NO20006566L - Fremgangsmåte for fastfasesyntesen av aldehyd, keton, oksim, amin, hydroksaminsyre og <alfa>,<beta>-umettede karboksylsyre og aldehydforbindelser - Google Patents

Fremgangsmåte for fastfasesyntesen av aldehyd, keton, oksim, amin, hydroksaminsyre og <alfa>,<beta>-umettede karboksylsyre og aldehydforbindelser

Info

Publication number
NO20006566L
NO20006566L NO20006566A NO20006566A NO20006566L NO 20006566 L NO20006566 L NO 20006566L NO 20006566 A NO20006566 A NO 20006566A NO 20006566 A NO20006566 A NO 20006566A NO 20006566 L NO20006566 L NO 20006566L
Authority
NO
Norway
Prior art keywords
aldehyde
oxime
ketone
beta
alpha
Prior art date
Application number
NO20006566A
Other languages
English (en)
Norwegian (no)
Other versions
NO20006566D0 (no
Inventor
Joseph M Salvino
George C Morton
Helen J Mason
Richard F Labaudiniere
Original Assignee
Aventis Pharm Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharm Prod Inc filed Critical Aventis Pharm Prod Inc
Publication of NO20006566D0 publication Critical patent/NO20006566D0/no
Publication of NO20006566L publication Critical patent/NO20006566L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/40—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of hydroxylamino or oxyimino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/42—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitrogen-to-nitrogen bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/66—Preparation of compounds containing amino groups bound to a carbon skeleton from or via metallo-organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
NO20006566A 1998-06-24 2000-12-21 Fremgangsmåte for fastfasesyntesen av aldehyd, keton, oksim, amin, hydroksaminsyre og <alfa>,<beta>-umettede karboksylsyre og aldehydforbindelser NO20006566L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/103,872 US6133409A (en) 1996-12-19 1998-06-24 Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
PCT/US1999/014251 WO1999067192A2 (en) 1998-06-24 1999-06-23 PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE, KETONE, OXIME, AMINE, HYDROXAMIC ACID AND α,β-UNSATURATED CARBOXYLIC ACID AND ALDEHYDE COMPOUNDS

Publications (2)

Publication Number Publication Date
NO20006566D0 NO20006566D0 (no) 2000-12-21
NO20006566L true NO20006566L (no) 2001-02-22

Family

ID=22297482

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006566A NO20006566L (no) 1998-06-24 2000-12-21 Fremgangsmåte for fastfasesyntesen av aldehyd, keton, oksim, amin, hydroksaminsyre og <alfa>,<beta>-umettede karboksylsyre og aldehydforbindelser

Country Status (19)

Country Link
US (1) US6133409A (de)
EP (3) EP1089958A4 (de)
JP (1) JP4070407B2 (de)
KR (1) KR100734157B1 (de)
CN (3) CN1307553A (de)
AP (1) AP2000001994A0 (de)
BG (1) BG65311B1 (de)
BR (1) BR9911499A (de)
CA (1) CA2335511A1 (de)
EA (1) EA004741B1 (de)
HK (1) HK1089193A1 (de)
HU (1) HUP0102856A3 (de)
IL (2) IL139796A0 (de)
NO (1) NO20006566L (de)
OA (1) OA11773A (de)
PL (1) PL199122B1 (de)
SK (1) SK20142000A3 (de)
UA (1) UA71917C2 (de)
WO (1) WO1999067192A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599753B1 (en) * 1998-06-24 2003-07-29 Aventis Pharmaceuticals Inc. Method and reagents for the quantification of solid-phase reactions using fluorine NMR
US6951958B1 (en) 1999-08-03 2005-10-04 Acadia Pharmaceuticals Inc. Solid phase parallel synthesis of tertiary amines
WO2002022622A2 (en) 2000-09-13 2002-03-21 Georgetown University Synthesis of 2-hydroxymethylglutamic acid and congeners thereof
AU9013101A (en) * 2000-09-29 2002-04-22 Prolifix Ltd Carbamic acid compounds comprising a sulfonamide linkage as hdac inhibitors
US20070021612A1 (en) * 2004-11-04 2007-01-25 University Of Notre Dame Du Lac Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof
US7235688B1 (en) 2004-11-04 2007-06-26 University Of Notre Dame Du Lac Process for preparing histone deacetylase inhibitors and intermediates thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507433A (en) * 1983-10-07 1985-03-26 The Johns Hopkins University Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates
US5783682A (en) * 1990-07-27 1998-07-21 Isis Pharmaceuticals, Inc. Oligonucleotide mimics having nitrogen-containing linkages
GB9503749D0 (en) * 1995-02-24 1995-04-12 British Biotech Pharm Synthesis of hydroxamic acid derivatives
PT871439E (pt) * 1996-01-02 2004-08-31 Aventis Pharma Inc Compostos do acido hidroxamico substituidos (arilo heteroarilo arilmetilo ou heteroarilmetilo)
DE69717117T2 (de) * 1996-08-05 2003-07-17 Prolinx Inc., Bothell Komplexreagenzien und komplexe, die eine borsäureverbindung enthalten
DE19635768A1 (de) * 1996-09-04 1998-03-05 Ernst Prof Dr Bayer Methacryloyl-Gruppen enthaltende polymere Trägersysteme, Verfahren zu ihrer Herstellung und ihre Verwendung in Festphasenreaktionen
AU5426398A (en) * 1996-10-28 1998-05-22 Versicor Inc Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
PL195867B1 (pl) * 1996-12-19 2007-11-30 Aventis Pharma Inc Sposób wytwarzania ketonów, aldehydów i sposób wytwarzania N-alkilowanej żywicy kwasu hydroksamowego
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
AU2495499A (en) * 1998-02-17 1999-08-30 Chembridge Corporation Supports for solid state chemical reactions and method of use thereof
KR100634035B1 (ko) * 1998-06-24 2006-10-17 아벤티스 파마슈티칼스 인크. 플루오로페닐 수지 화합물 및 이의 제조방법

Also Published As

Publication number Publication date
BG105166A (en) 2001-07-31
CN1307553A (zh) 2001-08-08
UA71917C2 (en) 2005-01-17
JP4070407B2 (ja) 2008-04-02
CN1769318A (zh) 2006-05-10
EA004741B1 (ru) 2004-08-26
PL345494A1 (en) 2001-12-17
US6133409A (en) 2000-10-17
IL139796A (en) 2009-05-04
CN1754899A (zh) 2006-04-05
SK20142000A3 (sk) 2001-07-10
EA200100072A1 (ru) 2001-06-25
EP1359136A3 (de) 2004-05-12
OA11773A (en) 2005-07-25
KR20010053169A (ko) 2001-06-25
BG65311B1 (bg) 2008-01-31
PL199122B1 (pl) 2008-08-29
EP1688406A3 (de) 2006-10-18
NO20006566D0 (no) 2000-12-21
EP1089958A4 (de) 2002-10-09
CA2335511A1 (en) 1999-12-29
BR9911499A (pt) 2006-01-03
AP2000001994A0 (en) 2000-12-31
HK1089193A1 (en) 2006-11-24
HUP0102856A2 (hu) 2001-11-28
EP1089958A2 (de) 2001-04-11
KR100734157B1 (ko) 2007-07-03
WO1999067192A2 (en) 1999-12-29
HUP0102856A3 (en) 2002-10-28
JP2002518553A (ja) 2002-06-25
WO1999067192A3 (en) 2000-04-06
IL139796A0 (en) 2002-02-10
EP1359136A2 (de) 2003-11-05
EP1688406A2 (de) 2006-08-09
CN100360580C (zh) 2008-01-09

Similar Documents

Publication Publication Date Title
DE60029042D1 (de) Festphase Nukleinsäuremarkierung durch Transaminierung
NO20093402L (no) Framgangsmate for syntetisering av camptothesin relaterte forbindelser
NO20014047L (no) Monoamin reopptaksinhibitorer for behandling av CNS forstyrrelser
HK1031399A1 (en) Process for synthesizing cox-2 inhibitors.
NO20013881D0 (no) Fremstilling av iodixanol
EP2039693A3 (de) Neuartige Synthese von Irbesartan
NO20006566L (no) Fremgangsmåte for fastfasesyntesen av aldehyd, keton, oksim, amin, hydroksaminsyre og &lt;alfa&gt;,&lt;beta&gt;-umettede karboksylsyre og aldehydforbindelser
HUP0000313A3 (en) Process for the solid phase synthesis of aldehydes ,ketones, oximes, amines and hidroxamic acid compounds
DE69910113D1 (de) Verfahren zur Herstellung von Stickstofftrifluorid durch Gas-Feststoffreaktion
ITMI991486A0 (it) Processo per la sintesi di citalopram
EG23247A (en) Process and plant for the heterogeneous synthesis of chemical compounds.
NO20005932D0 (no) Nye forbindelser avledet fra &lt;alfa&gt;-D-xylose, fremgangsmåte for fremstilling av slike og terapeutisk anvendelse
MXPA03002926A (es) Proceso para la sintesis de 2,2,6,6,-tetrametil-4--oxipiperidina.
FR2825086B1 (fr) Procede de fabrication d&#39;un ciment sulfo-alumineux et/ou ferro-alumineux, ciment obtenu par ce procede, et installation de mise en oeuvre
WO2000064882A3 (en) Enantiomers of mercapto lactones and processes for their synthesis
HUP0001613A2 (hu) Eljárás tercier nitrillel szubsztituált aromás vegyület előállítására
NO20014077L (no) Fremgangsmåte for krystallisering av N-(4-trifluormetylfenyl)- 5-metyl-isoksazol-4-karboksamid
HK1039611A1 (en) Method for the pressureless production of alpha, alpha-dimethylphenyl acetic acid from alpha, alpha-dimethyl benzyl cyanide
NO20031045L (no) Ny polymorf form av 17-&lt;beta&gt;-(N-tert.butylkarbamoyl)-4-aza-5- &lt;alfa&gt;-ANDROST-1-en-3-on og en fremgangsmåte for fremstilling av samme
FR2807040B1 (fr) Procede de preparation de composes 3-(4-hydroxy-1h-indol-5- ylmethyl)-pyridiniums utilisant une reaction d&#39;aldolisation
Pandita et al. An efficient procedure for microscale synthesis of semicarbazones
FR2801898B1 (fr) Procede de fabrication de liqueurs au lait et liqueurs au lait obtenues par la mise en oeuvre de ce procede
FR2788764B1 (fr) Procede de preparation d&#39;un compose de type indanone ou thioindanone
MD2170B1 (en) N-Vinylimidazoles and process for obtaining thereof
ZA991497B (en) Synthesis of epothilones, intermediates thereto and analogues thereof.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application