NO20020592D0 - Fluorine derivatives as integrin inhibitors - Google Patents

Fluorine derivatives as integrin inhibitors

Info

Publication number
NO20020592D0
NO20020592D0 NO20020592A NO20020592A NO20020592D0 NO 20020592 D0 NO20020592 D0 NO 20020592D0 NO 20020592 A NO20020592 A NO 20020592A NO 20020592 A NO20020592 A NO 20020592A NO 20020592 D0 NO20020592 D0 NO 20020592D0
Authority
NO
Norway
Prior art keywords
integrin inhibitors
fluorine derivatives
fluorine
derivatives
integrin
Prior art date
Application number
NO20020592A
Other languages
Norwegian (no)
Other versions
NO20020592L (en
Inventor
Wolfgang Staehle
Simon Goodman
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20020592D0 publication Critical patent/NO20020592D0/en
Publication of NO20020592L publication Critical patent/NO20020592L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
NO20020592A 1999-08-07 2002-02-06 Fluorine derivatives as integrin inhibitors NO20020592L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19937394A DE19937394A1 (en) 1999-08-07 1999-08-07 Fluorene derivatives
PCT/EP2000/007153 WO2001010841A2 (en) 1999-08-07 2000-07-26 Fluorene derivatives as integrin inhibitors

Publications (2)

Publication Number Publication Date
NO20020592D0 true NO20020592D0 (en) 2002-02-06
NO20020592L NO20020592L (en) 2002-04-04

Family

ID=7917613

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020592A NO20020592L (en) 1999-08-07 2002-02-06 Fluorine derivatives as integrin inhibitors

Country Status (18)

Country Link
EP (1) EP1208088A2 (en)
JP (1) JP2003506439A (en)
KR (1) KR20020012631A (en)
CN (1) CN1368962A (en)
AR (1) AR025042A1 (en)
AU (1) AU6828600A (en)
BR (1) BR0013083A (en)
CA (1) CA2380981A1 (en)
CZ (1) CZ2002298A3 (en)
DE (1) DE19937394A1 (en)
HK (1) HK1049006A1 (en)
HU (1) HUP0202464A3 (en)
MX (1) MXPA02001297A (en)
NO (1) NO20020592L (en)
PL (1) PL353054A1 (en)
SK (1) SK1402002A3 (en)
WO (1) WO2001010841A2 (en)
ZA (1) ZA200201873B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101102808B1 (en) * 2010-04-13 2012-01-05 윤태삼 Riser tensioner
US8574899B2 (en) 2010-12-22 2013-11-05 Vladimir B Serikov Methods for augmentation collection of placental hematopoietic stem cells and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2058925A1 (en) * 1989-06-22 1990-12-23 Moshe Weitzberg Pharmaceutical compositions and methods for treating inflammation
IL113196A0 (en) * 1994-03-31 1995-06-29 Bristol Myers Squibb Co Imidazole derivatives and pharmaceutical compositions containing the same
WO1997036862A1 (en) * 1996-03-29 1997-10-09 G.D. Searle & Co. META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS
DE19654483A1 (en) * 1996-06-28 1998-01-02 Merck Patent Gmbh Phenylalanine derivatives
CA2214931A1 (en) * 1996-09-26 1998-03-26 Henry Uhlman Bryant Tetrahydrobenzo-a-fluorene compounds and method of use

Also Published As

Publication number Publication date
WO2001010841A2 (en) 2001-02-15
SK1402002A3 (en) 2002-06-04
NO20020592L (en) 2002-04-04
DE19937394A1 (en) 2001-02-08
HUP0202464A3 (en) 2003-02-28
PL353054A1 (en) 2003-10-06
EP1208088A2 (en) 2002-05-29
KR20020012631A (en) 2002-02-16
AU6828600A (en) 2001-03-05
CZ2002298A3 (en) 2002-04-17
MXPA02001297A (en) 2004-07-16
JP2003506439A (en) 2003-02-18
HUP0202464A2 (en) 2002-12-28
HK1049006A1 (en) 2003-04-25
AR025042A1 (en) 2002-11-06
BR0013083A (en) 2002-04-23
CA2380981A1 (en) 2001-02-15
CN1368962A (en) 2002-09-11
ZA200201873B (en) 2003-08-27
WO2001010841A3 (en) 2001-09-07

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application