NO20064705L - Nye farmasoytiske preparater omfattende agonister av tyroidreseptoren - Google Patents
Nye farmasoytiske preparater omfattende agonister av tyroidreseptorenInfo
- Publication number
- NO20064705L NO20064705L NO20064705A NO20064705A NO20064705L NO 20064705 L NO20064705 L NO 20064705L NO 20064705 A NO20064705 A NO 20064705A NO 20064705 A NO20064705 A NO 20064705A NO 20064705 L NO20064705 L NO 20064705L
- Authority
- NO
- Norway
- Prior art keywords
- agonists
- thyroid receptor
- pharmaceutical preparations
- new pharmaceutical
- amide
- Prior art date
Links
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- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C07C233/27—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
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- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/24—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
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Abstract
Det tilveiebringes forbindelser med formel (I) eller en farmasøytisk akseptabel ester, amid, solvat eller salt derav, inkludert et salt av en slik ester eller amid og et solvat av en slik ester, amid eller salt. Det tilveiebringes videre beskrivelser av anvendelsen av slike forbindelser ved terapi eller profylakse av en tilstand mediert av en tyroidreseptor. Formel (I) der R1, R2, n, Y, Y1, R3, R4, W og R5 er som angitt i beskrivelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0406378.0A GB0406378D0 (en) | 2004-03-22 | 2004-03-22 | Novel pharmaceutical compositions |
PCT/EP2005/003030 WO2005092316A1 (en) | 2004-03-22 | 2005-03-22 | Novel pharmaceutical compositions comprising agonists of the thyroid receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064705L true NO20064705L (no) | 2006-12-19 |
Family
ID=32118142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064705A NO20064705L (no) | 2004-03-22 | 2006-10-18 | Nye farmasoytiske preparater omfattende agonister av tyroidreseptoren |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080004251A1 (no) |
EP (1) | EP1732532A1 (no) |
JP (1) | JP2007529566A (no) |
KR (1) | KR20060130728A (no) |
CN (1) | CN1933826A (no) |
AU (1) | AU2005226914A1 (no) |
BR (1) | BRPI0509074A (no) |
CA (1) | CA2560526A1 (no) |
GB (1) | GB0406378D0 (no) |
IL (1) | IL177665A0 (no) |
NO (1) | NO20064705L (no) |
WO (1) | WO2005092316A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4922615B2 (ja) | 2003-11-26 | 2012-04-25 | 武田薬品工業株式会社 | 受容体機能調節剤 |
FR2872159B1 (fr) * | 2004-06-28 | 2007-10-05 | Merck Sante Soc Par Actions Si | Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete |
GB0519294D0 (en) * | 2005-09-21 | 2005-11-02 | Karobio Ab | Compounds |
BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
TW201014822A (en) | 2008-07-09 | 2010-04-16 | Sanofi Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
CN102482312A (zh) | 2009-08-26 | 2012-05-30 | 赛诺菲 | 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途 |
WO2012030165A2 (ko) | 2010-08-31 | 2012-03-08 | 서울대학교산학협력단 | P P A R δ 활성물질의 태자재프로그래밍용도 |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120058A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120051A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP3445769A4 (en) | 2016-04-22 | 2020-02-12 | Metabasis Therapeutics, Inc. | THYROID HORMONE RECEPTOR AGONIST AND ITS USE |
TW202115029A (zh) * | 2019-07-31 | 2021-04-16 | 大陸商深圳微芯生物科技股份有限公司 | 雜環化合物及其用途 |
CN113134086B (zh) * | 2020-01-20 | 2024-05-24 | 深圳市长卿医学研究院 | 一种降血脂的药物组合物 |
WO2023177667A1 (en) * | 2022-03-16 | 2023-09-21 | Brii Biosciences, Inc. | Thyroid hormone receptor agonists |
Family Cites Families (13)
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GB1174051A (en) * | 1965-11-30 | 1969-12-10 | Beecham Group Ltd | Aminophenol Derivatives and Analgesic and Antipyretic Compositions |
BE689347A (no) * | 1965-12-09 | 1967-04-14 | Madan Ag | |
EP1083891B1 (en) * | 1998-06-02 | 2003-03-12 | Arthromics PLC | Compounds which interact with the thyroid hormone receptor for the treatment of fibrotic disease |
GB9816935D0 (en) * | 1998-08-05 | 1998-09-30 | Karobio Ab | Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders |
GB9927056D0 (en) * | 1999-11-17 | 2000-01-12 | Karobio Ab | Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders |
AU2001230929B2 (en) * | 2000-02-17 | 2004-09-23 | Bristol-Myers Squibb Co. | Aniline-derived ligands for the thyroid receptor |
EP1148054B1 (en) * | 2000-04-21 | 2005-11-23 | Pfizer Products Inc. | Thyroid receptor ligands |
US6395784B1 (en) * | 2000-06-07 | 2002-05-28 | Bristol-Myers Squibb Company | Benzamide ligands for the thyroid receptor |
GB0015205D0 (en) * | 2000-06-21 | 2000-08-09 | Karobio Ab | Bioisosteric thyroid receptor ligands and method |
AU2002364260A1 (en) * | 2001-12-31 | 2003-07-30 | Bayer Pharmaceuticals Corporation | Avb3 and avb5 integrin antagonists and methods of treating diseases or conditions associated with avb3 and avb5 integrins |
AU2003225305A1 (en) * | 2002-05-08 | 2003-11-11 | Bristol-Myers Squibb Company | Pyridine-based thyroid receptor ligands |
GB0215978D0 (en) * | 2002-07-10 | 2002-08-21 | Karobio Ab | Novel compounds |
GB0406380D0 (en) * | 2004-03-22 | 2004-04-21 | Karobio Ab | Novel pharmaceutical compositions |
-
2004
- 2004-03-22 GB GBGB0406378.0A patent/GB0406378D0/en not_active Ceased
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2005
- 2005-03-22 WO PCT/EP2005/003030 patent/WO2005092316A1/en active Application Filing
- 2005-03-22 AU AU2005226914A patent/AU2005226914A1/en not_active Abandoned
- 2005-03-22 BR BRPI0509074-1A patent/BRPI0509074A/pt not_active IP Right Cessation
- 2005-03-22 KR KR1020067021050A patent/KR20060130728A/ko not_active Application Discontinuation
- 2005-03-22 US US10/593,927 patent/US20080004251A1/en not_active Abandoned
- 2005-03-22 CN CNA2005800091283A patent/CN1933826A/zh active Pending
- 2005-03-22 CA CA002560526A patent/CA2560526A1/en not_active Abandoned
- 2005-03-22 EP EP05716286A patent/EP1732532A1/en not_active Withdrawn
- 2005-03-22 JP JP2007504341A patent/JP2007529566A/ja active Pending
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2006
- 2006-08-23 IL IL177665A patent/IL177665A0/en unknown
- 2006-10-18 NO NO20064705A patent/NO20064705L/no not_active Application Discontinuation
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CN1933826A (zh) | 2007-03-21 |
BRPI0509074A (pt) | 2007-08-21 |
GB0406378D0 (en) | 2004-04-21 |
JP2007529566A (ja) | 2007-10-25 |
KR20060130728A (ko) | 2006-12-19 |
CA2560526A1 (en) | 2005-10-06 |
WO2005092316A1 (en) | 2005-10-06 |
US20080004251A1 (en) | 2008-01-03 |
IL177665A0 (en) | 2008-03-20 |
EP1732532A1 (en) | 2006-12-20 |
AU2005226914A1 (en) | 2005-10-06 |
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