NO20004121D0 - New compounds and their use as positive AMPA receptor modulators - Google Patents
New compounds and their use as positive AMPA receptor modulatorsInfo
- Publication number
- NO20004121D0 NO20004121D0 NO20004121A NO20004121A NO20004121D0 NO 20004121 D0 NO20004121 D0 NO 20004121D0 NO 20004121 A NO20004121 A NO 20004121A NO 20004121 A NO20004121 A NO 20004121A NO 20004121 D0 NO20004121 D0 NO 20004121D0
- Authority
- NO
- Norway
- Prior art keywords
- new compounds
- receptor modulators
- ampa receptor
- positive ampa
- positive
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
- C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
- C07D285/28—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK22698 | 1998-02-18 | ||
PCT/DK1999/000070 WO1999042456A2 (en) | 1998-02-18 | 1999-02-18 | Novel compounds and their use as positive ampa receptor modulators |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004121D0 true NO20004121D0 (en) | 2000-08-17 |
NO20004121L NO20004121L (en) | 2000-10-17 |
Family
ID=8091151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004121A NO20004121L (en) | 1998-02-18 | 2000-08-17 | New compounds and their use as positive AMPA receptor modulators |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1071426A2 (en) |
JP (1) | JP2002504481A (en) |
CN (1) | CN1293665A (en) |
AU (1) | AU751384B2 (en) |
CA (1) | CA2320354A1 (en) |
EE (1) | EE200000468A (en) |
HU (1) | HUP0101280A3 (en) |
IL (1) | IL137720A0 (en) |
IS (1) | IS5581A (en) |
NO (1) | NO20004121L (en) |
NZ (1) | NZ506251A (en) |
PL (1) | PL342843A1 (en) |
RU (1) | RU2214405C2 (en) |
SK (1) | SK11892000A3 (en) |
TR (1) | TR200002427T2 (en) |
WO (1) | WO1999042456A2 (en) |
ZA (1) | ZA991301B (en) |
Families Citing this family (56)
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US7671200B2 (en) | 1999-10-27 | 2010-03-02 | Cytokinetics, Inc. | Quinazolinone KSP inhibitors |
DE10004572A1 (en) | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | New positive allosteric AMPA receptor modulators (PAARM), processes for their production and their use as medicines |
FR2812291B1 (en) * | 2000-07-28 | 2002-12-13 | Adir | NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
CN1314351A (en) * | 2001-03-22 | 2001-09-26 | 刘志红 | Process for synthesizing quinazolone and quinazolone compound with anti-cancer function |
TWI232863B (en) * | 2001-06-11 | 2005-05-21 | Akzo Nobel Nv | Benzoxazepine derivatives |
MXPA03011562A (en) | 2001-06-14 | 2004-03-18 | Akzo Nobel Nv | (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES AS POSITIVE MODULATORS OF THE AMPA RECEPTOR. |
CA2458388A1 (en) | 2001-10-10 | 2003-04-17 | Neurosearch A/S | Novel benzothiazine derivatives, their preparation and use |
AU2002352886B2 (en) | 2001-11-26 | 2008-10-16 | Cortex Pharmaceuticals, Inc. | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses |
FR2833955B1 (en) | 2001-12-21 | 2004-01-30 | Servier Lab | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2833950B1 (en) | 2001-12-21 | 2005-12-16 | Servier Lab | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
FR2833956B1 (en) * | 2001-12-21 | 2004-01-30 | Servier Lab | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2854634B1 (en) * | 2003-05-05 | 2005-07-08 | Servier Lab | NOVEL THIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2856065B1 (en) * | 2003-06-13 | 2005-08-19 | Servier Lab | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
FR2856064B1 (en) * | 2003-06-13 | 2005-08-19 | Servier Lab | NOVEL BENZOTHIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
EP1644369A2 (en) | 2003-07-02 | 2006-04-12 | F. Hoffmann-La Roche Ag | Arylamine-substituted quinazolinone compounds |
CA2536967A1 (en) | 2003-08-28 | 2005-03-17 | Nitromed, Inc. | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use |
US7244843B2 (en) | 2003-10-07 | 2007-07-17 | Bristol-Myers Squibb Company | Modulators of serotonin receptors |
FR2865474B1 (en) * | 2004-01-26 | 2008-06-13 | Servier Lab | NOVEL FLUORINATED BENZOTHIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
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PL2144506T3 (en) | 2007-01-03 | 2012-04-30 | Servier Lab | 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses |
CL2008000119A1 (en) | 2007-01-16 | 2008-05-16 | Wyeth Corp | COMPOUNDS DERIVED FROM PIRAZOL, ANTAGONISTS OF THE NICOTINIC ACETILCOLINE RECEIVER; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT OF DISEASES SUCH AS SENILE DEMENTIA, ALZHEIMER AND SCHIZOPHRENIA. |
