NO20050764L - Forbindelser - Google Patents

Forbindelser

Info

Publication number
NO20050764L
NO20050764L NO20050764A NO20050764A NO20050764L NO 20050764 L NO20050764 L NO 20050764L NO 20050764 A NO20050764 A NO 20050764A NO 20050764 A NO20050764 A NO 20050764A NO 20050764 L NO20050764 L NO 20050764L
Authority
NO
Norway
Prior art keywords
compounds
formula
4alkynyl
4alkenyl
tace
Prior art date
Application number
NO20050764A
Other languages
English (en)
Inventor
Howard Tucker
Jeremy Nicholas Burrows
Ian Patel
Simon James Brown
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20050764L publication Critical patent/NO20050764L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En forbindelse med formel (1): (D)n, R* R3 formel (1) R1 R8 der B er eventuelt substituet C2-4alkenyl eller Ci^ialkynyl; som er nyttig ved inhibisjon av en eller flere metalloproteinaser og i særdeleshet TACE.
NO20050764A 2002-07-13 2005-02-11 Forbindelser NO20050764L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216382.2A GB0216382D0 (en) 2002-07-13 2002-07-13 Compounds
PCT/GB2003/002985 WO2004006927A2 (en) 2002-07-13 2003-07-09 Sulphonylpiperidine derivatives containing an alkenyl or alkynly moiety for use as matrix metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
NO20050764L true NO20050764L (no) 2005-02-11

Family

ID=9940462

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050764A NO20050764L (no) 2002-07-13 2005-02-11 Forbindelser

Country Status (16)

Country Link
US (1) US20060063783A1 (no)
EP (1) EP1531821A2 (no)
JP (1) JP2006502990A (no)
CN (1) CN1668302A (no)
AU (1) AU2003246933A1 (no)
BR (1) BR0312615A (no)
CA (1) CA2492251A1 (no)
GB (1) GB0216382D0 (no)
IL (1) IL166011A0 (no)
IS (1) IS7656A (no)
MX (1) MXPA05000517A (no)
NO (1) NO20050764L (no)
PL (1) PL375361A1 (no)
RU (1) RU2004139043A (no)
WO (1) WO2004006927A2 (no)
ZA (1) ZA200500210B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60230781D1 (en) 2001-09-07 2009-02-26 Kaken Pharma Co Ltd Reverse hydroxamsäurederivate
EP2041181B1 (en) * 2006-06-08 2011-05-18 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Specific protease inhibitors and their use in cancer therapy
RU2569851C2 (ru) * 2010-07-08 2015-11-27 Какен Фармасьютикал Ко., Лтд. Производное n-гидроксиформамида и содержащее его лекарственное средство
JP5876828B2 (ja) 2010-09-17 2016-03-02 国立大学法人 東京大学 血小板の機能を維持するための組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024399A1 (en) * 1997-11-12 1999-05-20 Darwin Discovery Limited Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
EE200100410A (et) * 1999-02-08 2002-12-16 G.D. Searle & Co. Sulfamaathüdroksaamhappe metalloproteaasi inhibiitor

Also Published As

Publication number Publication date
CN1668302A (zh) 2005-09-14
JP2006502990A (ja) 2006-01-26
GB0216382D0 (en) 2002-08-21
US20060063783A1 (en) 2006-03-23
EP1531821A2 (en) 2005-05-25
BR0312615A (pt) 2005-04-19
IS7656A (is) 2005-01-20
CA2492251A1 (en) 2004-01-22
RU2004139043A (ru) 2005-10-10
WO2004006927A3 (en) 2004-03-25
AU2003246933A1 (en) 2004-02-02
WO2004006927A2 (en) 2004-01-22
PL375361A1 (en) 2005-11-28
MXPA05000517A (es) 2005-03-23
ZA200500210B (en) 2005-11-02
IL166011A0 (en) 2006-01-15

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