NO20072529L - Cytotoksisk utforming for kombinasjonsbehandling - Google Patents

Cytotoksisk utforming for kombinasjonsbehandling

Info

Publication number
NO20072529L
NO20072529L NO20072529A NO20072529A NO20072529L NO 20072529 L NO20072529 L NO 20072529L NO 20072529 A NO20072529 A NO 20072529A NO 20072529 A NO20072529 A NO 20072529A NO 20072529 L NO20072529 L NO 20072529L
Authority
NO
Norway
Prior art keywords
cytotoxic
design
combination therapy
methods
liposomes
Prior art date
Application number
NO20072529A
Other languages
English (en)
Inventor
Roy Larsen
Thora Johanna Jonasdottir
Original Assignee
Algeta Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Algeta Asa filed Critical Algeta Asa
Publication of NO20072529L publication Critical patent/NO20072529L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen gjelder cytotoksiske midler som omfatter liposomer, hvori liposomene omslutter en løsning som omfatter minst ett alfaemitterende radionuklid og minst ett annet terapeutisk middel, fortrinnsvis et kjemoterapeutisk middel. Oppfinnelsen tilveiebringer også fremgangsmåter for fremstilling av slike cytotoksiske midler, fremgangsmåter for behandling, fortrinnsvis kreftbehandling, som benytter midlene og fremgangsmåter for anvendelsen av dem for fremstilling av medikamenter.
NO20072529A 2004-10-22 2007-05-18 Cytotoksisk utforming for kombinasjonsbehandling NO20072529L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0423565.1A GB0423565D0 (en) 2004-10-22 2004-10-22 Formulation
PCT/GB2005/004074 WO2006043083A2 (en) 2004-10-22 2005-10-21 Liposomes enclosing a radionuclide and a cytotoxic agent for combination therapy

Publications (1)

Publication Number Publication Date
NO20072529L true NO20072529L (no) 2007-05-18

Family

ID=33485085

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072529A NO20072529L (no) 2004-10-22 2007-05-18 Cytotoksisk utforming for kombinasjonsbehandling

Country Status (17)

Country Link
US (1) US20080193374A1 (no)
EP (1) EP1812115B1 (no)
JP (1) JP5615483B2 (no)
KR (2) KR20130019029A (no)
CN (1) CN101060886A (no)
AU (1) AU2005297082B2 (no)
BR (1) BRPI0517006A (no)
CA (1) CA2583367C (no)
EA (1) EA011715B1 (no)
ES (1) ES2424844T3 (no)
GB (1) GB0423565D0 (no)
IL (1) IL182634A (no)
MX (1) MX2007004542A (no)
NO (1) NO20072529L (no)
NZ (1) NZ582713A (no)
WO (1) WO2006043083A2 (no)
ZA (1) ZA200704035B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE424221T1 (de) 2003-04-30 2009-03-15 Univ Ramot Verfahren und vorrichtung für strahlentherapie
WO2007008232A2 (en) * 2004-09-03 2007-01-18 Board Of Regents, The University Of Texas System Locoregional internal radionuclide ablation of abnormal tissues.
US20100015042A1 (en) * 2008-07-03 2010-01-21 Ramot At Tel Aviv University Ltd. Combine radiation therapy and chemotherapy for treating cancer
JP5872466B2 (ja) * 2009-07-17 2016-03-01 テクニカル ユニバーシティ オブ デンマークＴｅｃｈｎｉｃａｌ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｄｅｎｍａｒｋ 放射性核種含有ナノ粒子を製造するための封入方法
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
DK2651447T3 (en) 2010-12-14 2018-12-17 Univ Denmark Tech Dtu Capture of radionuclides in nanoparticle compositions
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation
WO2014039874A2 (en) * 2012-09-07 2014-03-13 Carnegie Mellon University Methods and materials for reducing reticuloendothelial system clearance of particles from a subject
WO2014095833A1 (en) * 2012-12-19 2014-06-26 Bayer Pharma Aktiengesellschaft Combination comprising radium-223 for the treatment of cancer
US9795621B2 (en) 2012-12-20 2017-10-24 Carnegie Mellon University Methods and materials for reducing organ transplant rejection or ischemic/reperfusion injury in a subject
EP3258917B1 (en) 2015-02-19 2022-12-21 Carnegie Mellon University Methods to reduce toxicities and to improve bioavailabilities of nanodrugs
DK3261681T3 (da) * 2015-02-26 2020-04-27 Sciencons AS Radiofarmaceutiske opløsninger med fordelagtige egenskaber
US9433690B1 (en) * 2015-02-26 2016-09-06 Sciencons AS Radiopharmaceutical solutions with advantageous properties
HUE034806T2 (en) * 2015-07-03 2018-02-28 Oncoinvent As Radiotherapy Particles and Suspensions
AU2018265386B2 (en) 2017-05-11 2020-07-23 Alpha Tau Medical Ltd. Polymer coatings for brachytherapy devices
JP2021519126A (ja) 2018-04-02 2021-08-10 アルファ タウ メディカル リミテッド 放射性核種の管理された放出
JP2023541635A (ja) * 2020-09-15 2023-10-03 オンコインベント アクスィエ セルスカプ Ｄｎａ修復阻害剤との組み合わせによる放射性核種療法での使用のためのラジウム２２４とプロジェニーとの調製
US11857803B2 (en) 2020-12-16 2024-01-02 Alpha Tau Medical Ltd. Diffusing alpha-emitter radiation therapy with enhanced beta treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
NO312708B1 (no) * 2000-02-21 2002-06-24 Anticancer Therapeutic Inv Sa Radioaktive liposomer til terapi
DE60135743D1 (de) * 2000-06-16 2008-10-23 Sloan Kettering Inst Cancer Liposomale einkapselung von alphastrahlern, und deren verwendung
US20040166060A1 (en) * 2000-06-16 2004-08-26 Sloan Kettering Institute For Cancer Research Liposomal encapsulation of alpha particle emittors and uses thereof
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
WO2004004635A2 (en) * 2002-07-02 2004-01-15 Board Of Regents, The University Of Texas System Radiolabeled compounds and liposomes and their methods of making and using the same
US7254229B2 (en) * 2003-03-07 2007-08-07 Legerity, Inc. Method and apparatus for an active impedance feedback
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
US20060228297A1 (en) * 2003-04-15 2006-10-12 Roy Larsen Thorium-227 for use in radiotherapy of soft tissue disease

Also Published As

Publication number Publication date
CN101060886A (zh) 2007-10-24
EP1812115B1 (en) 2013-05-15
US20080193374A1 (en) 2008-08-14
CA2583367C (en) 2014-09-16
GB0423565D0 (en) 2004-11-24
BRPI0517006A (pt) 2008-09-30
IL182634A (en) 2016-03-31
AU2005297082A1 (en) 2006-04-27
ZA200704035B (en) 2008-08-27
WO2006043083A2 (en) 2006-04-27
EA200700686A1 (ru) 2007-10-26
KR20130019029A (ko) 2013-02-25
IL182634A0 (en) 2007-07-24
KR20070108851A (ko) 2007-11-13
EP1812115A2 (en) 2007-08-01
JP5615483B2 (ja) 2014-10-29
WO2006043083A3 (en) 2007-01-04
NZ582713A (en) 2012-06-29
EA011715B1 (ru) 2009-04-28
JP2008517049A (ja) 2008-05-22
AU2005297082B2 (en) 2011-11-17
MX2007004542A (es) 2007-08-17
WO2006043083A8 (en) 2007-09-27
ES2424844T3 (es) 2013-10-09
CA2583367A1 (en) 2006-04-27

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application