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US8168632B2 (en) | 2007-08-10 | 2012-05-01 | Cortex Pharmaceuticals, Inc. | Bicyclic amide derivatives for the treatment of respiratory disorders |
US8263591B2 (en) | 2007-08-10 | 2012-09-11 | Cortex Pharmaceuticals, Inc. | Bicyclic amides for enhancing glutamatergic synaptic responses |
FR2933698A1 (en) | 2008-07-09 | 2010-01-15 | Servier Lab | NOVEL CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
FR2943342B1 (en) | 2009-03-20 | 2011-03-04 | Servier Lab | NOVEL BENZOTHIADIAZEPINES DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
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FR2955107B1 (en) * | 2010-01-08 | 2012-03-02 | Servier Lab | NOVEL THIOCHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
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CN102977054A (en) * | 2012-12-12 | 2013-03-20 | 中国药科大学 | Application of selective alpha2A receptor stimulant in treating alzheimer disease |
JO3316B1 (en) | 2013-05-30 | 2019-03-13 | Lilly Co Eli | 3,4-dihydroisoquinolin-2(1h)-yl compounds |
US9920010B2 (en) | 2013-05-30 | 2018-03-20 | Idorsia Pharmaceuticals Ltd | CXCR7 receptor modulators |
CN103275016B (en) * | 2013-06-04 | 2015-03-11 | 温州医科大学附属第二医院 | Synthetic method of 2-subsituted quinazoline compounds |
AU2014277952A1 (en) | 2013-06-13 | 2016-01-28 | Veroscience Llc | Compositions and methods for treating metabolic disorders |
CN103319381B (en) * | 2013-06-14 | 2014-08-27 | 湖州康企药业有限公司 | Preparation method of high-purity fine sulfanilamide |
CN103772296B (en) * | 2013-12-19 | 2015-06-17 | 安徽师范大学 | Synthesis method for quinazoline derivative |
EP3227263B1 (en) | 2014-12-01 | 2019-04-10 | Idorsia Pharmaceuticals Ltd | Cxcr7 receptor modulators |
CN105294599B (en) * | 2015-09-17 | 2017-09-22 | 三峡大学 | A kind of diazthines compound and its asymmetric synthetic method |
CN106946920A (en) * | 2017-04-05 | 2017-07-14 | 泰力特医药(湖北)有限公司 | A kind of preparation method of 4 amino phenyl boronic acid derivative |
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US5488049A (en) * | 1993-12-10 | 1996-01-30 | Fidia - Georgetown Institute For The Neuro-Sciences | Method of treating learning and memory disorders using benzothiadiazide derivatives as nootropic agents |
FR2722502B1 (en) * | 1994-07-12 | 1996-08-23 | Adir | NOVEL BENZOTHIADIAZINE DERIVATIVE, ITS PREPARATION METHOD AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
DE69739970D1 (en) * | 1996-01-29 | 2010-10-07 | Univ California | METHOD FOR TREATING SEXUAL MALFUNCTIONS |
WO1998012185A1 (en) * | 1996-09-17 | 1998-03-26 | The Regents Of The University Of California | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
-
1999
- 1999-02-18 IL IL13772099A patent/IL137720A0/en unknown
- 1999-02-18 NZ NZ506251A patent/NZ506251A/en unknown
- 1999-02-18 JP JP2000532408A patent/JP2002504481A/en not_active Withdrawn
- 1999-02-18 WO PCT/DK1999/000070 patent/WO1999042456A2/en not_active Application Discontinuation
- 1999-02-18 RU RU2000121882/04A patent/RU2214405C2/en not_active IP Right Cessation
- 1999-02-18 EP EP99904730A patent/EP1071426A2/en not_active Withdrawn
- 1999-02-18 CA CA002320354A patent/CA2320354A1/en not_active Abandoned
- 1999-02-18 TR TR2000/02427T patent/TR200002427T2/en unknown
- 1999-02-18 HU HU0101280A patent/HUP0101280A3/en unknown
- 1999-02-18 PL PL99342843A patent/PL342843A1/en unknown
- 1999-02-18 SK SK1189-2000A patent/SK11892000A3/en unknown
- 1999-02-18 ZA ZA9901301A patent/ZA991301B/en unknown
- 1999-02-18 EE EEP200000468A patent/EE200000468A/en unknown
- 1999-02-18 AU AU25123/99A patent/AU751384B2/en not_active Ceased
- 1999-02-18 CN CN99804196A patent/CN1293665A/en active Pending
-
2000
- 2000-08-04 IS IS5581A patent/IS5581A/en unknown
- 2000-08-17 NO NO20004121A patent/NO20004121L/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0101280A2 (en) | 2001-10-28 |
ZA991301B (en) | 1999-09-13 |
RU2214405C2 (en) | 2003-10-20 |
EE200000468A (en) | 2002-04-15 |
EP1071426A2 (en) | 2001-01-31 |
SK11892000A3 (en) | 2001-02-12 |
HUP0101280A3 (en) | 2003-02-28 |
CA2320354A1 (en) | 1999-08-26 |
NO20004121L (en) | 2000-10-17 |
WO1999042456A2 (en) | 1999-08-26 |
IL137720A0 (en) | 2001-10-31 |
JP2002504481A (en) | 2002-02-12 |
AU751384B2 (en) | 2002-08-15 |
WO1999042456A3 (en) | 1999-10-07 |
CN1293665A (en) | 2001-05-02 |
TR200002427T2 (en) | 2001-01-22 |
AU2512399A (en) | 1999-09-06 |
IS5581A (en) | 2000-08-04 |
NZ506251A (en) | 2003-01-31 |
PL342843A1 (en) | 2001-07-16 |
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