IS7656A - Súlfónýlpíperidínafleiður sem innihalda alkenýl- eða alkýnýlhelft til að nota sem hemla fyrir stoðefnismálmpróteasa - Google Patents

Súlfónýlpíperidínafleiður sem innihalda alkenýl- eða alkýnýlhelft til að nota sem hemla fyrir stoðefnismálmpróteasa

Info

Publication number
IS7656A
IS7656A IS7656A IS7656A IS7656A IS 7656 A IS7656 A IS 7656A IS 7656 A IS7656 A IS 7656A IS 7656 A IS7656 A IS 7656A IS 7656 A IS7656 A IS 7656A
Authority
IS
Iceland
Prior art keywords
protease
sulphonylpiperidine
alkenyl
inhibitors
derivatives containing
Prior art date
Application number
IS7656A
Other languages
English (en)
Inventor
Nicholas Burrows Jeremy
Tucker Howard
James Brown Simon
Patel Ian
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS7656A publication Critical patent/IS7656A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS7656A 2002-07-13 2005-01-20 Súlfónýlpíperidínafleiður sem innihalda alkenýl- eða alkýnýlhelft til að nota sem hemla fyrir stoðefnismálmpróteasa IS7656A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216382.2A GB0216382D0 (en) 2002-07-13 2002-07-13 Compounds
PCT/GB2003/002985 WO2004006927A2 (en) 2002-07-13 2003-07-09 Sulphonylpiperidine derivatives containing an alkenyl or alkynly moiety for use as matrix metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
IS7656A true IS7656A (is) 2005-01-20

Family

ID=9940462

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7656A IS7656A (is) 2002-07-13 2005-01-20 Súlfónýlpíperidínafleiður sem innihalda alkenýl- eða alkýnýlhelft til að nota sem hemla fyrir stoðefnismálmpróteasa

Country Status (16)

Country Link
US (1) US20060063783A1 (is)
EP (1) EP1531821A2 (is)
JP (1) JP2006502990A (is)
CN (1) CN1668302A (is)
AU (1) AU2003246933A1 (is)
BR (1) BR0312615A (is)
CA (1) CA2492251A1 (is)
GB (1) GB0216382D0 (is)
IL (1) IL166011A0 (is)
IS (1) IS7656A (is)
MX (1) MXPA05000517A (is)
NO (1) NO20050764L (is)
PL (1) PL375361A1 (is)
RU (1) RU2004139043A (is)
WO (1) WO2004006927A2 (is)
ZA (1) ZA200500210B (is)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459380C (en) 2001-09-07 2010-11-23 Kaken Pharmaceutical Co., Ltd. Reverse hydroxamic acid derivatives
EP2041181B1 (en) * 2006-06-08 2011-05-18 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Specific protease inhibitors and their use in cancer therapy
HUE030114T2 (en) * 2010-07-08 2017-04-28 Kaken Pharma Co Ltd N-hydroxyformamide derivatives and pharmaceutical compositions containing them
RU2578607C2 (ru) * 2010-09-17 2016-03-27 Дзе Юниверсити Оф Токио Композиция для поддержания функции тромбоцитов

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL135921A (en) * 1997-11-12 2005-08-31 Darwin Discovery Ltd Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
US6448250B1 (en) * 1999-02-08 2002-09-10 G. D. Searle & Company Sulfamato hydroxamic acid metalloprotease inhibitor

Also Published As

Publication number Publication date
AU2003246933A1 (en) 2004-02-02
WO2004006927A3 (en) 2004-03-25
CA2492251A1 (en) 2004-01-22
ZA200500210B (en) 2005-11-02
MXPA05000517A (es) 2005-03-23
NO20050764L (no) 2005-02-11
GB0216382D0 (en) 2002-08-21
IL166011A0 (en) 2006-01-15
PL375361A1 (en) 2005-11-28
CN1668302A (zh) 2005-09-14
US20060063783A1 (en) 2006-03-23
EP1531821A2 (en) 2005-05-25
RU2004139043A (ru) 2005-10-10
WO2004006927A2 (en) 2004-01-22
JP2006502990A (ja) 2006-01-26
BR0312615A (pt) 2005-04-19

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