NO20005045L - Pulmonal og nasal tilföring av raloxifen - Google Patents

Pulmonal og nasal tilföring av raloxifen

Info

Publication number
NO20005045L
NO20005045L NO20005045A NO20005045A NO20005045L NO 20005045 L NO20005045 L NO 20005045L NO 20005045 A NO20005045 A NO 20005045A NO 20005045 A NO20005045 A NO 20005045A NO 20005045 L NO20005045 L NO 20005045L
Authority
NO
Norway
Prior art keywords
raloxifene
pulmonary
nasal administration
nasal
administration
Prior art date
Application number
NO20005045A
Other languages
English (en)
Other versions
NO20005045D0 (no
Inventor
Darrel Lavern Allen
Paula Ann Leiter
Richard Leon Tielking
Ronald Keith Wolff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20005045D0 publication Critical patent/NO20005045D0/no
Publication of NO20005045L publication Critical patent/NO20005045L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20005045A 1998-04-08 2000-10-06 Pulmonal og nasal tilföring av raloxifen NO20005045L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8110298P 1998-04-08 1998-04-08
PCT/US1999/007184 WO1999051096A1 (en) 1998-04-08 1999-03-31 Pulmonary and nasal delivery of raloxifene

Publications (2)

Publication Number Publication Date
NO20005045D0 NO20005045D0 (no) 2000-10-06
NO20005045L true NO20005045L (no) 2000-12-05

Family

ID=22162102

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005045A NO20005045L (no) 1998-04-08 2000-10-06 Pulmonal og nasal tilföring av raloxifen

Country Status (19)

Country Link
US (1) US6080762A (no)
EP (1) EP1067839A1 (no)
JP (1) JP2002510603A (no)
KR (1) KR20010042531A (no)
CN (1) CN1304290A (no)
AU (1) AU749751B2 (no)
BR (1) BR9909492A (no)
CA (1) CA2327670A1 (no)
EA (1) EA003328B1 (no)
HR (1) HRP20000666A2 (no)
HU (1) HUP0101737A3 (no)
ID (1) ID27606A (no)
IL (1) IL138687A0 (no)
NO (1) NO20005045L (no)
NZ (1) NZ507151A (no)
PL (1) PL343438A1 (no)
TR (1) TR200002855T2 (no)
WO (1) WO1999051096A1 (no)
ZA (1) ZA200005154B (no)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
JP4874483B2 (ja) 1999-06-09 2012-02-15 ロバート イー． シーバース 超臨界流体補助ネブライゼーション及びバブル乾燥
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
WO2001013891A2 (en) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
WO2001035946A2 (en) * 1999-11-15 2001-05-25 New Millennium Pharmaceutical Research, Inc. Intranasal administration of raloxifene and tamoxifen
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
JP2005501845A (ja) 2001-08-16 2005-01-20 メディカル リサーチ カウンシル キチン微小粒子およびそれらの医学的用途
WO2003043585A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
US20030215462A1 (en) * 2001-12-21 2003-11-20 Wacher Vincent J. Use of UGT inhibitors to increase bioavailability
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
US7677411B2 (en) * 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
SI1535349T1 (sl) * 2002-06-27 2014-10-30 Oriel Therapeutics, Inc. Naprave, sistemi in ustrezni postopki za predelavo, izdajo in/ali vrednotenje nefarmacevtskih suhih praškov
KR100779484B1 (ko) * 2002-10-04 2007-11-26 주식회사 만도 전자식유압브레이크의 마스터실린더
US7534348B2 (en) * 2003-09-12 2009-05-19 Fenwal, Inc. Flow-through removal device and system using such device
US7451761B2 (en) * 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
EP1786784B1 (en) 2004-08-20 2010-10-27 MannKind Corporation Catalysis of diketopiperazine synthesis
CA2578175C (en) 2004-08-23 2014-10-14 Mannkind Corporation Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
EA016072B1 (ru) * 2005-05-18 2012-01-30 Палметрикс Инк. Применение состава соли кальция для изменения биофизических свойств слизистой оболочки
US7803404B2 (en) 2005-09-14 2010-09-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
EP2570147B1 (en) 2008-06-13 2017-10-18 MannKind Corporation A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
WO2010033207A1 (en) 2008-09-19 2010-03-25 Nektar Therapeutics Polymer conjugates of therapeutic peptides
US20110171312A1 (en) * 2008-09-19 2011-07-14 Nektar Therapeutics Modified therapeutic peptides, methods of their preparation and use
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
PL2405963T3 (pl) 2009-03-11 2014-04-30 Mannkind Corp Urządzenie, układ i sposób pomiaru oporu inhalatora
EP2246050A1 (en) * 2009-04-27 2010-11-03 IMR - International Medical Research - Partner GmbH Combination therapy comprising mechanical vibration for the treatment of a disease of the musculoskeletal or nervous system
KR20180079458A (ko) 2009-06-12 2018-07-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105640925B (zh) 2010-08-30 2019-08-16 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
EP2448571B1 (en) 2010-08-30 2013-06-12 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
EP2621488B1 (en) 2010-09-29 2018-11-07 Pulmatrix Operating Company, Inc. Cationic dry powders
AU2011308865B2 (en) 2010-09-29 2017-01-05 Pulmatrix, Inc. Monovalent metal cation dry powders for inhalation
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
NZ629722A (en) 2012-02-29 2017-03-31 Pulmatrix Operating Co Inc Inhalable dry powders
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
CA2906817C (en) 2013-03-15 2022-01-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
CN105324106A (zh) 2013-04-01 2016-02-10 普马特里克斯营业公司 噻托铵干粉
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10653640B2 (en) 2016-10-11 2020-05-19 Gbs Global Biopharma, Inc. Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseases
JP7225104B2 (ja) 2017-02-01 2023-02-20 ジービーエス グローバル バイオファーマ，インコーポレイテッド マスト細胞関連炎症障害又は好塩基球媒介炎症障害の治療のためのカンナビノイド含有複合混合物
EP3630063A2 (en) 2017-05-22 2020-04-08 GBS Global Biopharma, Inc. Myrcene-containing complex mixtures targeting trpv1
WO2019226833A1 (en) 2018-05-22 2019-11-28 Gbs Global Biopharma, Inc. Cannabinoids and/or terpenes for use in trpv1 modulation
EP3990925A1 (en) 2019-06-28 2022-05-04 GBS Global Biopharma, Inc. Treatment of pain using allosteric modulator of trpv1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5441965A (en) * 1993-12-21 1995-08-15 Eli Lilly And Company Methods of inhibiting thrombin
US5478847A (en) * 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
US6399634B1 (en) * 1994-09-20 2002-06-04 Eli Lilly And Company Benzothiophene compounds, compositions, and methods
CA2214072C (en) * 1996-08-29 2006-11-14 Eli Lilly And Company Benzo [b] thiophene compounds, intermediates, processes, compositions, and methods

