NO20055777L - Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer - Google Patents

Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer

Info

Publication number
NO20055777L
NO20055777L NO20055777A NO20055777A NO20055777L NO 20055777 L NO20055777 L NO 20055777L NO 20055777 A NO20055777 A NO 20055777A NO 20055777 A NO20055777 A NO 20055777A NO 20055777 L NO20055777 L NO 20055777L
Authority
NO
Norway
Prior art keywords
desaturase
fatty acids
oleic
levels
altering
Prior art date
Application number
NO20055777A
Other languages
English (en)
Other versions
NO20055777D0 (no
Inventor
Narendra S Yadav
Hongxiang Zhang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NO20055777D0 publication Critical patent/NO20055777D0/no
Publication of NO20055777L publication Critical patent/NO20055777L/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Den foreliggende oppfinnelsen er relatert til en A12-fettsyredesaturase i stand til å katalysere omdannelsen av oljesyre til linolsyre (LA; 18:2). Nukleinsyresekvenser som koder for desaturasen, nukleinsyresekvenser som hybridiserer til disse, DNA-konstruksjoner som omfatter desaturasegenet, og rekombinante vertsmikroorganismer som uttrykker økte nivåer av desaturasen er beskrevet. Fremgangsmåter for å øke produksjon av spesifikke (d-3 og/eller (d-6 fettsyrer er beskrevet ved overekspresjon av A12-fettsyre- desaturasen eller ved å ødelegge det naturlige genet.
NO20055777A 2003-05-07 2005-12-06 Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer NO20055777L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46867703P 2003-05-07 2003-05-07
US48420903P 2003-06-30 2003-06-30
PCT/US2004/014542 WO2004104167A2 (en) 2003-05-07 2004-05-07 A δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts

Publications (2)

Publication Number Publication Date
NO20055777D0 NO20055777D0 (no) 2005-12-06
NO20055777L true NO20055777L (no) 2006-02-07

Family

ID=33479252

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055777A NO20055777L (no) 2003-05-07 2005-12-06 Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer

Country Status (7)

Country Link
US (3) US7214491B2 (no)
EP (1) EP1620561A4 (no)
AU (1) AU2004242095A1 (no)
BR (1) BRPI0410681A (no)
CA (1) CA2523786A1 (no)
NO (1) NO20055777L (no)
WO (1) WO2004104167A2 (no)

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US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
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US8846374B2 (en) * 2006-12-12 2014-09-30 E I Du Pont De Nemours And Company Carotenoid production in a recombinant oleaginous yeast
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US7943365B2 (en) 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
WO2009046248A1 (en) * 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Peroxisome biogenesis factor protein (pex) disruptions for altering the content of polyunsaturated fatty acids and the total lipid content in oleaginous eukaryotic organisms
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US7892792B2 (en) 2008-06-27 2011-02-22 Indian Institute Of Science Cells expressing Pichia cytochrome C
JP5645840B2 (ja) 2008-12-02 2014-12-24 株式会社Wave Life Sciences Japan リン原子修飾核酸の合成方法
WO2010080388A1 (en) 2008-12-18 2010-07-15 E. I. Du Pont De Nemours And Company Reducing byproduction of malonates in a fermentation process
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US8765404B2 (en) 2010-03-02 2014-07-01 Massachusetts Institute Of Technology Microbial engineering for the production of fatty acids and fatty acid derivatives
EP2561050A1 (en) * 2010-04-22 2013-02-27 E.I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
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WO2014012081A2 (en) 2012-07-13 2014-01-16 Ontorii, Inc. Chiral control
PL2872485T3 (pl) 2012-07-13 2021-05-31 Wave Life Sciences Ltd. Asymetryczna grupa pomocnicza
AU2013287630B2 (en) 2012-07-13 2017-05-25 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant
CN102787128A (zh) * 2012-08-28 2012-11-21 江南大学 一种用于多不饱和脂肪酸生物合成的脱饱和酶Δ9 Des
JP2016502851A (ja) 2012-12-21 2016-02-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company 微生物細胞中における脂質生成を改変するためのsou2ソルビトール利用タンパク質をコードするポリヌクレオチドの下方制御
AU2014229307B2 (en) 2013-03-13 2017-08-31 Dsm Nutritional Products Ag Engineering microorganisms
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EP3095460A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
WO2015108047A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
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Also Published As

Publication number Publication date
WO2004104167A3 (en) 2005-04-28
EP1620561A4 (en) 2006-08-23
US20060263866A1 (en) 2006-11-23
BRPI0410681A (pt) 2006-06-20
EP1620561A2 (en) 2006-02-01
US20050043527A1 (en) 2005-02-24
US20060263867A1 (en) 2006-11-23
AU2004242095A1 (en) 2004-12-02
WO2004104167A2 (en) 2004-12-02
CA2523786A1 (en) 2004-12-02
US7749703B2 (en) 2010-07-06
US7214491B2 (en) 2007-05-08
NO20055777D0 (no) 2005-12-06

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