NO20011089L - Fremgangsmåte for produksjon av sialylerte oligosakkarider - Google Patents
Fremgangsmåte for produksjon av sialylerte oligosakkariderInfo
- Publication number
- NO20011089L NO20011089L NO20011089A NO20011089A NO20011089L NO 20011089 L NO20011089 L NO 20011089L NO 20011089 A NO20011089 A NO 20011089A NO 20011089 A NO20011089 A NO 20011089A NO 20011089 L NO20011089 L NO 20011089L
- Authority
- NO
- Norway
- Prior art keywords
- oligosaccharide
- production
- sialic acid
- reducing sugar
- sialylated oligosaccharides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Beskrevet er fremgangsmåter for enzymatisk syntese av a-sialylerte oligosakkarid- glykosider. Spesifikt i de beskrevne fremgangsmåtene blir a2,3-sialyltransferase brukt for å overføre en analog av sialinsyre, anvendt som dets CMP-nukleotidderivat, til den ikke-reduserende sukkerterminalen av et oligosakkarid som har en fukosylgruppe i den nestsiste sakkaridenheten til den ikke-reduserende sukkerterminalen. Analogen av sialinsyre og oligosakkaridet anvendt i denne fremgangsmåten er selektert til å være kompatibel med sialyltransferasen som anvendes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/146,285 US6194178B1 (en) | 1998-09-03 | 1998-09-03 | Method for the production of sialylated oligosaccharides |
PCT/CA1999/000801 WO2000014264A1 (en) | 1998-09-03 | 1999-09-02 | Method for the production of sialylated oligosaccharides |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20011089D0 NO20011089D0 (no) | 2001-03-02 |
NO20011089L true NO20011089L (no) | 2001-04-30 |
Family
ID=22516665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20011089A NO20011089L (no) | 1998-09-03 | 2001-03-02 | Fremgangsmåte for produksjon av sialylerte oligosakkarider |
Country Status (8)
Country | Link |
---|---|
US (3) | US6194178B1 (no) |
EP (1) | EP1108054A1 (no) |
JP (1) | JP2002524084A (no) |
CN (1) | CN1317053A (no) |
AU (1) | AU5499899A (no) |
CA (1) | CA2337078A1 (no) |
NO (1) | NO20011089L (no) |
WO (1) | WO2000014264A1 (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6689604B1 (en) * | 1998-03-20 | 2004-02-10 | National Research Council Of Canada | Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses |
US6395282B1 (en) * | 1998-04-16 | 2002-05-28 | University Of Rochester | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules |
US6194178B1 (en) * | 1998-09-03 | 2001-02-27 | Synsorb Biotech Inc. | Method for the production of sialylated oligosaccharides |
US7090856B2 (en) * | 2003-06-19 | 2006-08-15 | Hong Kong University Of Science And Technology | Anti-fouling exopolysaccharides isolated from cultures of Vibrio alginolyticus and Vibrio proteolyticus |
US8507227B2 (en) * | 2006-03-09 | 2013-08-13 | Centre National De La Recherche Scientifique (Cnrs) | Method of producing sialylated oligosaccharides |
EP1911850A1 (en) * | 2006-10-09 | 2008-04-16 | Centre National De La Recherche Scientifique (Cnrs) | Method of producing 6-thio-sialylated glycoproteins and glycoconjugates |
WO2008151448A1 (en) * | 2007-06-15 | 2008-12-18 | National Research Council Of Canada | Engineered versions of polysialyltransferases with enhanced enzymatic properties |
EP2157870A1 (en) * | 2007-06-25 | 2010-03-03 | DSM IP Assets B.V. | Novel prebiotics |
GB0922066D0 (en) * | 2009-12-17 | 2010-02-03 | Univ Belfast | Modulator |
TWI563092B (en) * | 2012-08-20 | 2016-12-21 | Academia Sinica | Large scale enzymatic synthesis of oligosaccharides |
WO2014201462A1 (en) * | 2013-06-14 | 2014-12-18 | The Regents Of The University Of California | Automated carbohydrate synthesis |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US4727136A (en) | 1985-10-01 | 1988-02-23 | Canadian Patents And Development Ltd. | Modified meningococcal group B polysaccharide for conjugate vaccine |
US5079353A (en) | 1987-12-02 | 1992-01-07 | Chembiomed, Ltd. | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
DE4028800A1 (de) | 1990-09-11 | 1992-03-12 | Behringwerke Ag | Gentechnische sialylierung von glykoproteinen |
US5461143A (en) * | 1991-03-18 | 1995-10-24 | The Scripps Research Institute | Oligosaccharide enzyme substrates and inhibitors: methods and compositions |
US5374655A (en) | 1991-06-10 | 1994-12-20 | Alberta Research Council | Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures |
US5352670A (en) * | 1991-06-10 | 1994-10-04 | Alberta Research Council | Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides |
US5384249A (en) | 1991-12-17 | 1995-01-24 | Kyowa Hakko Kogyo Co., Ltd. | α2→3 sialyltransferase |
US5962294A (en) | 1992-03-09 | 1999-10-05 | The Regents Of The University Of California | Compositions and methods for the identification and synthesis of sialyltransferases |
DK0632831T3 (da) | 1992-03-09 | 2003-03-24 | Univ California | Nukleinsyre, ekspressionsvektor og sammensætninger til identificering og syntese af rekombinante sialyltransferaser |
US5728554A (en) | 1995-04-11 | 1998-03-17 | Cytel Corporation | Enzymatic synthesis of glycosidic linkages |
AUPN658795A0 (en) * | 1995-11-15 | 1995-12-07 | Commonwealth Scientific And Industrial Research Organisation | Method of producing alpha 2, 3 sialyltransferase |
US6194178B1 (en) * | 1998-09-03 | 2001-02-27 | Synsorb Biotech Inc. | Method for the production of sialylated oligosaccharides |
-
1998
- 1998-09-03 US US09/146,285 patent/US6194178B1/en not_active Expired - Fee Related
-
1999
- 1999-09-02 WO PCT/CA1999/000801 patent/WO2000014264A1/en not_active Application Discontinuation
- 1999-09-02 AU AU54998/99A patent/AU5499899A/en not_active Abandoned
- 1999-09-02 EP EP99941339A patent/EP1108054A1/en not_active Withdrawn
- 1999-09-02 CA CA002337078A patent/CA2337078A1/en not_active Abandoned
- 1999-09-02 JP JP2000569004A patent/JP2002524084A/ja not_active Withdrawn
- 1999-09-02 CN CN99810599A patent/CN1317053A/zh active Pending
- 1999-09-03 US US09/390,281 patent/US6528274B1/en not_active Expired - Fee Related
-
2001
- 2001-02-27 US US09/795,943 patent/US20010007760A1/en not_active Abandoned
- 2001-03-02 NO NO20011089A patent/NO20011089L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20010007760A1 (en) | 2001-07-12 |
EP1108054A1 (en) | 2001-06-20 |
US6194178B1 (en) | 2001-02-27 |
JP2002524084A (ja) | 2002-08-06 |
CA2337078A1 (en) | 2000-03-16 |
AU5499899A (en) | 2000-03-27 |
CN1317053A (zh) | 2001-10-10 |
US6528274B1 (en) | 2003-03-04 |
NO20011089D0 (no) | 2001-03-02 |
WO2000014264A1 (en) | 2000-03-16 |
WO2000014264A8 (en) | 2000-08-10 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |