DK1222193T3 - Imidazole derivatives as phosphodiesterase VII inhibitors - Google Patents
Imidazole derivatives as phosphodiesterase VII inhibitorsInfo
- Publication number
- DK1222193T3 DK1222193T3 DK00972714T DK00972714T DK1222193T3 DK 1222193 T3 DK1222193 T3 DK 1222193T3 DK 00972714 T DK00972714 T DK 00972714T DK 00972714 T DK00972714 T DK 00972714T DK 1222193 T3 DK1222193 T3 DK 1222193T3
- Authority
- DK
- Denmark
- Prior art keywords
- imidazole derivatives
- phosphodiesterase vii
- vii inhibitors
- inhibitors
- phosphodiesterase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19950647A DE19950647A1 (en) | 1999-10-21 | 1999-10-21 | Benzopyranoimidazolone and benzothiopyranoimidazolone derivatives as phosphodiesterase-VII inhibitors useful for treatment of e.g. asthma, psoriasis, osteoporosis, cachexia, sepsis, tumors and AIDS |
PCT/EP2000/009926 WO2001029049A2 (en) | 1999-10-21 | 2000-10-10 | Imidazole derivatives as phosphodiesterase vii inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1222193T3 true DK1222193T3 (en) | 2003-12-01 |
Family
ID=7926352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00972714T DK1222193T3 (en) | 1999-10-21 | 2000-10-10 | Imidazole derivatives as phosphodiesterase VII inhibitors |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1222193B1 (en) |
JP (1) | JP2003512381A (en) |
KR (1) | KR20020060201A (en) |
CN (1) | CN1382146A (en) |
AR (1) | AR026198A1 (en) |
AT (1) | ATE247121T1 (en) |
AU (1) | AU780788B2 (en) |
BR (1) | BR0014922A (en) |
CA (1) | CA2388314C (en) |
CZ (1) | CZ293751B6 (en) |
DE (2) | DE19950647A1 (en) |
DK (1) | DK1222193T3 (en) |
ES (1) | ES2200957T3 (en) |
HU (1) | HUP0203139A3 (en) |
MX (1) | MXPA02003952A (en) |
NO (1) | NO20021846D0 (en) |
PL (1) | PL355020A1 (en) |
PT (1) | PT1222193E (en) |
RU (1) | RU2259199C2 (en) |
SK (1) | SK4922002A3 (en) |
WO (1) | WO2001029049A2 (en) |
ZA (1) | ZA200203995B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0207215A (en) | 2001-12-13 | 2004-02-10 | Daiichi Suntory Pharma Co Ltd | Pyrazolopyriminone derivatives having pde7 inhibition action |
DE10163991A1 (en) * | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | Pyrrolo-pyrimidine |
JP2006219373A (en) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Pyridinylpyrazolopyrimidinone derivative having pde 7 inhibition |
JP2006219374A (en) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Imidazotriazinone derivative having pde 7 inhibition |
JP4810426B2 (en) | 2004-07-01 | 2011-11-09 | 第一三共株式会社 | Thienopyrazole derivative having PDE7 inhibitory action |
CN101917992A (en) | 2007-03-27 | 2010-12-15 | 奥默罗斯公司 | Use of PDE7 inhibitors for the treatment of movement disorders |
US8637528B2 (en) | 2007-03-27 | 2014-01-28 | Omeros Corporation | Use of PDE7 inhibitors for the treatment of movement disorders |
US9220715B2 (en) | 2010-11-08 | 2015-12-29 | Omeros Corporation | Treatment of addiction and impulse-control disorders using PDE7 inhibitors |
CN103547267A (en) | 2010-11-08 | 2014-01-29 | 奥默罗斯公司 | Treatment of addiction and impulse-control disorders using PDE7 inhibitors |
WO2024038090A1 (en) | 2022-08-18 | 2024-02-22 | Mitodicure Gmbh | Use of substituted benzoxazole and benzofuran compounds for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4305954A (en) * | 1981-02-11 | 1981-12-15 | E. I. Du Pont De Nemours And Company | Antiinflammatory 3,4-dihydro(or 1,4-dihydro)-2-[(substituted)thio]-[1]benzopyrano[3,4-d]imidazoles and their corresponding sulfoxides and sulfones |
WO2000023091A2 (en) * | 1998-10-15 | 2000-04-27 | Bioimage A/S | Specific therapeutic interventions obtained by interference with redistribution and/or targeting of cyclic nucleotide phosphodiesterases of i-kappa-b kinases |
AU4589800A (en) * | 1999-05-05 | 2000-11-21 | Darwin Discovery Limited | 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors |
-
1999
- 1999-10-21 DE DE19950647A patent/DE19950647A1/en not_active Withdrawn
-
2000
- 2000-10-10 KR KR1020027004903A patent/KR20020060201A/en not_active Application Discontinuation
- 2000-10-10 CZ CZ20021251A patent/CZ293751B6/en not_active IP Right Cessation
- 2000-10-10 RU RU2002111413/15A patent/RU2259199C2/en not_active IP Right Cessation
- 2000-10-10 AT AT00972714T patent/ATE247121T1/en not_active IP Right Cessation
- 2000-10-10 MX MXPA02003952A patent/MXPA02003952A/en unknown
- 2000-10-10 SK SK492-2002A patent/SK4922002A3/en unknown
- 2000-10-10 DK DK00972714T patent/DK1222193T3/en active
- 2000-10-10 PL PL00355020A patent/PL355020A1/en unknown
- 2000-10-10 ES ES00972714T patent/ES2200957T3/en not_active Expired - Lifetime
- 2000-10-10 CN CN00814402A patent/CN1382146A/en active Pending
- 2000-10-10 WO PCT/EP2000/009926 patent/WO2001029049A2/en active IP Right Grant
- 2000-10-10 CA CA002388314A patent/CA2388314C/en not_active Expired - Fee Related
- 2000-10-10 PT PT00972714T patent/PT1222193E/en unknown
- 2000-10-10 BR BR0014922-5A patent/BR0014922A/en not_active IP Right Cessation
- 2000-10-10 AU AU11356/01A patent/AU780788B2/en not_active Ceased
- 2000-10-10 DE DE50003309T patent/DE50003309D1/en not_active Expired - Lifetime
- 2000-10-10 HU HU0203139A patent/HUP0203139A3/en unknown
- 2000-10-10 EP EP00972714A patent/EP1222193B1/en not_active Expired - Lifetime
- 2000-10-10 JP JP2001531847A patent/JP2003512381A/en active Pending
- 2000-10-20 AR ARP000105542A patent/AR026198A1/en unknown
-
2002
- 2002-04-19 NO NO20021846A patent/NO20021846D0/en not_active Application Discontinuation
- 2002-05-20 ZA ZA200203995A patent/ZA200203995B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU1135601A (en) | 2001-04-30 |
CZ293751B6 (en) | 2004-07-14 |
CN1382146A (en) | 2002-11-27 |
ES2200957T3 (en) | 2004-03-16 |
NO20021846L (en) | 2002-04-19 |
EP1222193A2 (en) | 2002-07-17 |
EP1222193B1 (en) | 2003-08-13 |
ZA200203995B (en) | 2003-10-29 |
JP2003512381A (en) | 2003-04-02 |
MXPA02003952A (en) | 2004-09-06 |
CA2388314C (en) | 2009-06-16 |
PT1222193E (en) | 2003-12-31 |
WO2001029049A2 (en) | 2001-04-26 |
CA2388314A1 (en) | 2001-04-26 |
ATE247121T1 (en) | 2003-08-15 |
DE50003309D1 (en) | 2003-09-18 |
SK4922002A3 (en) | 2002-09-10 |
KR20020060201A (en) | 2002-07-16 |
HUP0203139A2 (en) | 2003-01-28 |
DE19950647A1 (en) | 2001-04-26 |
AU780788B2 (en) | 2005-04-14 |
NO20021846D0 (en) | 2002-04-19 |
CZ20021251A3 (en) | 2002-07-17 |
HUP0203139A3 (en) | 2004-12-28 |
PL355020A1 (en) | 2004-03-22 |
WO2001029049A3 (en) | 2001-11-01 |
AR026198A1 (en) | 2003-01-29 |
RU2259199C2 (en) | 2005-08-27 |
BR0014922A (en) | 2002-06-11 |
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