Also Published As

Publication number Publication date
US6080762A (en) 2000-06-27
ID27606A (id) 2001-04-12
AU3462599A (en) 1999-10-25
IL138687A0 (en) 2001-10-31
HUP0101737A2 (hu) 2002-05-29
AU749751B2 (en) 2002-07-04
CN1304290A (zh) 2001-07-18
ZA200005154B (en) 2002-06-10
NO20005045D0 (no) 2000-10-06
NZ507151A (en) 2002-11-26
KR20010042531A (ko) 2001-05-25
PL343438A1 (en) 2001-08-13
JP2002510603A (ja) 2002-04-09
CA2327670A1 (en) 1999-10-14
WO1999051096A1 (en) 1999-10-14
TR200002855T2 (tr) 2000-12-21
EP1067839A1 (en) 2001-01-17
BR9909492A (pt) 2000-12-12
EA003328B1 (ru) 2003-04-24
EA200001037A1 (ru) 2001-04-23
HUP0101737A3 (en) 2002-06-28
HRP20000666A2 (en) 2001-08-31

Similar Documents

Publication Publication Date Title
NO20005045L (no) Pulmonal og nasal tilföring av raloxifen
DK1233964T3 (da) Ny anvendelse og hidtil ukendte N-azabicycloamidderivater
IS5525A (is) Innúðabúnaður og aðferð
DK1454907T3 (da) Quninazolin og pyridopyrmidin-derivativer
DK1210943T3 (da) Ny anvendelse af budesonid og formoterol
FI974134A (fi) Verkkoelementtien hallinta
NO972983L (no) Sulfonamider og deres anvendelse
NO995784L (no) Fytosterol og/eller fytosterolderivater
DK1084102T3 (da) Nye 3-arylpropionsyrederivater og analoge
NO985344D0 (no) FremgangsmÕte og system for gjenvinning av glykol/saltholdige str°mmer
NO985936L (no) Nasal administrasjon av desmopressin
ID22320A (id) Struktur montasi sarung depan
NO996438D0 (no) Ny kombinasjon av astmamedikamenter
NO20013085D0 (no) Fosfororganiske forbindelser og deres anvendelse
NO20001718D0 (no) Benzen-fusjonerte heterocykliske derivater og anvendelse derav
ID22326A (id) Struktur montasi sarung garpu
NO984921D0 (no) Tienopyridinderivater og deres anvendelse
NO20016093L (no) Kloning og ekspresjon av en ny 5-HT4-receptor
PT1140994E (pt) Proteinas da superficie externa, suas genes e sua utilizacao
NO20001398D0 (no) Kombinasjon av en 5-HT1A antagonist og en selektiv h5-HT1B antagonist eller partial antagonist
DK1038882T4 (da) Termisk inhiberet stivelse og mel og fremgangsmåde til fremstilling deraf
NO20010786L (no) TPL-2/COT kinase og fremgangsmåter for anvendelse
NO990185L (no) FremgangsmÕte for fremstilling av naftypyridoner og mellomprodukter
SE9903009D0 (sv) Use of new responsive elements
SE9904269D0 (sv) Use of new responsive elements

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application