NO20034559L - Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon - Google Patents

Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon

Info

Publication number
NO20034559L
NO20034559L NO20034559A NO20034559A NO20034559L NO 20034559 L NO20034559 L NO 20034559L NO 20034559 A NO20034559 A NO 20034559A NO 20034559 A NO20034559 A NO 20034559A NO 20034559 L NO20034559 L NO 20034559L
Authority
NO
Norway
Prior art keywords
mice
isolation
identification
controls associated
human transcriptional
Prior art date
Application number
NO20034559A
Other languages
English (en)
Other versions
NO20034559D0 (no
Inventor
Weisheng Zhang
Pamela Contag
Anthony Purchio
Sandy Hashima
Shirley Ma
Kevin A Nawotka
Original Assignee
Xenogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenogen Corp filed Critical Xenogen Corp
Publication of NO20034559D0 publication Critical patent/NO20034559D0/no
Publication of NO20034559L publication Critical patent/NO20034559L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0393Animal model comprising a reporter system for screening tests
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Environmental Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO20034559A 2001-04-12 2003-10-10 Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon NO20034559L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28353401P 2001-04-12 2001-04-12
PCT/US2002/011770 WO2002088305A2 (en) 2001-04-12 2002-04-11 Isolation and identification of mouse and human transcription control elements associated with cytochrome expression

Publications (2)

Publication Number Publication Date
NO20034559D0 NO20034559D0 (no) 2003-10-10
NO20034559L true NO20034559L (no) 2003-12-11

Family

ID=23086490

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034559A NO20034559L (no) 2001-04-12 2003-10-10 Isolering og identifikasjon av mus og humane transkripsjonskontrollelementer som er forbundet med cytokromekspresjon

Country Status (6)

Country Link
US (1) US7449567B2 (no)
EP (1) EP1390744B1 (no)
JP (2) JP2005510205A (no)
AU (1) AU2002338573B2 (no)
NO (1) NO20034559L (no)
WO (1) WO2002088305A2 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP362898A0 (en) * 1998-05-21 1998-06-11 University Of Sydney, The Xenobiotic induction of gene expression
AUPR116100A0 (en) 2000-11-01 2000-11-23 University Of Sydney, The P450 gene regulation
EP1337650A4 (en) * 2000-11-01 2005-12-21 Univ Sydney TRANSGENIC ANIMALS USED TO ANALYZE CYP3A4 CYTOCHROME P450 GENE REGULATION
JP2005510205A (ja) 2001-04-12 2005-04-21 ゼノジェン コーポレイション チトクロム発現に関連するマウスおよびヒト転写制御エレメントの単離および同定
JP4572320B2 (ja) * 2004-02-23 2010-11-04 財団法人大阪産業振興機構 組換えヒト細胞、ならびにその組換えヒト細胞を用いてヒト薬物代謝酵素の誘導および薬物代謝の少なくとも一方を評価する方法
EP4151746A1 (en) 2009-09-18 2023-03-22 Caliper Life Sciences, Inc. Compositions and methods for in vivo evaluation of bioluminescence
WO2012030973A2 (en) 2010-09-01 2012-03-08 Spectral Instruments Imaging, LLC Methods and systems for producing visible light and x-ray image data
US8901516B2 (en) 2010-09-01 2014-12-02 Spectral Instruments Imaging, LLC Excitation light source assembly
US9012242B2 (en) 2010-09-20 2015-04-21 Caliper Life Sciences Multivalent fluorescent probes
JP6084203B2 (ja) 2011-04-13 2017-02-22 キャリパー ライフ サイエンシーズ, インコーポレイテッド 酵素活性のインビボでの画像化
WO2014061829A1 (ja) * 2012-10-19 2014-04-24 国立大学法人鳥取大学 薬物代謝酵素誘導および細胞毒性の評価方法、ならびにそのためのベクターおよび細胞

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997757A (en) * 1987-12-23 1991-03-05 Genebiomed, Inc. Process for detecting potential carcinogens
US6432639B1 (en) * 1997-09-10 2002-08-13 Dna Sciences Laboratories, Inc. Isolated CYP3A4 nucleic acid molecules and detection methods
AUPP362898A0 (en) 1998-05-21 1998-06-11 University Of Sydney, The Xenobiotic induction of gene expression
AU6476000A (en) 1999-08-13 2001-03-13 Kirin Beer Kabushiki Kaisha Mouse having human cytochrome p450 transferred therein
EP1088900A1 (en) 1999-09-10 2001-04-04 Epidauros Biotechnologie AG Polymorphisms in the human CYP3A4, CYP3A7 and hPXR genes and their use in diagnostic and therapeutic applications
WO2002008451A2 (en) * 2000-07-25 2002-01-31 Epidauros Biotechnologie Ag Assay for screening compounds for inducing drug metabolizing enzymes
AU2001291192B2 (en) 2000-09-21 2006-11-30 Baylor College Of Medicine Screening systems and methods for identifying modulators of xenobiotic metabolism
US20020150915A1 (en) 2000-09-22 2002-10-17 Anders Berkenstam Promoter sequences
EP1337650A4 (en) 2000-11-01 2005-12-21 Univ Sydney TRANSGENIC ANIMALS USED TO ANALYZE CYP3A4 CYTOCHROME P450 GENE REGULATION
JP2005510205A (ja) 2001-04-12 2005-04-21 ゼノジェン コーポレイション チトクロム発現に関連するマウスおよびヒト転写制御エレメントの単離および同定
AUPR446701A0 (en) 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies

Also Published As

Publication number Publication date
JP2005510205A (ja) 2005-04-21
US20030145341A1 (en) 2003-07-31
WO2002088305A2 (en) 2002-11-07
NO20034559D0 (no) 2003-10-10
WO2002088305A3 (en) 2003-12-11
JP2008188024A (ja) 2008-08-21
US7449567B2 (en) 2008-11-11
EP1390744B1 (en) 2012-09-26
EP1390744A4 (en) 2006-07-26
EP1390744A2 (en) 2004-02-25
AU2002338573B2 (en) 2007-07-05

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