NO20054478L - Framgangsmate for framstilling av syklosporin A-analog - Google Patents
Framgangsmate for framstilling av syklosporin A-analogInfo
- Publication number
- NO20054478L NO20054478L NO20054478A NO20054478A NO20054478L NO 20054478 L NO20054478 L NO 20054478L NO 20054478 A NO20054478 A NO 20054478A NO 20054478 A NO20054478 A NO 20054478A NO 20054478 L NO20054478 L NO 20054478L
- Authority
- NO
- Norway
- Prior art keywords
- cyclosporin
- analog
- procedure
- preparation
- formula
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
- -1 cyclosporin A aldehyde Chemical class 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03007921 | 2003-04-08 | ||
PCT/EP2004/003504 WO2004089960A2 (en) | 2003-04-08 | 2004-04-02 | Process for preparation of cyclosporin “a” analogues having a terminal diene group |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20054478D0 NO20054478D0 (no) | 2005-09-28 |
NO20054478L true NO20054478L (no) | 2005-10-17 |
Family
ID=33155122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054478A NO20054478L (no) | 2003-04-08 | 2005-09-28 | Framgangsmate for framstilling av syklosporin A-analog |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040220091A1 (ja) |
EP (1) | EP1613646A2 (ja) |
JP (1) | JP2006525961A (ja) |
KR (1) | KR20050119200A (ja) |
CN (1) | CN1798759A (ja) |
AU (1) | AU2004228159A1 (ja) |
BR (1) | BRPI0409734A (ja) |
CA (1) | CA2521116A1 (ja) |
CO (1) | CO5680450A2 (ja) |
EC (1) | ECSP056091A (ja) |
MA (1) | MA27831A1 (ja) |
MX (1) | MXPA05010794A (ja) |
NO (1) | NO20054478L (ja) |
RU (1) | RU2005130508A (ja) |
TN (1) | TNSN05255A1 (ja) |
TW (1) | TW200505946A (ja) |
WO (1) | WO2004089960A2 (ja) |
ZA (1) | ZA200507980B (ja) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6859799B1 (en) | 1998-11-30 | 2005-02-22 | Gemstar Development Corporation | Search engine for video and graphics |
US7103906B1 (en) | 2000-09-29 | 2006-09-05 | International Business Machines Corporation | User controlled multi-device media-on-demand system |
MX336193B (es) | 2000-10-11 | 2016-01-11 | Rovi Guides Inc | Sistemas y metodos para proporcionar almacenamiento de datos en servidores, mediante un sistema de entrega de medios a peticion. |
US7493646B2 (en) | 2003-01-30 | 2009-02-17 | United Video Properties, Inc. | Interactive television systems with digital video recording and adjustable reminders |
EP1603512A2 (en) * | 2003-03-17 | 2005-12-14 | Albany Molecular Research, Inc. | Novel cyclosporins |
US7799756B2 (en) * | 2004-07-29 | 2010-09-21 | Albany Molecular Research, Inc. | Processes for stereoselective synthesis of trans ISATX247 |
US8086575B2 (en) | 2004-09-23 | 2011-12-27 | Rovi Solutions Corporation | Methods and apparatus for integrating disparate media formats in a networked media system |
JP2008514701A (ja) * | 2004-09-29 | 2008-05-08 | エーエムアール テクノロジー インコーポレイテッド | シクロスポリンアルキン類似体およびそれらの薬学的使用 |
US7511013B2 (en) * | 2004-09-29 | 2009-03-31 | Amr Technology, Inc. | Cyclosporin analogues and their pharmaceutical uses |
JP2008515886A (ja) * | 2004-10-06 | 2008-05-15 | エーエムアール テクノロジー インコーポレイテッド | シクロスポリンアルキンおよびそれらの医用薬剤としての有用性 |
KR100780718B1 (ko) | 2004-12-28 | 2007-12-26 | 엘지.필립스 엘시디 주식회사 | 도포액 공급장치를 구비한 슬릿코터 |
US9681105B2 (en) | 2005-12-29 | 2017-06-13 | Rovi Guides, Inc. | Interactive media guidance system having multiple devices |
US8607287B2 (en) | 2005-12-29 | 2013-12-10 | United Video Properties, Inc. | Interactive media guidance system having multiple devices |
US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
US20090019492A1 (en) | 2007-07-11 | 2009-01-15 | United Video Properties, Inc. | Systems and methods for mirroring and transcoding media content |
EP2197461B1 (en) | 2007-10-08 | 2018-02-21 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors |
US8601526B2 (en) | 2008-06-13 | 2013-12-03 | United Video Properties, Inc. | Systems and methods for displaying media content and media guidance information |
