10-07 | 2017-04-19 | Guerbet | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
US8242105B2 (en) | 2006-09-25 | 2012-08-14 | Forschungsverbund Berlin E.V. | Structural mimetics of proline-rich peptides and the pharmaceutical use thereof |
EP1961759A1 (en) * | 2007-02-21 | 2008-08-27 | Universita'degli Studi Di Milano | Integrin targeted cyclopeptide ligands, their preparation and use |
JP2010526091A (ja) * | 2007-04-30 | 2010-07-29 | インテザイン テクノロジーズ, インコーポレイテッド | 癌の処置のための生物学的な標的基の改変 |
EP2065058A1 (en) * | 2007-11-28 | 2009-06-03 | Koninklijke Philips Electronics N.V. | Non-spherical contrast agents for CEST MRI based on bulk magnetic susceptibility effect |
EP2127640A1 (en) | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Azide modified proteins |
FR2942227B1 (fr) | 2009-02-13 | 2011-04-15 | Guerbet Sa | Utilisation de tampons pour la complexation de radionucleides |
US8920775B2 (en) | 2009-07-17 | 2014-12-30 | Technical University Of Denmark | Loading technique for preparing radionuclide containing nanoparticles |
GB0922014D0 (en) * | 2009-12-17 | 2010-02-03 | Ge Healthcare Ltd | Novel integrin binders |
FR2968662B1 (fr) | 2010-12-10 | 2013-11-22 | Roussy Inst Gustave | Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation |
AU2011344865B2 (en) | 2010-12-14 | 2017-03-09 | Rigshospitalet | Entrapment of radionuclides in nanoparticle compositions |
EP2864347B1 (en) * | 2012-06-22 | 2020-10-28 | Mimetogen Pharmaceuticals, Inc. | Synthesis of beta-turn peptidomimetic cyclic compounds |
CN107206108B (zh) | 2014-12-19 | 2021-08-31 | 伯拉考成像股份公司 | 术中成像 |
KR102479601B1 (ko) | 2015-12-21 | 2022-12-22 | 텍사스 테크 유니버시티 시스템 | 용액상 gap 펩타이드 합성을 위한 시스템 및 방법 |
CA3044526A1 (en) | 2016-12-07 | 2018-06-14 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
CN116712540A (zh) | 2016-12-14 | 2023-09-08 | 比奥拉治疗股份有限公司 | 使用整联蛋白抑制剂治疗胃肠道疾病 |
US10870649B2 (en) * | 2017-04-13 | 2020-12-22 | Bracco Imaging Spa | Synthesis of NIR fluorescent probe |
EP3720854B1 (en) * | 2017-12-06 | 2021-04-21 | Bracco Imaging SpA | Solid phase synthesis of nir fluorescent probe |
WO2019231760A1 (en) * | 2018-05-31 | 2019-12-05 | Gap Peptides Llc | Method for solution-phase peptide synthesis and protecting strategies therefore |
US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
EP3883636A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
US11827660B2 (en) | 2019-02-01 | 2023-11-28 | Sederma | Synthesis strategy for gap protecting group |
EP4309722A2 (en) | 2019-12-13 | 2024-01-24 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268486A (en) | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
DE4445065A1 (de) | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
DE69702912T2 (de) | 1996-07-05 | 2001-04-05 | Edouard Pfister | Uhrwerk |
CA2265484C (en) | 1996-09-10 | 2008-12-02 | The Burnham Institute | Tumor homing molecules, conjugates derived therefrom, and methods of using same |
US6261537B1 (en) * | 1996-10-28 | 2001-07-17 | Nycomed Imaging As | Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors |
ITRM20020402A1 (it) | 2002-07-29 | 2004-01-29 | Sigma Tau Ind Farmaceuti | Derivati fluoro-alchil-ciclopeptidi ad attivita' anti-integrine. |
ITMI20031476A1 (it) * | 2003-07-18 | 2005-01-19 | Univ Degli Studi Milano | Composti peptido-mimetici a struttura azabicicloalcanica comprendenti la sequenza rgd |
WO2005019247A2 (en) | 2003-08-15 | 2005-03-03 | Board Of Regents, The University Of Texas System | Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy |
ITMI20032102A1 (it) * | 2003-10-30 | 2005-04-30 | Univ Degli Studi Milano | Composti peptidomimetici, procedimento stereoselettivo per la loro preparazione, loro uso come intermedi di sintesi di derivati biologicamente attivi. |
JP5280683B2 (ja) | 2004-06-16 | 2013-09-04 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | ペプチド系化合物 |
ITMI20050328A1 (it) * | 2005-03-03 | 2006-09-04 | Univ Degli Studi Milano | Composti peptidomimetrici e preparazione di derivati biologicamente attivi |
EP1961759A1 (en) | 2007-02-21 | 2008-08-27 | Universita'degli Studi Di Milano | Integrin targeted cyclopeptide ligands, their preparation and use |
CN102264756B (zh) | 2008-10-23 | 2014-08-06 | 斯特巴生物技术有限公司 | 含rgd的拟肽和其用途 |
WO2010076334A2 (en) | 2008-12-31 | 2010-07-08 | Centre Leon Berard | Intraoperative diagnosis of primary tumors and secondary tumors or metastases |
EP2457593A1 (en) | 2010-11-08 | 2012-05-30 | Lykera Biomed S.A. | Cyclic RGD peptides of amino acids based on thiazoles or oxazoles as selective antagonists of the alpha-v beta-3 integrin |
-
2005
- 2005-03-03 IT IT000328A patent/ITMI20050328A1/it unknown
-
2006
- 2006-03-03 SI SI200631838T patent/SI1853605T1/sl unknown
- 2006-03-03 US US11/885,353 patent/US8636977B2/en active Active
- 2006-03-03 EP EP06710490A patent/EP1853603A1/en not_active Withdrawn
- 2006-03-03 DK DK06744433.1T patent/DK1853605T3/en active
- 2006-03-03 US US11/883,880 patent/US20080139461A1/en not_active Abandoned
- 2006-03-03 WO PCT/IB2006/000460 patent/WO2006092722A1/en active Application Filing
- 2006-03-03 PT PT67444331T patent/PT1853605E/pt unknown
- 2006-03-03 PL PL06744433T patent/PL1853605T3/pl unknown
- 2006-03-03 AU AU2006219674A patent/AU2006219674A1/en not_active Abandoned
- 2006-03-03 WO PCT/IB2006/000455 patent/WO2006095234A2/en active Application Filing
- 2006-03-03 EP EP06744433.1A patent/EP1853605B1/en active Active
- 2006-03-03 RU RU2007136535/04A patent/RU2007136535A/ru not_active Application Discontinuation
- 2006-03-03 ES ES06744433.1T patent/ES2525374T3/es active Active
- 2006-03-03 JP JP2007557619A patent/JP2008531677A/ja active Pending
- 2006-03-03 CA CA002599876A patent/CA2599876A1/en not_active Abandoned
- 2006-03-03 KR KR1020077022078A patent/KR20080009681A/ko not_active Application Discontinuation
- 2006-03-03 CN CNA200680013640XA patent/CN101184755A/zh active Pending
-
2007
- 2007-08-19 IL IL185353A patent/IL185353A0/en unknown
- 2007-09-11 NO NO20074584A patent/NO20074584L/no not_active Application Discontinuation
-
2014
- 2014-01-13 US US14/153,706 patent/US9409951B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20140178302A1 (en) | 2014-06-26 |
US9409951B2 (en) | 2016-08-09 |
DK1853605T3 (en) | 2014-12-15 |
WO2006092722A8 (en) | 2008-01-31 |
WO2006095234A3 (en) | 2006-12-07 |
JP2008531677A (ja) | 2008-08-14 |
RU2007136535A (ru) | 2009-04-10 |
US20080317668A1 (en) | 2008-12-25 |
EP1853605A2 (en) | 2007-11-14 |
CA2599876A1 (en) | 2006-09-08 |
ITMI20050328A1 (it) | 2006-09-04 |
US8636977B2 (en) | 2014-01-28 |
SI1853605T1 (sl) | 2014-12-31 |
AU2006219674A1 (en) | 2006-09-08 |
WO2006092722A1 (en) | 2006-09-08 |
ES2525374T3 (es) | 2014-12-23 |
PL1853605T3 (pl) | 2015-02-27 |
EP1853603A1 (en) | 2007-11-14 |
IL185353A0 (en) | 2008-02-09 |
PT1853605E (pt) | 2014-12-03 |
CN101184755A (zh) | 2008-05-21 |
US20080139461A1 (en) | 2008-06-12 |
EP1853605B1 (en) | 2014-09-10 |
WO2006095234A2 (en) | 2006-09-14 |
KR20080009681A (ko) | 2008-01-29 |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |