FR2877342B1 - NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - Google Patents

NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Info

Publication number
FR2877342B1
FR2877342B1 FR0411691A FR0411691A FR2877342B1 FR 2877342 B1 FR2877342 B1 FR 2877342B1 FR 0411691 A FR0411691 A FR 0411691A FR 0411691 A FR0411691 A FR 0411691A FR 2877342 B1 FR2877342 B1 FR 2877342B1
Authority
FR
France
Prior art keywords
preparing
pharmaceutical compositions
compositions containing
containing same
benzothiadiazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0411691A
Other languages
French (fr)
Other versions
FR2877342A1 (en
Inventor
Patrice Desos
Alexis Cordi
Pierre Lestage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to FR0411691A priority Critical patent/FR2877342B1/en
Priority to MA28555A priority patent/MA27918A1/en
Priority to SG200506774A priority patent/SG122000A1/en
Priority to EA200501529A priority patent/EA200501529A1/en
Priority to CA002524869A priority patent/CA2524869A1/en
Priority to ARP050104583A priority patent/AR051414A1/en
Priority to KR1020050104303A priority patent/KR20060052411A/en
Priority to GEAP20059037A priority patent/GEP20074217B/en
Priority to NO20055124A priority patent/NO20055124L/en
Priority to NZ543359A priority patent/NZ543359A/en
Priority to EP05292309A priority patent/EP1655299A1/en
Priority to US11/266,072 priority patent/US7262191B2/en
Priority to BRPI0505262-9A priority patent/BRPI0505262A/en
Priority to ZA200508928A priority patent/ZA200508928B/en
Priority to AU2005229699A priority patent/AU2005229699A1/en
Priority to MXPA05011819A priority patent/MXPA05011819A/en
Priority to CNA2005101249239A priority patent/CN1769276A/en
Priority to JP2005320479A priority patent/JP2006131634A/en
Publication of FR2877342A1 publication Critical patent/FR2877342A1/en
Application granted granted Critical
Publication of FR2877342B1 publication Critical patent/FR2877342B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • C07D285/181,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/201,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/221,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/241,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0411691A 2004-11-03 2004-11-03 NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Expired - Fee Related FR2877342B1 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR0411691A FR2877342B1 (en) 2004-11-03 2004-11-03 NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
MA28555A MA27918A1 (en) 2004-11-03 2005-10-17 NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
SG200506774A SG122000A1 (en) 2004-11-03 2005-10-17 New benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
EA200501529A EA200501529A1 (en) 2004-11-03 2005-10-28 NEW COMPOUNDS OF BENZOTHIADIAZINE, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
CA002524869A CA2524869A1 (en) 2004-11-03 2005-10-31 New benzothiadiazine derivatives, their preparation process and the pharmaceutical compounds that contain them
KR1020050104303A KR20060052411A (en) 2004-11-03 2005-11-02 New benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
GEAP20059037A GEP20074217B (en) 2004-11-03 2005-11-02 Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing
NO20055124A NO20055124L (en) 2004-11-03 2005-11-02 New Benzothiadiazine Compounds, Methods for their Preparation and Pharmaceutical Compositions Containing Them
NZ543359A NZ543359A (en) 2004-11-03 2005-11-02 Benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
EP05292309A EP1655299A1 (en) 2004-11-03 2005-11-02 Benzothiadiazine derivatives, process of preparation thereof and pharmaceutical compositions containing them
ARP050104583A AR051414A1 (en) 2004-11-03 2005-11-02 BENZOTIADIAZINE COMPOUNDS AS AMPA MODULATORS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM USED AS MEDICINES FOR THE TREATMENT OF NERVOUS SYSTEM DISEASES
BRPI0505262-9A BRPI0505262A (en) 2004-11-03 2005-11-03 benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing the same
ZA200508928A ZA200508928B (en) 2004-11-03 2005-11-03 Benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
US11/266,072 US7262191B2 (en) 2004-11-03 2005-11-03 Benzothiadiazine compounds
AU2005229699A AU2005229699A1 (en) 2004-11-03 2005-11-03 New benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
MXPA05011819A MXPA05011819A (en) 2004-11-03 2005-11-03 New benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them.
CNA2005101249239A CN1769276A (en) 2004-11-03 2005-11-03 Benzothiadiazine derivatives, process of preparation thereof and pharmaceutical compositions containing them
JP2005320479A JP2006131634A (en) 2004-11-03 2005-11-04 New benzothiadiazine compound, method for producing the same and medicinal composition containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0411691A FR2877342B1 (en) 2004-11-03 2004-11-03 NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Publications (2)

Publication Number Publication Date
FR2877342A1 FR2877342A1 (en) 2006-05-05
FR2877342B1 true FR2877342B1 (en) 2007-01-26

Family

ID=34950936

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0411691A Expired - Fee Related FR2877342B1 (en) 2004-11-03 2004-11-03 NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Country Status (18)

Country Link
US (1) US7262191B2 (en)
EP (1) EP1655299A1 (en)
JP (1) JP2006131634A (en)
KR (1) KR20060052411A (en)
CN (1) CN1769276A (en)
AR (1) AR051414A1 (en)
AU (1) AU2005229699A1 (en)
BR (1) BRPI0505262A (en)
CA (1) CA2524869A1 (en)
EA (1) EA200501529A1 (en)
FR (1) FR2877342B1 (en)
GE (1) GEP20074217B (en)
MA (1) MA27918A1 (en)
MX (1) MXPA05011819A (en)
NO (1) NO20055124L (en)
NZ (1) NZ543359A (en)
SG (1) SG122000A1 (en)
ZA (1) ZA200508928B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105294599B (en) * 2015-09-17 2017-09-22 三峡大学 A kind of diazthines compound and its asymmetric synthetic method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722502B1 (en) 1994-07-12 1996-08-23 Adir NOVEL BENZOTHIADIAZINE DERIVATIVE, ITS PREPARATION METHOD AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
CA2320354A1 (en) * 1998-02-18 1999-08-26 Neurosearch A/S Novel compounds and their use as positive ampa receptor modulators
FR2801587B1 (en) * 1999-11-30 2002-01-11 Adir NOVEL BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2833950B1 (en) * 2001-12-21 2005-12-16 Servier Lab NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2833956B1 (en) * 2001-12-21 2004-01-30 Servier Lab NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2833955B1 (en) * 2001-12-21 2004-01-30 Servier Lab NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
AR051414A1 (en) 2007-01-10
EP1655299A1 (en) 2006-05-10
JP2006131634A (en) 2006-05-25
NO20055124D0 (en) 2005-11-02
NO20055124L (en) 2006-05-04
CA2524869A1 (en) 2006-05-03
MA27918A1 (en) 2006-06-01
CN1769276A (en) 2006-05-10
US7262191B2 (en) 2007-08-28
BRPI0505262A (en) 2006-07-11
KR20060052411A (en) 2006-05-19
AU2005229699A1 (en) 2006-05-18
GEP20074217B (en) 2007-10-10
EA200501529A1 (en) 2006-06-30
FR2877342A1 (en) 2006-05-05
NZ543359A (en) 2007-04-27
US20060094713A1 (en) 2006-05-04
ZA200508928B (en) 2006-07-26
SG122000A1 (en) 2006-05-26
MXPA05011819A (en) 2006-05-08

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Legal Events

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ST Notification of lapse

Effective date: 20090731