FR2934997B1 (fr) * | 2008-08-14 | 2010-09-24 | Minakem | Derives cyclopropyl-et cyclobutyl-dioxazaborocanes ou dioxazaborecanes |
ES2537385T3 (es) | 2009-06-09 | 2015-06-08 | Aurinia Pharmaceuticals Inc. | Sistemas de suministro tópico para uso oftálmico |
US9014546B2 (en) | 2009-09-23 | 2015-04-21 | Rovi Guides, Inc. | Systems and methods for automatically detecting users within detection regions of media devices |
US9200038B2 (en) | 2010-12-15 | 2015-12-01 | Ciclofilin Pharmaceuticals Corp. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
US8805418B2 (en) | 2011-12-23 | 2014-08-12 | United Video Properties, Inc. | Methods and systems for performing actions based on location-based rules |
AR090964A1 (es) | 2012-05-09 | 2014-12-17 | Novartis Ag | Proceso para la elaboracion de undecapeptidos ciclicos |
US9674563B2 (en) | 2013-11-04 | 2017-06-06 | Rovi Guides, Inc. | Systems and methods for recommending content |
US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
EP4201952A1 (en) | 2021-12-21 | 2023-06-28 | Curia Spain, S.A.U. | Process for the controlled synthesis of voclosporin |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE95193T1 (de) * | 1987-06-17 | 1993-10-15 | Sandoz Ag | Cyclosporine und deren benutzung als arzneimittel. |
WO1998048791A1 (en) * | 1997-04-30 | 1998-11-05 | The Regents Of The University Of California | Synthesis of discodermolide and analogs |
ATE314388T1 (de) * | 1997-10-08 | 2006-01-15 | Isotechnika Inc | Deuterierte und undeuterierte cyclosporin-analoga und ihre verwendung als immunmodulierende agentien |
DE10143979A1 (de) * | 2001-09-07 | 2003-03-27 | Clariant Gmbh | Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren |
AR036853A1 (es) * | 2001-10-19 | 2004-10-06 | Isotechnika Inc | Mezclas de analogos de ciclosporina y su uso como agentes inmunomoduladores. |
SI1436321T1 (sl) * | 2001-10-19 | 2006-12-31 | Isotechnika Inc | Sinteza analogov ciklosporina |
-
2004
- 2004-03-31 TW TW093108938A patent/TW200505946A/zh unknown
- 2004-04-02 MX MXPA05010794A patent/MXPA05010794A/es unknown
- 2004-04-02 CN CNA2004800154235A patent/CN1798759A/zh active Pending
- 2004-04-02 AU AU2004228159A patent/AU2004228159A1/en not_active Abandoned
- 2004-04-02 RU RU2005130508/04A patent/RU2005130508A/ru not_active Application Discontinuation
- 2004-04-02 JP JP2006504961A patent/JP2006525961A/ja not_active Withdrawn
- 2004-04-02 EP EP04725333A patent/EP1613646A2/en not_active Withdrawn
- 2004-04-02 KR KR1020057019162A patent/KR20050119200A/ko not_active Application Discontinuation
- 2004-04-02 WO PCT/EP2004/003504 patent/WO2004089960A2/en not_active Application Discontinuation
- 2004-04-02 ZA ZA200507980A patent/ZA200507980B/en unknown
- 2004-04-02 CA CA002521116A patent/CA2521116A1/en not_active Abandoned
- 2004-04-02 BR BRPI0409734-3A patent/BRPI0409734A/pt not_active Application Discontinuation
- 2004-04-05 US US10/817,991 patent/US20040220091A1/en not_active Abandoned
-
2005
- 2005-09-28 NO NO20054478A patent/NO20054478L/no not_active Application Discontinuation
- 2005-10-06 CO CO05101444A patent/CO5680450A2/es not_active Application Discontinuation
- 2005-10-07 MA MA28540A patent/MA27831A1/fr unknown
- 2005-10-07 EC EC2005006091A patent/ECSP056091A/es unknown
- 2005-10-07 TN TNP2005000255A patent/TNSN05255A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO20054478D0 (no) | 2005-09-28 |
CO5680450A2 (es) | 2006-09-29 |
US20040220091A1 (en) | 2004-11-04 |
TNSN05255A1 (en) | 2007-07-10 |
MA27831A1 (fr) | 2006-04-03 |
JP2006525961A (ja) | 2006-11-16 |
BRPI0409734A (pt) | 2006-05-09 |
CN1798759A (zh) | 2006-07-05 |
ZA200507980B (en) | 2006-11-29 |
TW200505946A (en) | 2005-02-16 |
ECSP056091A (es) | 2006-03-01 |
KR20050119200A (ko) | 2005-12-20 |
EP1613646A2 (en) | 2006-01-11 |
RU2005130508A (ru) | 2006-06-27 |
CA2521116A1 (en) | 2004-10-21 |
MXPA05010794A (es) | 2005-12-14 |
WO2004089960A2 (en) | 2004-10-21 |
WO2004089960A3 (en) | 2005-01-06 |
AU2004228159A1 (en) | 2004-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |