TW200505946A - Process for preparation of cyclosporin a analog - Google Patents

Process for preparation of cyclosporin a analog

Info

Publication number
TW200505946A
TW200505946A TW093108938A TW93108938A TW200505946A TW 200505946 A TW200505946 A TW 200505946A TW 093108938 A TW093108938 A TW 093108938A TW 93108938 A TW93108938 A TW 93108938A TW 200505946 A TW200505946 A TW 200505946A
Authority
TW
Taiwan
Prior art keywords
cyclosporin
analog
preparation
formula
allylmetal
Prior art date
Application number
TW093108938A
Other languages
English (en)
Inventor
Jean-Michel Adam
Mark Abel
Seetharaman Jayaraman
Original Assignee
Hoffmann La Roche
Isotechnika Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Isotechnika Inc filed Critical Hoffmann La Roche
Publication of TW200505946A publication Critical patent/TW200505946A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW093108938A 2003-04-08 2004-03-31 Process for preparation of cyclosporin a analog TW200505946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03007921 2003-04-08

Publications (1)

Publication Number Publication Date
TW200505946A true TW200505946A (en) 2005-02-16

Family

ID=33155122

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093108938A TW200505946A (en) 2003-04-08 2004-03-31 Process for preparation of cyclosporin a analog

Country Status (18)

Country Link
US (1) US20040220091A1 (zh)
EP (1) EP1613646A2 (zh)
JP (1) JP2006525961A (zh)
KR (1) KR20050119200A (zh)
CN (1) CN1798759A (zh)
AU (1) AU2004228159A1 (zh)
BR (1) BRPI0409734A (zh)
CA (1) CA2521116A1 (zh)
CO (1) CO5680450A2 (zh)
EC (1) ECSP056091A (zh)
MA (1) MA27831A1 (zh)
MX (1) MXPA05010794A (zh)
NO (1) NO20054478L (zh)
RU (1) RU2005130508A (zh)
TN (1) TNSN05255A1 (zh)
TW (1) TW200505946A (zh)
WO (1) WO2004089960A2 (zh)
ZA (1) ZA200507980B (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6859799B1 (en) 1998-11-30 2005-02-22 Gemstar Development Corporation Search engine for video and graphics
US7103906B1 (en) 2000-09-29 2006-09-05 International Business Machines Corporation User controlled multi-device media-on-demand system
US7650621B2 (en) 2000-10-11 2010-01-19 United Video Properties, Inc. Systems and methods for providing storage of data on servers in an on-demand media delivery system
US7493646B2 (en) 2003-01-30 2009-02-17 United Video Properties, Inc. Interactive television systems with digital video recording and adjustable reminders
AU2004222306A1 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
CA2575280C (en) * 2004-07-29 2012-08-14 Amr Technology, Inc. Novel processes for stereoselective synthesis of trans isatx 247
US8086575B2 (en) 2004-09-23 2011-12-27 Rovi Solutions Corporation Methods and apparatus for integrating disparate media formats in a networked media system
JP2008514701A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
US7511013B2 (en) * 2004-09-29 2009-03-31 Amr Technology, Inc. Cyclosporin analogues and their pharmaceutical uses
JP2008515886A (ja) * 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
KR100780718B1 (ko) 2004-12-28 2007-12-26 엘지.필립스 엘시디 주식회사 도포액 공급장치를 구비한 슬릿코터
US8607287B2 (en) 2005-12-29 2013-12-10 United Video Properties, Inc. Interactive media guidance system having multiple devices
US9681105B2 (en) 2005-12-29 2017-06-13 Rovi Guides, Inc. Interactive media guidance system having multiple devices
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US20090019492A1 (en) 2007-07-11 2009-01-15 United Video Properties, Inc. Systems and methods for mirroring and transcoding media content
ES2667945T3 (es) 2007-10-08 2018-05-16 Aurinia Pharmaceuticals Inc. Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR
US8601526B2 (en) 2008-06-13 2013-12-03 United Video Properties, Inc. Systems and methods for displaying media content and media guidance information
FR2934997B1 (fr) * 2008-08-14 2010-09-24 Minakem Derives cyclopropyl-et cyclobutyl-dioxazaborocanes ou dioxazaborecanes
AU2010259184B2 (en) 2009-06-09 2015-08-13 Aurinia Pharmaceuticals Inc. Topical drug delivery systems for ophthalmic use
US9014546B2 (en) 2009-09-23 2015-04-21 Rovi Guides, Inc. Systems and methods for automatically detecting users within detection regions of media devices
JP6144627B2 (ja) 2010-12-15 2017-06-07 コントラヴィア ファーマシューティカルズ、インク． アミノ酸１および３で修飾されたシクロスポリン類似体分子
US8805418B2 (en) 2011-12-23 2014-08-12 United Video Properties, Inc. Methods and systems for performing actions based on location-based rules
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos
US9674563B2 (en) 2013-11-04 2017-06-06 Rovi Guides, Inc. Systems and methods for recommending content
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
EP4201952A1 (en) 2021-12-21 2023-06-28 Curia Spain, S.A.U. Process for the controlled synthesis of voclosporin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
WO1998048791A1 (en) * 1997-04-30 1998-11-05 The Regents Of The University Of California Synthesis of discodermolide and analogs
ATE423130T1 (de) * 1997-10-08 2009-03-15 Isotechnika Inc Deuterierte cyclosporin-analoga und ihre verwendung als immunmodulierende agenzien
DE10143979A1 (de) * 2001-09-07 2003-03-27 Clariant Gmbh Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren
DK1436321T3 (da) * 2001-10-19 2006-11-13 Isotechnika Inc Syntese af cyclosporinanaloger
ES2310604T3 (es) * 2001-10-19 2009-01-16 Isotechnika, Inc. Mezclas de analogos de ciclosporinas y su uso como agentes inmunomoduladores.

Also Published As

Publication number Publication date
CO5680450A2 (es) 2006-09-29
KR20050119200A (ko) 2005-12-20
BRPI0409734A (pt) 2006-05-09
ECSP056091A (es) 2006-03-01
NO20054478L (no) 2005-10-17
AU2004228159A1 (en) 2004-10-21
JP2006525961A (ja) 2006-11-16
US20040220091A1 (en) 2004-11-04
MA27831A1 (fr) 2006-04-03
CN1798759A (zh) 2006-07-05
TNSN05255A1 (en) 2007-07-10
RU2005130508A (ru) 2006-06-27
WO2004089960A3 (en) 2005-01-06
CA2521116A1 (en) 2004-10-21
ZA200507980B (en) 2006-11-29
NO20054478D0 (no) 2005-09-28
WO2004089960A2 (en) 2004-10-21
EP1613646A2 (en) 2006-01-11
MXPA05010794A (es) 2005-12-14

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