NO20005410L - Fremgangsmåte for fremstilling av metyl(2S)-2((3R)-3-(N-(tert- butyloksykarbamyl)-amino)-2-oksopyrrolidin-1-yl)propionat - Google Patents

Fremgangsmåte for fremstilling av metyl(2S)-2((3R)-3-(N-(tert- butyloksykarbamyl)-amino)-2-oksopyrrolidin-1-yl)propionat

Info

Publication number
NO20005410L
NO20005410L NO20005410A NO20005410A NO20005410L NO 20005410 L NO20005410 L NO 20005410L NO 20005410 A NO20005410 A NO 20005410A NO 20005410 A NO20005410 A NO 20005410A NO 20005410 L NO20005410 L NO 20005410L
Authority
NO
Norway
Prior art keywords
oxopyrrolidin
propionate
tert
amino
methyl
Prior art date
Application number
NO20005410A
Other languages
English (en)
Other versions
NO20005410D0 (no
Inventor
Richard John Brown
Craig Steven Harris
Chiu Wa Leung
Ian Patel
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20005410D0 publication Critical patent/NO20005410D0/no
Publication of NO20005410L publication Critical patent/NO20005410L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
NO20005410A 1998-04-29 2000-10-27 Fremgangsmåte for fremstilling av metyl(2S)-2((3R)-3-(N-(tert- butyloksykarbamyl)-amino)-2-oksopyrrolidin-1-yl)propionat NO20005410L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9809021.0A GB9809021D0 (en) 1998-04-29 1998-04-29 Chemical process
PCT/GB1999/001307 WO1999055669A1 (en) 1998-04-29 1999-04-27 Process for the preparation of methyl(2s)-2-[(3r)-3-(n-[tert-butyloxycarbonyl]-amino)-2-oxopyrrolidin-1-yl]propionate

Publications (2)

Publication Number Publication Date
NO20005410D0 NO20005410D0 (no) 2000-10-27
NO20005410L true NO20005410L (no) 2000-12-21

Family

ID=10831089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005410A NO20005410L (no) 1998-04-29 2000-10-27 Fremgangsmåte for fremstilling av metyl(2S)-2((3R)-3-(N-(tert- butyloksykarbamyl)-amino)-2-oksopyrrolidin-1-yl)propionat

Country Status (16)

Country Link
US (1) US6248903B1 (no)
EP (1) EP1076645B1 (no)
JP (1) JP2002513000A (no)
KR (1) KR20010043046A (no)
CN (1) CN1298387A (no)
AT (1) ATE260892T1 (no)
AU (1) AU3719199A (no)
BR (1) BR9910014A (no)
CA (1) CA2327363A1 (no)
DE (1) DE69915274T2 (no)
GB (1) GB9809021D0 (no)
IL (1) IL139310A0 (no)
NO (1) NO20005410L (no)
NZ (1) NZ506954A (no)
WO (1) WO1999055669A1 (no)
ZA (1) ZA200005302B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130285D0 (en) 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723534A (en) * 1971-05-28 1973-03-27 Monsanto Co Aryl methyl phenacyl sulfonium tetrafluoroborates
US4377515A (en) 1979-10-01 1983-03-22 Merck & Co., Inc. Long lasting agonists and antagonists of LH-RH
AU7604196A (en) 1995-10-30 1997-05-22 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
GB9702377D0 (en) 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives
AU727757B2 (en) * 1996-06-07 2000-12-21 Astrazeneca Ab Peptide derivatives
GB9624562D0 (en) 1996-11-27 1997-01-15 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
WO1999055669A1 (en) 1999-11-04
AU3719199A (en) 1999-11-16
NO20005410D0 (no) 2000-10-27
EP1076645A1 (en) 2001-02-21
KR20010043046A (ko) 2001-05-25
NZ506954A (en) 2003-06-30
US6248903B1 (en) 2001-06-19
IL139310A0 (en) 2001-11-25
ZA200005302B (en) 2001-10-01
CN1298387A (zh) 2001-06-06
CA2327363A1 (en) 1999-11-04
JP2002513000A (ja) 2002-05-08
ATE260892T1 (de) 2004-03-15
EP1076645B1 (en) 2004-03-03
BR9910014A (pt) 2001-01-09
DE69915274D1 (de) 2004-04-08
DE69915274T2 (de) 2005-02-24
GB9809021D0 (en) 1998-06-24

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