NO20013586D0 - Bis-sulfonamider - Google Patents

Bis-sulfonamider

Info

Publication number
NO20013586D0
NO20013586D0 NO20013586A NO20013586A NO20013586D0 NO 20013586 D0 NO20013586 D0 NO 20013586D0 NO 20013586 A NO20013586 A NO 20013586A NO 20013586 A NO20013586 A NO 20013586A NO 20013586 D0 NO20013586 D0 NO 20013586D0
Authority
NO
Norway
Prior art keywords
lower alkyl
heteroaryl
aryl
heterocyclyl
alkyl
Prior art date
Application number
NO20013586A
Other languages
English (en)
Norwegian (no)
Other versions
NO20013586L (no
Inventor
Martin Bolli
Christoph Boss
Martine Clozel
Walter Fischli
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of NO20013586D0 publication Critical patent/NO20013586D0/no
Publication of NO20013586L publication Critical patent/NO20013586L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69—Benzenesulfonamido-pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
NO20013586A 1999-09-03 2001-07-20 Bis-sulfonamider NO20013586L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP9906485 1999-09-03
EP0001222 2000-02-15
PCT/EP2000/007999 WO2001017976A1 (fr) 1999-09-03 2000-08-16 Bis-sulfonamides

Publications (2)

Publication Number Publication Date
NO20013586D0 true NO20013586D0 (no) 2001-07-20
NO20013586L NO20013586L (no) 2001-07-20

Family

ID=8167417

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013586A NO20013586L (no) 1999-09-03 2001-07-20 Bis-sulfonamider

Country Status (14)

Country Link
US (1) US6596719B1 (fr)
EP (1) EP1137642B1 (fr)
CN (1) CN100424079C (fr)
AT (1) ATE380180T1 (fr)
AU (1) AU775194B2 (fr)
CA (1) CA2361402C (fr)
DE (1) DE60037308T2 (fr)
ES (1) ES2295048T3 (fr)
HU (1) HUP0201402A3 (fr)
IL (1) IL143935A (fr)
NO (1) NO20013586L (fr)
NZ (1) NZ512526A (fr)
WO (1) WO2001017976A1 (fr)
ZA (1) ZA200105130B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720322B2 (en) * 1999-12-22 2004-04-13 Actelion Pharamceuticals Ltd. Butyne diol derivatives
AU2001241512A1 (en) * 2000-03-13 2001-09-24 Eli Lilly And Company Sulfonamide derivatives
US6387915B2 (en) 2000-05-31 2002-05-14 Pfizer Inc. Isoxazole-sulfonamide endothelin antagonists
NZ525614A (en) * 2000-12-18 2005-03-24 Actelion Pharmaceuticals Ltd Novel sulfamides and their use as endothelin receptor antagonists
ES2262567T3 (es) 2001-03-20 2006-12-01 Schwarz Pharma Ag Nuevo uso de una clase peptidica de compuesto para tratamiento del dolor inflamatorio no neuropatico.
ES2185606T3 (es) 2001-03-21 2003-05-01 Sanol Arznei Schwarz Gmbh Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma.
NZ533693A (en) * 2002-01-02 2007-02-23 Actelion Pharmaceuticals Ltd Alkansulfonamides as endothelin receptor antagonists
JP4664924B2 (ja) 2003-12-02 2011-04-06 ウーツェーベー ファルマ ゲーエムベーハー 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用
WO2005095359A1 (fr) 2004-03-05 2005-10-13 F. Hoffmann-La Roche Ag Diaminopyrimidines utilisees en tant qu'antagonistes de p2x3 et p2x2/3
US8008351B2 (en) 2004-04-16 2011-08-30 Ucb Pharma Gmbh Methods for prophylaxis or treatment of conditions associated with cortical spreading depression
EP1604655A1 (fr) 2004-06-09 2005-12-14 Schwarz Pharma Ag Utilisation nouvelle de peptides pour le traitement de neuralgies trigeminales
NZ552651A (en) 2004-08-27 2010-07-30 Sanol Arznei Schwarz Gmbh Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain
JP4850913B2 (ja) 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３及びｐ２ｘ２／３調節因子としてのジアミノピリジン
CN101296907B (zh) 2005-09-01 2013-03-27 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类
AU2006286576B2 (en) 2005-09-01 2012-06-14 F. Hoffmann-La Roche Ag Diaminopyrimidines as P2X3 and P3X2/3 modulators
EP2037965B1 (fr) 2006-06-15 2017-08-30 UCB Pharma GmbH Composition pharmaceutique ayant un effet anticonvulsivant synergique
AR062501A1 (es) 2006-08-29 2008-11-12 Actelion Pharmaceuticals Ltd Composiciones terapeuticas
MX2010001837A (es) 2007-08-17 2010-03-10 Actelion Pharmaceuticals Ltd Derivados de 4-pirimidinasulfamida.
CN101279948B (zh) * 2008-03-14 2010-08-11 苏州博鸿化工技术有限公司 4,6-二氯-5-(2-甲氧基苯氧基)-2,2'-二嘧啶的合成方法
CN111407767B (zh) * 2020-03-28 2021-05-25 中山大学 一种磺胺间甲氧嘧啶衍生物在制备抗肿瘤药物中的应用
CN112898208B (zh) * 2021-01-29 2023-06-20 中国医科大学 苯基嘧啶胺类抗肿瘤化合物及其制备方法和应用
CN112778215B (zh) * 2021-01-29 2023-06-20 中国医科大学 2-甲氧基苯氧基嘧啶类抗肿瘤化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7310889A (fr) * 1972-08-12 1974-02-14
CA2162630C (fr) * 1994-11-25 2007-05-01 Volker Breu Sulfonamides
TW313568B (fr) 1994-12-20 1997-08-21 Hoffmann La Roche
US5739333A (en) 1995-05-16 1998-04-14 Tanabe Seiyaku Co., Ltd. Sulfonamide derivative and process for preparing the same
US5939446A (en) * 1996-04-09 1999-08-17 Bristol-Myers Squibb Co. Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists

Also Published As

Publication number Publication date
AU775194B2 (en) 2004-07-22
HUP0201402A3 (en) 2003-12-29
CA2361402A1 (fr) 2001-03-15
DE60037308D1 (de) 2008-01-17
HUP0201402A2 (en) 2002-08-28
CN1335839A (zh) 2002-02-13
ES2295048T3 (es) 2008-04-16
NZ512526A (en) 2004-01-30
DE60037308T2 (de) 2008-10-30
ZA200105130B (en) 2002-09-23
EP1137642B1 (fr) 2007-12-05
AU6839100A (en) 2001-04-10
EP1137642A1 (fr) 2001-10-04
ATE380180T1 (de) 2007-12-15
IL143935A (en) 2005-08-31
CN100424079C (zh) 2008-10-08
WO2001017976A1 (fr) 2001-03-15
NO20013586L (no) 2001-07-20
IL143935A0 (en) 2002-04-21
US6596719B1 (en) 2003-07-22
CA2361402C (fr) 2009-05-12

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Legal Events

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RE Reestablishment of rights (par. 72 patents act)
FC2A Withdrawal, rejection or dismissal of laid open patent application