NO20034559L - Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon - Google Patents

Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon

Info

Publication number
NO20034559L
NO20034559L NO20034559A NO20034559A NO20034559L NO 20034559 L NO20034559 L NO 20034559L NO 20034559 A NO20034559 A NO 20034559A NO 20034559 A NO20034559 A NO 20034559A NO 20034559 L NO20034559 L NO 20034559L
Authority
NO
Norway
Prior art keywords
mice
isolation
identification
controls associated
human transcriptional
Prior art date
Application number
NO20034559A
Other languages
English (en)
Norwegian (no)
Other versions
NO20034559D0 (no
Inventor
Weisheng Zhang
Pamela Contag
Anthony Purchio
Sandy Hashima
Shirley Ma
Kevin A Nawotka
Original Assignee
Xenogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenogen Corp filed Critical Xenogen Corp
Publication of NO20034559D0 publication Critical patent/NO20034559D0/no
Publication of NO20034559L publication Critical patent/NO20034559L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO20034559A 2001-04-12 2003-10-10 Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon NO20034559L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28353401P 2001-04-12 2001-04-12
PCT/US2002/011770 WO2002088305A2 (fr) 2001-04-12 2002-04-11 Isolation et identification d'elements regulateurs de transcription murins et humains associes a l'expression de cytochromes

Publications (2)

Publication Number Publication Date
NO20034559D0 NO20034559D0 (no) 2003-10-10
NO20034559L true NO20034559L (no) 2003-12-11

Family

ID=23086490

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034559A NO20034559L (no) 2001-04-12 2003-10-10 Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon

Country Status (6)

Country Link
US (1) US7449567B2 (fr)
EP (1) EP1390744B1 (fr)
JP (2) JP2005510205A (fr)
AU (1) AU2002338573B2 (fr)
NO (1) NO20034559L (fr)
WO (1) WO2002088305A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP362898A0 (en) * 1998-05-21 1998-06-11 University Of Sydney, The Xenobiotic induction of gene expression
AUPR116100A0 (en) 2000-11-01 2000-11-23 University Of Sydney, The P450 gene regulation
CA2426959C (fr) * 2000-11-01 2011-10-04 The University Of Sydney Animaux transgeniques utilises pour analyser la regulation du gene p450 du cytochrome cyp3a4
WO2002088305A2 (fr) 2001-04-12 2002-11-07 Xenogen Corporation Isolation et identification d'elements regulateurs de transcription murins et humains associes a l'expression de cytochromes
JP4572320B2 (ja) * 2004-02-23 2010-11-04 財団法人大阪産業振興機構 組換えヒト細胞、ならびにその組換えヒト細胞を用いてヒト薬物代謝酵素の誘導および薬物代謝の少なくとも一方を評価する方法
EP2478113B1 (fr) 2009-09-18 2020-09-02 Caliper Life Sciences, Inc. Compositions et procédés pour l'évaluation de bioluminescence in vivo
WO2012030981A1 (fr) 2010-09-01 2012-03-08 Spectral Instruments Imaging, LLC Assemblage de sources de lumière d'excitation
US9347894B2 (en) 2010-09-01 2016-05-24 Spectral Instruments Imaging, LLC Methods and systems for producing visible light and x-ray image data
EP2618849B1 (fr) 2010-09-20 2020-10-21 Caliper Life Sciences, Inc. Sondes fluorescentes multivalentes
EP3673923B1 (fr) 2011-04-13 2023-08-30 Caliper Life Sciences, Inc. Imagerie in vivo de l'activité enzymatique
US20150284812A1 (en) * 2012-10-19 2015-10-08 National University Corporation Tottori University Method for evaluating both induction of drug-metabolizing enzyme and cytotoxicity, and vector and cell for use in said method

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997757A (en) 1987-12-23 1991-03-05 Genebiomed, Inc. Process for detecting potential carcinogens
US6432639B1 (en) 1997-09-10 2002-08-13 Dna Sciences Laboratories, Inc. Isolated CYP3A4 nucleic acid molecules and detection methods
AUPP362898A0 (en) 1998-05-21 1998-06-11 University Of Sydney, The Xenobiotic induction of gene expression
AU6476000A (en) 1999-08-13 2001-03-13 Kirin Beer Kabushiki Kaisha Mouse having human cytochrome p450 transferred therein
EP1088900A1 (fr) 1999-09-10 2001-04-04 Epidauros Biotechnologie AG Polymorphismes des gènes humaines CYP3A4, CYP3A7 et hPXR et leur utilisation pour des applications diagnostiques et thérapeutiques
AU2001285842A1 (en) 2000-07-25 2002-02-05 Epidauros Biotechnologie Ag Assay for screening compounds for inducing drug metabolizing enzymes
AU2001291192B2 (en) 2000-09-21 2006-11-30 Baylor College Of Medicine Screening systems and methods for identifying modulators of xenobiotic metabolism
US20020150915A1 (en) 2000-09-22 2002-10-17 Anders Berkenstam Promoter sequences
CA2426959C (fr) * 2000-11-01 2011-10-04 The University Of Sydney Animaux transgeniques utilises pour analyser la regulation du gene p450 du cytochrome cyp3a4
WO2002088305A2 (fr) 2001-04-12 2002-11-07 Xenogen Corporation Isolation et identification d'elements regulateurs de transcription murins et humains associes a l'expression de cytochromes
AUPR446701A0 (en) 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies

Also Published As

Publication number Publication date
JP2005510205A (ja) 2005-04-21
US7449567B2 (en) 2008-11-11
AU2002338573B2 (en) 2007-07-05
WO2002088305A2 (fr) 2002-11-07
EP1390744B1 (fr) 2012-09-26
EP1390744A2 (fr) 2004-02-25
WO2002088305A3 (fr) 2003-12-11
US20030145341A1 (en) 2003-07-31
EP1390744A4 (fr) 2006-07-26
NO20034559D0 (no) 2003-10-10
JP2008188024A (ja) 2008-08-21

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