NO20065319L - Piperidinderivater som modulatorer for kjemokinreseptor CCR5 - Google Patents

Piperidinderivater som modulatorer for kjemokinreseptor CCR5

Info

Publication number
NO20065319L
NO20065319L NO20065319A NO20065319A NO20065319L NO 20065319 L NO20065319 L NO 20065319L NO 20065319 A NO20065319 A NO 20065319A NO 20065319 A NO20065319 A NO 20065319A NO 20065319 L NO20065319 L NO 20065319L
Authority
NO
Norway
Prior art keywords
modulators
chemokine receptor
piperidine derivatives
receptor ccr5
ccr5
Prior art date
Application number
NO20065319A
Other languages
English (en)
Norwegian (no)
Inventor
Alan Faull
Howard Tucker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35197429&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20065319(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE0401057A external-priority patent/SE0401057D0/xx
Priority claimed from SE0500057A external-priority patent/SE0500057D0/sv
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20065319L publication Critical patent/NO20065319L/no

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • AIDS & HIV (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
NO20065319A 2004-04-23 2006-11-20 Piperidinderivater som modulatorer for kjemokinreseptor CCR5 NO20065319L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0401057A SE0401057D0 (sv) 2004-04-23 2004-04-23 Chemical Compounds
SE0500057A SE0500057D0 (sv) 2005-01-10 2005-01-10 Chemical compounds
PCT/SE2005/000574 WO2005101989A2 (fr) 2004-04-23 2005-04-20 Derives de piperidine utilises comme modulateurs du recepteur de la chimiokine ccr5

Publications (1)

Publication Number Publication Date
NO20065319L true NO20065319L (no) 2007-01-23

Family

ID=35197429

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065319A NO20065319L (no) 2004-04-23 2006-11-20 Piperidinderivater som modulatorer for kjemokinreseptor CCR5

Country Status (16)

Country Link
US (2) US7615555B2 (fr)
EP (1) EP1742934A2 (fr)
JP (1) JP2007533735A (fr)
KR (1) KR20070007345A (fr)
AR (1) AR048834A1 (fr)
AU (1) AU2005235169B2 (fr)
BR (1) BRPI0510126A (fr)
CA (1) CA2562417A1 (fr)
IL (1) IL178650A0 (fr)
MX (1) MXPA06012045A (fr)
NO (1) NO20065319L (fr)
RU (1) RU2368608C2 (fr)
SA (1) SA05260099B1 (fr)
TW (1) TW200610761A (fr)
UY (1) UY28870A1 (fr)
WO (1) WO2005101989A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602007007497D1 (de) * 2006-09-18 2010-08-12 Hoffmann La Roche Octahydropyrroloä3,4-cüpyrrolderivate und ihre verwendung als antivirale mittel
TW200831483A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
TW200831093A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
JP2010513272A (ja) * 2006-12-14 2010-04-30 メルク エンド カムパニー インコーポレーテッド アシルビピペリジニル化合物、そのような化合物を含む組成物、及び治療方法
WO2008101728A1 (fr) * 2007-02-23 2008-08-28 K.H.S. Pharma Holding Gmbh Procédé de production d'esters d'azoniaspironortropine et de composés nortropane-3-one
US7977358B2 (en) 2007-07-26 2011-07-12 Hoffmann-La Roche Inc. Pyrazol derivatives
DK2268646T3 (da) 2008-04-11 2013-11-18 Janssen Pharmaceutica Nv Thiazolopyridin-2-yloxy-phenyl og thiazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-a4-hydrolase
US8217060B2 (en) 2009-05-15 2012-07-10 Janssen Pharmaceutica, Nv Benzimidazole derivatives useful as TRP M8 receptor modulators
EP2456309B1 (fr) 2009-07-24 2015-12-23 GlaxoSmithKline LLC Dérivés de l'azabicyclo[3.2.1]octyle pour leur utilisation dans le traitement du VIH
CN102241664B (zh) * 2010-05-13 2014-11-12 上海医药工业研究院 芳烷二胺类衍生物及其作为抗抑郁症药物的应用
MX2012013465A (es) 2010-05-17 2013-12-02 Array Biopharma Inc Lactamas sustituidas con piperidinilo como moduladores de gpr119.
US20140309226A1 (en) * 2011-11-16 2014-10-16 Array Biopharma Inc. Piperidinyl-substituted cyclic ureas as gpr119 modulators
JP6303250B2 (ja) 2012-12-21 2018-04-04 石原産業株式会社 有害生物防除剤
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US10556899B2 (en) * 2018-02-09 2020-02-11 Sci Pharmtech, Inc. Method for preparing Maraviroc

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9100513A (es) 1990-08-06 1992-04-01 Smith Kline French Lab Compuestos
JP2002510327A (ja) * 1997-07-25 2002-04-02 メルク エンド カンパニー インコーポレーテッド 環状アミンケモカイン受容体活性調節剤
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
BR9814645A (pt) 1997-11-18 2001-07-31 Teijin Ltd Derivados de amina cìclica e seu uso como medicamentos
EP1052992A1 (fr) 1998-02-02 2000-11-22 Merck & Co., Inc. Amines cycliques utilisees en tant que modulateurs de l'activite du recepteur de chemokine
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
EP1013276A1 (fr) 1998-12-23 2000-06-28 Pfizer Inc. Aminoazacycloalcanes comme modulateurs de CCR5
US7217714B1 (en) * 1998-12-23 2007-05-15 Agouron Pharmaceuticals, Inc. CCR5 modulators
PE20001420A1 (es) * 1998-12-23 2000-12-18 Pfizer Moduladores de ccr5
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
GB0005642D0 (en) * 2000-03-10 2000-05-03 Astrazeneca Uk Ltd Chemical compounds
GB0011838D0 (en) * 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
DE60102233T2 (de) 2000-05-26 2005-01-27 Pfizer Inc. Triazolyltropanderivate als ccr5-modulatoren
SE0103818D0 (sv) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
EP1352672A3 (fr) * 2002-04-08 2004-01-07 Acrostak Corp. Ballonet PTCA et/ou PTA
US6855724B2 (en) * 2002-04-08 2005-02-15 Agouron Pharmaceuticals, Inc. Tropane derivatives useful in therapy
JP2006511554A (ja) * 2002-12-13 2006-04-06 スミスクライン ビーチャム コーポレーション Ｃｃｒ５アンタゴニストとしてのピペリジン誘導体
SE0203820D0 (sv) * 2002-12-20 2002-12-20 Astrazeneca Ab chemical compounds
AR042628A1 (es) 2002-12-20 2005-06-29 Astrazeneca Ab Derivados de piperidina como moduladores del receptor ccr5
SE0203828D0 (sv) 2002-12-20 2002-12-20 Astrazeneca Ab Chemical compounds
SE0401656D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
SE0401657D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
TW200831093A (en) 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
TW200831483A (en) 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound

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TW200610761A (en) 2006-04-01
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US7615555B2 (en) 2009-11-10
MXPA06012045A (es) 2007-01-25
WO2005101989A3 (fr) 2006-04-27
AU2005235169B2 (en) 2008-09-18
JP2007533735A (ja) 2007-11-22
IL178650A0 (en) 2007-02-11
RU2006138663A (ru) 2008-05-27
KR20070007345A (ko) 2007-01-15
RU2368608C2 (ru) 2009-09-27
US20100010007A1 (en) 2010-01-14
EP1742934A2 (fr) 2007-01-17
CA2562417A1 (fr) 2005-11-03
AU2005235169A1 (en) 2005-11-03
UY28870A1 (es) 2005-11-30
BRPI0510126A (pt) 2007-06-26
AR048834A1 (es) 2006-05-31

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