NO20063461L - Nye polysubstituert 1,1-pyridyloksycyklopropanaminforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem - Google Patents

Nye polysubstituert 1,1-pyridyloksycyklopropanaminforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Info

Publication number
NO20063461L
NO20063461L NO20063461A NO20063461A NO20063461L NO 20063461 L NO20063461 L NO 20063461L NO 20063461 A NO20063461 A NO 20063461A NO 20063461 A NO20063461 A NO 20063461A NO 20063461 L NO20063461 L NO 20063461L
Authority
NO
Norway
Prior art keywords
pyridyloxycyclopropanamine
compounds
preparation
methods
pharmaceutical compositions
Prior art date
Application number
NO20063461A
Other languages
English (en)
Inventor
Brian Lockhart
Pierre Lestage
Solo Goldstein
Claude Guillonneau
Yves Charton
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20063461L publication Critical patent/NO20063461L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

n representerer et heltall fra 1 til og med 6,. Ri og Rrepresenterer et hydrogenatom, en (C-C)alkylgruppe eller en aryl-(C-C)alkylgruppe, Rog Rrepresenterer et hydrogenatom eller en (Ci-GOalkylgmppe,. Rog Rrepresenterer et hydrogenatom, eller et (C-C)alkyl, halogen, hydroksy, (C-C)alkoksy, cyano, nitro, (C-C)acyl, (Cl-C)alkoksykarbonyl, (C-C)trihaloalkyl, (C-C)trihaloalkoksy eller eventuelt substituert aminogruppe. Medikamenter.
NO20063461A 2005-07-28 2006-07-27 Nye polysubstituert 1,1-pyridyloksycyklopropanaminforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem NO20063461L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0508033A FR2889187B1 (fr) 2005-07-28 2005-07-28 Nouveaux composes 1,1-pyridinyloxycyclopropanamines polysusbstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
NO20063461L true NO20063461L (no) 2007-01-29

Family

ID=35841768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063461A NO20063461L (no) 2005-07-28 2006-07-27 Nye polysubstituert 1,1-pyridyloksycyklopropanaminforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Country Status (27)

Country Link
US (1) US7348344B2 (no)
EP (1) EP1748043B1 (no)
JP (1) JP2007077135A (no)
KR (1) KR100824830B1 (no)
CN (1) CN100519531C (no)
AR (1) AR054875A1 (no)
AT (1) ATE405550T1 (no)
AU (1) AU2006203241A1 (no)
BR (1) BRPI0603064A (no)
CA (1) CA2552827A1 (no)
DE (1) DE602006002328D1 (no)
DK (1) DK1748043T3 (no)
EA (1) EA011126B1 (no)
ES (1) ES2313589T3 (no)
FR (1) FR2889187B1 (no)
GE (1) GEP20084548B (no)
HR (1) HRP20080536T5 (no)
MA (1) MA28426B1 (no)
MX (1) MXPA06008415A (no)
NO (1) NO20063461L (no)
NZ (1) NZ548747A (no)
PL (1) PL1748043T3 (no)
PT (1) PT1748043E (no)
SG (1) SG129411A1 (no)
SI (1) SI1748043T1 (no)
WO (1) WO2007012762A1 (no)
ZA (1) ZA200606277B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2896800B1 (fr) * 2006-01-30 2008-04-11 Servier Lab Nouveaux composes pyridinylaminoalkylene-et pyridinyloxyalkylene-cyclopropanamines polysubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
HUE033352T2 (en) * 2009-11-18 2017-11-28 Suven Life Sciences Ltd Bicyclic compounds as alpha4-beta2 nicotinic acetylcholine receptor ligands

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2095350C1 (ru) * 1993-10-13 1997-11-10 Центр по химии лекарственных средств (ЦХЛС-ВНИХФИ) 3-(n,n-диметилкарбамоилокси)-2-этил-6-метилпиридина сукцинат, обладающий антигипоксической активностью
TW544448B (en) * 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
FR2810664B1 (fr) * 2000-06-27 2004-12-24 Adir Nouveaux composes cyclopropaniques 1,1 et 1,2-dissubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
WO2007012762A1 (fr) 2007-02-01
MXPA06008415A (es) 2007-01-29
DE602006002328D1 (de) 2008-10-02
HRP20080536T3 (en) 2009-02-28
ZA200606277B (en) 2007-04-25
BRPI0603064A (pt) 2007-08-14
ATE405550T1 (de) 2008-09-15
EP1748043B1 (fr) 2008-08-20
PT1748043E (pt) 2008-10-07
MA28426B1 (fr) 2007-02-01
SG129411A1 (en) 2007-02-26
US7348344B2 (en) 2008-03-25
DK1748043T3 (da) 2008-12-08
GEP20084548B (en) 2008-11-25
AR054875A1 (es) 2007-07-25
EA011126B1 (ru) 2008-12-30
CA2552827A1 (fr) 2007-01-28
KR100824830B1 (ko) 2008-04-23
FR2889187A1 (fr) 2007-02-02
EP1748043A1 (fr) 2007-01-31
PL1748043T3 (pl) 2008-12-31
JP2007077135A (ja) 2007-03-29
CN100519531C (zh) 2009-07-29
HRP20080536T5 (en) 2009-03-31
CN1903843A (zh) 2007-01-31
EA200601248A1 (ru) 2007-04-27
ES2313589T3 (es) 2009-03-01
NZ548747A (en) 2007-06-29
KR20070015011A (ko) 2007-02-01
US20070027191A1 (en) 2007-02-01
SI1748043T1 (sl) 2008-12-31
AU2006203241A1 (en) 2007-02-15
FR2889187B1 (fr) 2007-09-07

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