NO20063522L - Gastrointestinal proliferativ faktor og anvendelser derav - Google Patents

Gastrointestinal proliferativ faktor og anvendelser derav

Info

Publication number
NO20063522L
NO20063522L NO20063522A NO20063522A NO20063522L NO 20063522 L NO20063522 L NO 20063522L NO 20063522 A NO20063522 A NO 20063522A NO 20063522 A NO20063522 A NO 20063522A NO 20063522 L NO20063522 L NO 20063522L
Authority
NO
Norway
Prior art keywords
proliferative factor
gastrointestinal
gastrointestinal proliferative
gipf
factor
Prior art date
Application number
NO20063522A
Other languages
English (en)
Norwegian (no)
Inventor
Bryan J Boyle
Walter Funk
Makoto Kakitani
Takeshi Oshima
Eun Ju Park
Y Tom Tang
Mikio Yagi
Kazuma Tomizuka
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Publication of NO20063522L publication Critical patent/NO20063522L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Analytical Chemistry (AREA)
NO20063522A 2004-01-27 2006-08-02 Gastrointestinal proliferativ faktor og anvendelser derav NO20063522L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53960504P 2004-01-27 2004-01-27
US61924104P 2004-10-15 2004-10-15
PCT/US2005/002996 WO2005072419A2 (fr) 2004-01-27 2005-01-27 Facteur proliferatif gastro-intestinal et utilisations de celui-ci

Publications (1)

Publication Number Publication Date
NO20063522L true NO20063522L (no) 2006-10-25

Family

ID=34830487

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063522A NO20063522L (no) 2004-01-27 2006-08-02 Gastrointestinal proliferativ faktor og anvendelser derav

Country Status (14)

Country Link
US (4) US20050256036A1 (fr)
EP (1) EP1727560B1 (fr)
JP (1) JP2007526248A (fr)
KR (1) KR20070007289A (fr)
AU (1) AU2005208945A1 (fr)
BR (1) BRPI0507168A (fr)
CA (1) CA2554403A1 (fr)
IL (1) IL177060A0 (fr)
MX (1) MXPA06008495A (fr)
NO (1) NO20063522L (fr)
RU (2) RU2343158C2 (fr)
SG (1) SG149059A1 (fr)
TW (1) TW200536859A (fr)
WO (1) WO2005072419A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE466106T1 (de) * 2003-10-10 2010-05-15 Deutsches Krebsforsch Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen
US20190330295A1 (en) * 2005-05-04 2019-10-31 Zealand Pharma A/S Glucagon-like-peptide-2 (glp-2) analogues
EP1942926A4 (fr) * 2005-10-07 2010-06-16 Nuvelo Inc Scfa1, protéine du type facteur des cellules souches et utilisations de celle-ci
CA2669693C (fr) 2006-11-15 2018-06-12 Massachusetts Eye & Ear Infirmary Generation de cellules de l'oreille interne
WO2008088524A2 (fr) * 2006-12-28 2008-07-24 Nuvelo, Inc. Protéine r-spondine 1 à carence en domaines de thrombospondine utilisee en tant que facteur de prolifération épithéliale du tractus gastro-intestinal
AU2008270972B2 (en) 2007-07-02 2013-10-24 Oncomed Pharmaceuticals, Inc. Compositions and methods for treating and diagnosing cancer
US9464275B2 (en) 2008-08-21 2016-10-11 The Board Of Trustees Of The Leland Stanford Junior University Ex vivo culture, proliferation and expansion of intestinal epithelium
AU2009316264B2 (en) * 2008-11-24 2016-09-15 Massachusetts Eye & Ear Infirmary Pathways to generate hair cells
US9752124B2 (en) 2009-02-03 2017-09-05 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
EP3061808B1 (fr) 2009-02-03 2020-08-12 Koninklijke Nederlandse Akademie van Wetenschappen Milieu de culture de cellules souches épithéliales et organoïdes comprenant lesdites cellules souches
EP2412800A1 (fr) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Organoïde du foie, ses utilisations et son procédé de culture pour l'obtenir
IT1396935B1 (it) 2009-11-26 2012-12-20 Solartium Entpr Ltd Uso di una combinazione per il trattamento delle mucositi indotte da radiazioni o da chemioterapici
RU2532323C2 (ru) * 2011-06-20 2014-11-10 Мапикс Эс.Эй.Ар.Эл. Лекарственное средство для лечения патологического синдрома и способ лечения функциональных нарушений кишечника
GB201106395D0 (en) * 2011-04-14 2011-06-01 Hubrecht Inst Compounds
CN106167526A (zh) 2011-07-15 2016-11-30 昂考梅德药品有限公司 Rspo结合剂和其应用
AU2013289990B2 (en) 2012-07-13 2018-06-14 Oncomed Pharmaceuticals, Inc. RSPO3 binding agents and uses thereof
JP2015527398A (ja) 2012-09-07 2015-09-17 マサチューセッツ アイ アンド イヤー インファーマリー 聴覚喪失治療
US10047134B2 (en) * 2013-01-10 2018-08-14 Biocon Limited Process for expression of recombinant proteins in Pichia pastoris using a fed batch model
WO2016022776A2 (fr) 2014-08-06 2016-02-11 Massachusetts Eye And Ear Infirmary Augmentation de la durée de vie d'atoh1 pour diriger la différenciation des cellules ciliées neurosensorielles
CA2961374A1 (fr) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Traitement de maladies fibrotiques
JP6920203B2 (ja) * 2015-01-30 2021-08-18 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｃａｒｏｌｉｎａ Ａｔ Ｃｈａｐｅｌ Ｈｉｌｌ 消化管上皮組織構築物を生成する方法
US11185536B2 (en) 2015-12-04 2021-11-30 Massachusetts Eye And Ear Infirmary Treatment of hearing loss by inhibition of casein kinase 1
EP3943090A1 (fr) 2016-01-29 2022-01-26 Massachusetts Eye & Ear Infirmary Expansion et différenciation des cellules de support de l'oreille interne, et méthodes d'utilisation de ces dernières
US11180735B2 (en) 2016-10-28 2021-11-23 The Board Of Trustees Of The Leland Stanford Junior University Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof
WO2021247497A1 (fr) * 2020-06-03 2021-12-09 Children's Hospital Medical Center Compositions et procédés comprenant des r-spondines pour le traitement de tumeurs
JP2024519126A (ja) 2021-05-21 2024-05-08 エンブレーション リミテッド 組織のマイクロ波治療
WO2023097236A1 (fr) * 2021-11-24 2023-06-01 The Rockefeller University Compositions et procédés pour générer des souris knock-in d'immunoglobuline

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6824973B2 (en) * 2000-02-03 2004-11-30 Kirin Beer Kabushiki Kaisha Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide
AU5904101A (en) 2000-04-05 2001-10-23 Hyseq Inc Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
US7411052B2 (en) * 2001-03-05 2008-08-12 Nuvelo, Inc. Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
US20030032034A1 (en) * 2001-03-05 2003-02-13 Tang Y. Tom Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
JP4208715B2 (ja) * 2001-08-30 2009-01-14 ヌヴェロ， インコーポレイテッド 幹細胞増殖因子様ポリペプチドおよびポリヌクレオチドに関する方法および材料
EP1434796A2 (fr) 2001-10-03 2004-07-07 Incyte Genomics, Inc. Proteines secretees
WO2003054152A2 (fr) * 2001-12-10 2003-07-03 Nuvelo, Inc. Nouveaux acides nucleiques et polypeptides
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2005110009A2 (fr) 2003-07-22 2005-11-24 Immunex Corporation Compositions et methodes relatives aux tsp-30a, b, c et d
WO2005032574A1 (fr) * 2003-10-03 2005-04-14 The Board Of Trustees Of The Leland Stanford Junior University Modulation de la proliferation de l'epithelium gastrointestinal par voie de signalisation wnt
ATE466106T1 (de) * 2003-10-10 2010-05-15 Deutsches Krebsforsch Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen

Also Published As

Publication number Publication date
TW200536859A (en) 2005-11-16
EP1727560B1 (fr) 2012-09-12
US7951381B2 (en) 2011-05-31
MXPA06008495A (es) 2007-05-23
WO2005072419A3 (fr) 2007-06-28
BRPI0507168A (pt) 2007-06-26
AU2005208945A1 (en) 2005-08-11
EP1727560A2 (fr) 2006-12-06
WO2005072419A2 (fr) 2005-08-11
US20050256036A1 (en) 2005-11-17
KR20070007289A (ko) 2007-01-15
RU2008136324A (ru) 2010-03-20
SG149059A1 (en) 2009-01-29
RU2343158C2 (ru) 2009-01-10
RU2006130791A (ru) 2008-03-27
US20100137210A1 (en) 2010-06-03
EP1727560A4 (fr) 2009-09-09
IL177060A0 (en) 2008-03-20
JP2007526248A (ja) 2007-09-13
US20080300183A1 (en) 2008-12-04
US20050256044A1 (en) 2005-11-17
CA2554403A1 (fr) 2005-08-11

Similar Documents

Publication Publication Date Title
NO20063522L (no) Gastrointestinal proliferativ faktor og anvendelser derav
IL219915A0 (en) Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
NO20070049L (no) Pyrrolotriazinderivater anvendelig for behandling av hyperproliferative forstyrrelser og sykdommer assosiert med angiogenese
NO20074823L (no) Rasagilin-formuleringer med forbedret innholdsensartethet
MY147677A (en) Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases
CL2007002578A1 (es) Compuestos derivados de n-(1-ftalazin-1-il-piperidin-4-il)-amidas; composicion farmaceutica; y uso para el tratamiento y prevencion de trastornos de la fertilidad, osteoporosis y cancer.
WO2008002621A3 (fr) Effecteurs allostériques positifs du récepteur m1 à base de quinolone à substitution benzyle
EA201290322A1 (ru) Лечение желудочно-кишечных расстройств
NO20075074L (no) Kinazolinon T-type-kalsiumkanalantagonister
CL2008002954A1 (es) Compuestos derivados de 1,2,3,3a,3b,4,5,7,10,10a,10b,11,12,12a-tetradecahidrociclopenta-(5,6)nafto-(1,2-f)indazol heterociclo o carbociclo sustituido; procedimiento de preparacion; composicion farmaceutica; y su uso en el tratamiento de asma, epoc, rinits alergica.
MY149492A (en) Immunoglobulins directed against nogo
MX2010006388A (es) Bis-piridilpiridonas como antagonistas del receptor 1 de la hormona concentradora de melanina.
EA200970302A1 (ru) Тиофенпиразолопиримидиновые соединения
TW200745081A (en) Compounds
LU92202I9 (fr)
GB0611907D0 (en) Compounds
WO2006065600A3 (fr) Derives de n-biaryl et de n-arylheteroaryl piperazine servant de modulateurs du recepteur 5ht2c utilises pour le traitement de troubles associes a celui-ci
WO2008013983A3 (fr) Composés stabilisant les opsines et procédés d'utilisation
WO2006028492A3 (fr) Hc1q/tnf7 et ses utilisations
GB0519760D0 (en) Novel compounds
TW200716561A (en) P38 inhibitors and methods of use thereof
WO2008034909A3 (fr) Traitement de seconde intention du cancer métastatique hormono-résistant de la prostate à l'aide de satraplatine
WO2006128120A3 (fr) Nouveaux composes de lapachone et methodes d'utilisation
ZA200705349B (en) Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
BRPI0419229A (pt) derivados de tiofenopirimidinona substituìdos como inibidores de 17beta-hidroxiesteróide-desidrogenase, uso e composição farmacêutica

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application