NO20004098L - FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelser - Google Patents
FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelserInfo
- Publication number
- NO20004098L NO20004098L NO20004098A NO20004098A NO20004098L NO 20004098 L NO20004098 L NO 20004098L NO 20004098 A NO20004098 A NO 20004098A NO 20004098 A NO20004098 A NO 20004098A NO 20004098 L NO20004098 L NO 20004098L
- Authority
- NO
- Norway
- Prior art keywords
- macrophage
- preparations
- treatment
- methods
- mediated disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
- A61K47/6827—Ricin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5055—Cells of the immune system involving macrophages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physiology (AREA)
- Botany (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7496798P | 1998-02-17 | 1998-02-17 | |
PCT/US1999/003488 WO1999041285A1 (fr) | 1998-02-17 | 1999-02-17 | Traitement et diagnostic des maladies dues aux macrophages au moyen des ligands des recepteurs de fc |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004098D0 NO20004098D0 (no) | 2000-08-16 |
NO20004098L true NO20004098L (no) | 2000-10-02 |
Family
ID=22122724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004098A NO20004098L (no) | 1998-02-17 | 2000-08-16 | FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelser |
Country Status (15)
Country | Link |
---|---|
US (2) | US20020058284A1 (fr) |
EP (1) | EP1056781A1 (fr) |
JP (1) | JP2002503676A (fr) |
KR (1) | KR20010041010A (fr) |
CN (1) | CN1307590A (fr) |
AU (1) | AU2772199A (fr) |
CA (1) | CA2321136A1 (fr) |
EA (1) | EA200000848A1 (fr) |
HK (1) | HK1038931A1 (fr) |
HU (1) | HUP0100929A3 (fr) |
IL (1) | IL137919A0 (fr) |
NO (1) | NO20004098L (fr) |
PL (1) | PL342729A1 (fr) |
SI (1) | SI20475A (fr) |
WO (1) | WO1999041285A1 (fr) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6756396B1 (en) * | 1997-05-07 | 2004-06-29 | Qlt Inc. | Ethylene glycol esters as photoactive agents |
US7740854B2 (en) | 2001-05-02 | 2010-06-22 | Purdue Research Foundation | Treatment of macrophage mediated disease |
US8043602B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
US8968730B2 (en) | 2002-08-14 | 2015-03-03 | Macrogenics Inc. | FcγRIIB specific antibodies and methods of use thereof |
EP1534335B9 (fr) | 2002-08-14 | 2016-01-13 | Macrogenics, Inc. | Anticorps specifiques du recepteur fcgammariib et procedes d'utilisation de ces anticorps |
US8187593B2 (en) | 2002-08-14 | 2012-05-29 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
US8946387B2 (en) | 2002-08-14 | 2015-02-03 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
WO2007094776A1 (fr) * | 2006-02-15 | 2007-08-23 | William Marsh Rice University | Compositions et procédés de suppression de la différenciation des fibrocytes |
US8012472B2 (en) | 2002-12-23 | 2011-09-06 | William Marsh Rice University | Compositions and methods for suppressing fibrocytes |
US7763256B2 (en) * | 2002-12-23 | 2010-07-27 | William Marsh Rice University | Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation |
EP1576368B1 (fr) | 2002-12-23 | 2009-02-18 | William Marsh Rice Univeristy | Techniques et compositions permettant de renforcer la formation de fibroblastes |
US20100297074A1 (en) * | 2002-12-23 | 2010-11-25 | Richard Hans Gomer | Wound healing compositions, systems, and methods |
US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
AU2004204494B2 (en) | 2003-01-09 | 2011-09-29 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
EP1622646B1 (fr) * | 2003-05-06 | 2012-08-08 | Purdue Research Foundation | Traitement du lupus par ciblage des macrophages ou du recepteur de folate |
