NO20012114L - Chaperonekompleks med <beta>-amyloid og anvendelse av komplekset - Google Patents
Chaperonekompleks med <beta>-amyloid og anvendelse av kompleksetInfo
- Publication number
- NO20012114L NO20012114L NO20012114A NO20012114A NO20012114L NO 20012114 L NO20012114 L NO 20012114L NO 20012114 A NO20012114 A NO 20012114A NO 20012114 A NO20012114 A NO 20012114A NO 20012114 L NO20012114 L NO 20012114L
- Authority
- NO
- Norway
- Prior art keywords
- disease
- complex
- level
- alzheimer
- amyloid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10639898P | 1998-10-30 | 1998-10-30 | |
US12356499P | 1999-03-10 | 1999-03-10 | |
PCT/US1999/025593 WO2000026251A2 (en) | 1998-10-30 | 1999-10-29 | A COMPLEX OF A CHAPERONE WITH ss-AMYLOID AND METHODS EMPLOYING THIS COMPLEX |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20012114D0 NO20012114D0 (no) | 2001-04-27 |
NO20012114L true NO20012114L (no) | 2001-06-14 |
NO331974B1 NO331974B1 (no) | 2012-05-14 |
Family
ID=26803625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20012114A NO331974B1 (no) | 1998-10-30 | 2001-04-27 | Fremgangsmate for a detektere i en biologisk prove et kompleks av chaperon Q2 og beta-amyloid, antistoff som gjenkjenner komplekset og anvendelse av chaperon Q2 for fremstilling av et preparat for behandling av Alzheimers sykdom. |
Country Status (12)
Country | Link |
---|---|
US (3) | US6972318B1 (no) |
EP (1) | EP1125135B1 (no) |
JP (1) | JP4571310B2 (no) |
AT (1) | ATE284538T1 (no) |
AU (1) | AU764713B2 (no) |
CA (1) | CA2348545C (no) |
DE (1) | DE69922535T2 (no) |
IL (2) | IL142852A0 (no) |
MX (1) | MXPA01004317A (no) |
NO (1) | NO331974B1 (no) |
NZ (1) | NZ511589A (no) |
WO (1) | WO2000026251A2 (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL153058A0 (en) * | 2000-05-24 | 2003-06-24 | Jordan Loyal Holtzman | Agents and methods for increasing brain chaperonin levels |
US7094757B2 (en) | 2001-06-22 | 2006-08-22 | Roche Diagnostics Corporation | Complexes comprising a prion protein and a peptidyl prolyl isomerase chaperone, and method for producing and using them |
US7094884B2 (en) | 2001-06-22 | 2006-08-22 | Roche Diagnostics Corporation | Soluble complexes of amylod β peptide and peptidyl prolyl isomerase chaperone and methods of making and using them |
US6962982B2 (en) | 2001-06-22 | 2005-11-08 | Roche Diagnostics Corporation | Soluble complexes of target proteins and peptidyl prolyl isomerase chaperones and methods of making and using them |
ES2294196T3 (es) * | 2002-12-20 | 2008-04-01 | F. Hoffmann-La Roche Ag | Metodos para elaborar y utilizar complejos solubles de proteinas diana y chaperonas peptil prolil isomerasas. |
US9335331B2 (en) * | 2005-04-11 | 2016-05-10 | Cornell Research Foundation, Inc. | Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject |
JP4981305B2 (ja) * | 2005-11-11 | 2012-07-18 | 公益財団法人大阪バイオサイエンス研究所 | アルツハイマー病の発症リスク又はアルツハイマー病発症予後の予測方法 |
TW201214809A (en) * | 2010-01-29 | 2012-04-01 | Nitto Denko Corp | Light-emitting diode device |
US9522170B2 (en) | 2011-04-05 | 2016-12-20 | Alphabeta Ab | Methods of screening compounds for the fibril formation of Aβ peptides based on a decreased trimer/monomer ratio of a chaperone protein |
US20140302532A1 (en) | 2011-04-12 | 2014-10-09 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury |
WO2014012108A1 (en) * | 2012-07-13 | 2014-01-16 | Holtzman Jordan L | Cellular and animal models for screening therapeutic agents for the treatment of alzheimer's disease |
WO2018067854A1 (en) * | 2016-10-06 | 2018-04-12 | Ramp Research, Llc | Methods, compositions, and kits involving alteration of the chaperone protein axis in a subject |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223482A (en) | 1986-11-17 | 1993-06-29 | Scios Nova Inc. | Recombinant Alzheimer's protease inhibitory amyloid protein and method of use |
US5780587A (en) | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
ATE239797T1 (de) * | 1993-01-25 | 2003-05-15 | Takeda Chemical Industries Ltd | Antikörper gegen beta-amyloid oder derivative davon und seine verwendung |
US5707821A (en) | 1995-06-07 | 1998-01-13 | Athena Neurosciences, Inc. | Identification of phospholipase A2 inhibitors in Aβ peptide-mediated neurodegenerative disease |
JPH09178743A (ja) * | 1995-12-27 | 1997-07-11 | Oriental Yeast Co Ltd | 可溶性appの定量法 |
IL136306A (en) | 1997-12-10 | 2005-09-25 | Nps Pharma Inc | Bis (fluorophenyl) alkylamides and related compounds, pharmaceutical compositions comprising them and their use in treating neurological disease or disorder |
-
1999
- 1999-10-29 WO PCT/US1999/025593 patent/WO2000026251A2/en active IP Right Grant
- 1999-10-29 US US09/830,749 patent/US6972318B1/en not_active Expired - Lifetime
- 1999-10-29 IL IL14285299A patent/IL142852A0/xx unknown
- 1999-10-29 CA CA2348545A patent/CA2348545C/en not_active Expired - Fee Related
- 1999-10-29 EP EP99961552A patent/EP1125135B1/en not_active Expired - Lifetime
- 1999-10-29 AT AT99961552T patent/ATE284538T1/de not_active IP Right Cessation
- 1999-10-29 NZ NZ511589A patent/NZ511589A/en not_active IP Right Cessation
- 1999-10-29 AU AU18105/00A patent/AU764713B2/en not_active Ceased
- 1999-10-29 JP JP2000579637A patent/JP4571310B2/ja not_active Expired - Fee Related
- 1999-10-29 DE DE69922535T patent/DE69922535T2/de not_active Expired - Lifetime
- 1999-10-29 MX MXPA01004317A patent/MXPA01004317A/es active IP Right Grant
-
2001
- 2001-04-27 NO NO20012114A patent/NO331974B1/no not_active IP Right Cessation
- 2001-04-29 IL IL142852A patent/IL142852A/en not_active IP Right Cessation
-
2005
- 2005-09-19 US US11/231,065 patent/US7927824B2/en not_active Expired - Fee Related
-
2011
- 2011-04-19 US US13/089,940 patent/US8211658B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO331974B1 (no) | 2012-05-14 |
US8211658B2 (en) | 2012-07-03 |
JP4571310B2 (ja) | 2010-10-27 |
WO2000026251A9 (en) | 2001-01-04 |
CA2348545A1 (en) | 2000-05-11 |
AU764713B2 (en) | 2003-08-28 |
NZ511589A (en) | 2005-02-25 |
EP1125135B1 (en) | 2004-12-08 |
US20060024759A1 (en) | 2006-02-02 |
AU1810500A (en) | 2000-05-22 |
WO2000026251A2 (en) | 2000-05-11 |
DE69922535T2 (de) | 2005-05-12 |
NO20012114D0 (no) | 2001-04-27 |
IL142852A0 (en) | 2002-03-10 |
WO2000026251A3 (en) | 2000-08-10 |
CA2348545C (en) | 2012-08-21 |
EP1125135A2 (en) | 2001-08-22 |
MXPA01004317A (es) | 2003-06-06 |
ATE284538T1 (de) | 2004-12-15 |
US6972318B1 (en) | 2005-12-06 |
JP2002528555A (ja) | 2002-09-03 |
IL142852A (en) | 2010-05-31 |
US7927824B2 (en) | 2011-04-19 |
US20110256569A1 (en) | 2011-10-20 |
DE69922535D1 (de) | 2005-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Oka et al. | Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of Lens culinaris agglutinin‐reactive α‐fetoprotein 1 | |
Schwabl et al. | New reliability criteria for transient elastography increase the number of accurate measurements for screening of cirrhosis and portal hypertension | |
Sjogren et al. | Cytoskeleton proteins in CSF distinguish frontotemporal dementia from AD | |
Gervil et al. | The relative role of genetic and environmental factors in migraine without aura | |
NO20012114L (no) | Chaperonekompleks med <beta>-amyloid og anvendelse av komplekset | |
Margolis et al. | Huntington's disease–like 2 (HDL2) in North America and Japan | |
Olynyk et al. | Duration of hepatic iron exposure increases the risk of significant fibrosis in hereditary hemochromatosis: a new role for magnetic resonance imaging | |
GB0512401D0 (en) | Method | |
Gümüşay et al. | Diagnostic potential of serum direct markers and non‐invasive fibrosis models in patients with chronic hepatitis B | |
El-Mezayen et al. | Diagnostic performance of collagen IV and laminin for the prediction of fibrosis and cirrhosis in chronic hepatitis C patients: a multicenter study | |
ATE447713T1 (de) | S100-proteine und -autoantikörper als serummarker für krebs | |
Gürleyik et al. | Serum interleukin‐6 measurement in the diagnosis of acute appendicitis | |
Giannitrapani et al. | Nontumorous portal vein thrombosis in liver cirrhosis: possible role of β-blockers | |
Świderska et al. | Serum cytokeratin 18 M30 levels in chronic hepatitis B reflect both phase and histological activities of disease | |
Cheong et al. | A practical scoring system for predicting cirrhosis in patients with chronic viral hepatitis | |
Alboraie et al. | Egy-score predicts severe hepatic fibrosis and cirrhosis in Egyptians with chronic liver diseases: a pilot study | |
KR102591417B1 (ko) | 대변 모니터링 및 건강 지도 장치 | |
Kelly et al. | The relationship between acute ischaemic stroke and plasma D-dimer levels in patients developing neither venous thromboembolism nor major intercurrent illness | |
DK0514490T3 (da) | Allelisk forbindelse af human dopamin (D2) receptorgenet i kompulsionsforstyrrelser, såsom alkoholisme | |
Maskell et al. | A normal serum CRP measurement does not exclude deep vein thrombosis | |
Malcolm et al. | Carbohydrate-deficient transferrin and alcohol use in medical examiner cases | |
Hota et al. | Role of eosinophil count and neutrophil: lymphocyte count ratio as prognostic markers in patients with sepsis | |
JP2006300689A (ja) | 肝疾患病態判定用マーカー及び該マーカーを用いる肝疾患病態判定方法 | |
FI990380A0 (fi) | Diagnostinen ja seulontamenetelmä | |
DE68928106D1 (de) | Nachweis, quantifizierung und klassifizierung von ras-proteinen in körperflüssigkeiten und geweben |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ERR | Erratum |
Free format text: I PATENTTIDENDE NR. 22/07 BLE PATENTSOKNAD NR. 20012114 FEILAKTIG KUNNGJORT ENDELIG HENLAGT. SOKNADEN ER FORTSATT UNDER BEHANDLING Free format text: I PATENTTIDENDE NR. 22/07 BLE PATENTSOKNAD NR. 20012114 FEILAKTIG KUNNGJORT ENDELIG HENLAGT. SOKNADEN ER FORTSATT UNDER BEHANDLING. |
|
MM1K | Lapsed by not paying the annual fees |