US20050008633A1 (en) * | 2003-05-19 | 2005-01-13 | Advanced Inhalation Research Inc. | Chemical and physical modulators of bioavailability of inhaled compositions |
BG65715B1 (bg) * | 2003-09-04 | 2009-08-31 | Чавдар ВАСИЛЕВ | Средство за селективно подтискане на патологични днк - специфични в клетки |
US7057624B2 (en) * | 2003-10-28 | 2006-06-06 | Eastman Kodak Company | Display device light leakage compensation |
EP1570858A1 (fr) * | 2004-03-05 | 2005-09-07 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Un ligand monovalent du recepteur FcalphaRI comme un agent anti-inflammatoire |
KR101297146B1 (ko) | 2004-05-10 | 2013-08-21 | 마크로제닉스, 인크. | 인간화 FcγRIIB 특이적 항체 및 그의 사용 방법 |
US20100166654A1 (en) * | 2004-12-03 | 2010-07-01 | The Uab Research Foundation | Single-Drug Multi-Ligand Conjugates for Targeted Drug Delivery |
US20060128031A1 (en) * | 2004-12-15 | 2006-06-15 | Robotti Karla M | Addressable recovery of bound analytes from an evanescent wave sensor |
EP1904183B1 (fr) | 2005-07-05 | 2014-10-15 | Purdue Research Foundation | Composition pharmaceutique pour le traitement de l'arthrose |
EP1940473A2 (fr) | 2005-09-23 | 2008-07-09 | Purdue Research Foundation | Procede et dispositif de cytometrie en flux in vivo |
CA2660592C (fr) | 2006-05-26 | 2016-07-12 | Macrogenics, Inc. | Anticorps specifiques fcgriib humanises, et leurs procedes d'utilisation |
CA2656224C (fr) | 2006-06-26 | 2018-01-09 | Macrogenics, Inc. | Association d'anticorps anti-fc.gamma.riib et d'anticorps anti-cd20, et methodes d'utilisation |
PL2029173T3 (pl) | 2006-06-26 | 2017-04-28 | Macrogenics, Inc. | Przeciwciała swoiste dla FC RIIB i sposoby ich zastosowania |
EP2087337A4 (fr) | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | Procédé de cytométrie en flux<i>ex vivo</i>et dispositif |
CA2708004C (fr) | 2006-12-04 | 2015-12-01 | Promedior, Inc. | Therapie conjointe pour le traitement de maladies fibrotiques |
WO2008140603A2 (fr) | 2006-12-08 | 2008-11-20 | Macrogenics, Inc. | MÉTHODES POUR LE TRAITEMENT DE MALADIE AU MOYEN D'IMMUNOGLOBULINES COMPRENANT DES RÉGIONS FC QUI PRÉSENTENT DES AFFINITÉS ALTÉRÉES POUR FCγR D'ACTIVATION ET FCγR D'INHIBITION |
WO2008098112A2 (fr) | 2007-02-07 | 2008-08-14 | Purdue Research Foundation | Procédé d'imagerie de tomographie par émission de positrons |
WO2008148001A2 (fr) | 2007-05-25 | 2008-12-04 | Purdue Research Foundation | Methode d'imagerie d'infections localisees |
US9884899B2 (en) * | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
US8497243B2 (en) | 2007-07-06 | 2013-07-30 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
CA2720365C (fr) | 2008-04-02 | 2019-01-15 | Macrogenics, Inc. | Anticorps specifiques du complexe bcr et procedes pour les utiliser |
DK2247304T3 (en) | 2008-04-02 | 2016-09-26 | Macrogenics Inc | Her2 / neu-specific antibodies and methods of use thereof |
PT2405929T (pt) * | 2009-03-11 | 2018-07-23 | Promedior Inc | Métodos de tratamento para distúrbios autoimunes |
ES2612922T3 (es) * | 2009-03-11 | 2017-05-19 | Promedior Inc. | Métodos de tratamiento y diagnóstico para trastornos de hipersensibilidad |
UA110323C2 (en) | 2009-06-04 | 2015-12-25 | Promedior Inc | Derivative of serum amyloid p and their receipt and application |
EP2987803B1 (fr) | 2009-06-17 | 2018-08-29 | Promedior Inc. | Variantes de sap et leurs utilisations |
WO2011017791A1 (fr) | 2009-08-10 | 2011-02-17 | Fundação Oswaldo Cruz | ANTICORPS MONOCLONAUX POUR LA PROTÉINE PBP2a ET SÉQUENCES HOMOLOGUES POUR LE TRAITEMENT D'INFECTIONS ET L'IMMUNODIAGNOSTIC DANS DES BACTÉRIES DU PHYLUM FIRMICUTES |
CA2776385C (fr) | 2009-10-07 | 2019-04-09 | Macrogenics, Inc. | Polypeptides contenant une region fc qui presentent une fonction d'effecteur amelioree due a des modifications de l'etendue de la fucosylation, et leurs methodes d'utilisation |
US8802091B2 (en) | 2010-03-04 | 2014-08-12 | Macrogenics, Inc. | Antibodies reactive with B7-H3 and uses thereof |
GEP20166442B (en) | 2010-03-04 | 2016-03-10 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
KR102006997B1 (ko) * | 2012-07-03 | 2019-08-02 | 한국생명공학연구원 | IgG Fc 위치선택적 결합 펩티드 및 이를 포함하는 하이브리드 분자 |
US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
TWI781098B (zh) | 2016-04-15 | 2022-10-21 | 美商宏觀基因股份有限公司 | 新穎的b7-h3-結合分子、其抗體藥物綴合物及其使用方法 |
CN109490540A (zh) * | 2017-09-13 | 2019-03-19 | 中国科学院上海药物研究所 | 单核/巨噬细胞在主动脉损伤中的诊断和治疗应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4671958A (en) * | 1982-03-09 | 1987-06-09 | Cytogen Corporation | Antibody conjugates for the delivery of compounds to target sites |
US4470925A (en) * | 1982-05-05 | 1984-09-11 | E. I. Du Pont De Nemours And Company | Immunoglobulin half-molecules and process for producing hybrid antibodies |
US4676980A (en) * | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
US4954617A (en) * | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
US5635600A (en) * | 1986-07-07 | 1997-06-03 | Trustees Of Dartmouth College | Bifunctional and heteroantibodies specific for the high affinity Fc receptor for immunoglobulin G on human mononuclear phagocytes |
US4869903A (en) * | 1987-05-29 | 1989-09-26 | Genelabs Incorporated | Method of selectively inhibiting HIV |
US5026557A (en) * | 1987-09-09 | 1991-06-25 | The Liposome Company, Inc. | Adjuvant composition |
US5840840A (en) * | 1990-04-17 | 1998-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Selective RNase cytotoxic reagents |
US5767106A (en) * | 1992-02-21 | 1998-06-16 | Hyal Pharmaceutical Corporation | Treatment of disease and conditions associated with macrophage infiltration |
US5686072A (en) * | 1992-06-17 | 1997-11-11 | Board Of Regents, The University Of Texas | Epitope-specific monoclonal antibodies and immunotoxins and uses thereof |
US5489525A (en) * | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
GB9223377D0 (en) * | 1992-11-04 | 1992-12-23 | Medarex Inc | Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes |
IL111105A (en) * | 1993-09-30 | 2009-05-04 | Univ Pennsylvania | Use of a molecule capable of inhibiting the expression of syk kinase to prepare a pharmaceutical composition for inhibiting phagocytosis |
US5578706A (en) * | 1993-11-04 | 1996-11-26 | Board Of Regents, The University Of Texas | Methods and compositions concerning homogenous immunotoxin preparations |
US5580715A (en) * | 1994-08-05 | 1996-12-03 | The Regents Of The University Of California | Diagnosis of cancer having clonal macrophage involvement |
US5922845A (en) * | 1996-07-11 | 1999-07-13 | Medarex, Inc. | Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies |
AU721792B2 (en) * | 1996-09-06 | 2000-07-13 | Medarex, Inc. | Cyanidin compositions and therapeutic and diagnostic uses therefor |
-
1999
- 1999-02-17 US US09/251,570 patent/US20020058284A1/en not_active Abandoned
- 1999-02-17 CA CA002321136A patent/CA2321136A1/fr not_active Abandoned
- 1999-02-17 EA EA200000848A patent/EA200000848A1/ru unknown
- 1999-02-17 IL IL13791999A patent/IL137919A0/xx unknown
- 1999-02-17 CN CN99805129A patent/CN1307590A/zh active Pending
- 1999-02-17 KR KR1020007009038A patent/KR20010041010A/ko not_active Application Discontinuation
- 1999-02-17 WO PCT/US1999/003488 patent/WO1999041285A1/fr not_active Application Discontinuation
- 1999-02-17 SI SI9920025A patent/SI20475A/sl not_active IP Right Cessation
- 1999-02-17 HU HU0100929A patent/HUP0100929A3/hu unknown
- 1999-02-17 EP EP99908236A patent/EP1056781A1/fr not_active Ceased
- 1999-02-17 AU AU27721/99A patent/AU2772199A/en not_active Abandoned
- 1999-02-17 PL PL99342729A patent/PL342729A1/xx not_active Application Discontinuation
- 1999-02-17 JP JP2000531476A patent/JP2002503676A/ja active Pending
-
2000
- 2000-08-16 NO NO20004098A patent/NO20004098L/no not_active Application Discontinuation
-
2002
- 2002-01-25 HK HK02100608.2A patent/HK1038931A1/zh unknown
-
2003
- 2003-07-25 US US10/627,307 patent/US20040141967A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NO20004098D0 (no) | 2000-08-16 |
KR20010041010A (ko) | 2001-05-15 |
CA2321136A1 (fr) | 1999-08-19 |
CN1307590A (zh) | 2001-08-08 |
JP2002503676A (ja) | 2002-02-05 |
SI20475A (sl) | 2001-08-31 |
US20020058284A1 (en) | 2002-05-16 |
HUP0100929A3 (en) | 2005-10-28 |
EA200000848A1 (ru) | 2001-04-23 |
HK1038931A1 (zh) | 2002-04-04 |
HUP0100929A2 (hu) | 2001-06-28 |
WO1999041285A1 (fr) | 1999-08-19 |
EP1056781A1 (fr) | 2000-12-06 |
AU2772199A (en) | 1999-08-30 |
PL342729A1 (en) | 2001-07-02 |
IL137919A0 (en) | 2001-10-31 |
US20040141967A1 (en) | 2004-07-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20004098L (no) | FremgangsmÕter og preparater for behandling av makrofag- formidlede lidelser | |
NO972972D0 (no) | Sammensetninger for behandling av dermatologiske forstyrrelser og metoder for deres anvendelse | |
NO994613D0 (no) | Fremgangsmaate og preparat til behandling av sövn-apne | |
NO20001754L (no) | Prostaglandinagonister og anvendelse derav for behandling av benforstyrrelser | |
NO971015D0 (no) | Forbindelser og metoder for behandling av cancer | |
NO994778D0 (no) | FremgangsmÕter og sammensetninger for behandling av tarmbetennelse | |
NO996483D0 (no) | Imidazopyrimidiner og imidazopyridiner for behandling av neurologiske forstyrrelser | |
IS5500A (is) | Lyfjablöndur til öftrunar og meðferðar mýlildi ogtengdum sjúkdómum | |
NO994014L (no) | Arylsulfonamider og analoger derav og deres anvendelse for behandling av neurodegenerative sykdommer | |
DE60023128D1 (de) | Pyrazolecarboxamide zur behandlung von fettleibigkeit und anderen erkrankungen | |
DE69825447D1 (de) | Gerät zur dermatologischen behandlung | |
HUP9904361A3 (en) | Use of isobutylgaba and its derivatives for the treatment of pain | |
NO985484D0 (no) | FremgangsmÕte og preparat for behandling og forhindring av hyperurikemi | |
NO20015542D0 (no) | Fremgangsmåte for fremstilling og anvendelse av N- desmetylzopikloner | |
NO20012963D0 (no) | Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler | |
NO20001412D0 (no) | Sammensetninger og fremgangsmåter ved behandling av respiratoriske forstyrrelser | |
NO20003229L (no) | Kombinasjon av benzosykloheptapyridinforbindelser og antineoplastiske midler for behandling av proliferaktive sykdommer | |
NO983512D0 (no) | Midler for behandling og forhindring av AIDS | |
EP1030663A4 (fr) | Traitement de fibromyalgie et de troubles qui y sont lies | |
DE69825319D1 (de) | Präparat zur vorbeugung und behandlung von entzündungen | |
PT932400E (pt) | Derivados de anticonvulsionantes uteis no tratamento da dor neuropatica | |
NO20010464L (no) | FremgangsmÕter og preparater for behandling av gastro- øsofagealt-reflukssyndrom | |
NO20001758D0 (no) | Fremgangsmåter og blandinger for behandling av leddgikt | |
NO973193D0 (no) | Kollagen-baserte metoder og formuleringer for behandling av immune system-medierte sykdommer | |
HUP0000785A3 (en) | Ointment for the treatment of burns and other skin diseases |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |