NO20002013L - Suspension packaging cell lines for retroviral vectors - Google Patents

Suspension packaging cell lines for retroviral vectors

Info

Publication number
NO20002013L
NO20002013L NO20002013A NO20002013A NO20002013L NO 20002013 L NO20002013 L NO 20002013L NO 20002013 A NO20002013 A NO 20002013A NO 20002013 A NO20002013 A NO 20002013A NO 20002013 L NO20002013 L NO 20002013L
Authority
NO
Norway
Prior art keywords
cell lines
packaging cell
retroviral vectors
suspension
suspension packaging
Prior art date
Application number
NO20002013A
Other languages
Norwegian (no)
Other versions
NO20002013D0 (en
Inventor
Stefan Seeber
Stefan Koch
Thorsten Gutjahr
Ulrich Steegmans
Ruediger Rueger
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of NO20002013D0 publication Critical patent/NO20002013D0/en
Publication of NO20002013L publication Critical patent/NO20002013L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13051—Methods of production or purification of viral material
    • C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Det beskrives en forpakningscellelinje som fullstendig vokser i suspensjon, og som er transfektert med et retrovirusvektorplasmid eller transdusert med en retrovirus- vektor, samt fremgangsmåter for fremstilling av slike cellelinjer fra suspensjons- cellelinjer eller adherent voksende cellelinjer.There is disclosed a packaging cell line which completely grows in suspension, which is transfected with a retroviral vector plasmid or transduced with a retroviral vector, and methods for producing such cell lines from suspension cell lines or adherent growing cell lines.

NO20002013A 1997-10-25 2000-04-17 Suspension packaging cell lines for retroviral vectors NO20002013L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97118583 1997-10-25
EP97121724 1997-12-10
PCT/EP1998/006714 WO1999021967A1 (en) 1997-10-25 1998-10-22 Suspension packing cell lines for retrovirus vectors

Publications (2)

Publication Number Publication Date
NO20002013D0 NO20002013D0 (en) 2000-04-17
NO20002013L true NO20002013L (en) 2000-04-17

Family

ID=26145852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002013A NO20002013L (en) 1997-10-25 2000-04-17 Suspension packaging cell lines for retroviral vectors

Country Status (16)

Country Link
EP (1) EP1025207B1 (en)
JP (1) JP3517399B2 (en)
KR (1) KR100359542B1 (en)
CN (1) CN1277631A (en)
AT (1) ATE304048T1 (en)
AU (1) AU729986B2 (en)
BR (1) BR9812960A (en)
CA (1) CA2306634C (en)
DE (1) DE59813048D1 (en)
ES (1) ES2248920T3 (en)
HU (1) HUP0004240A2 (en)
IL (1) IL135541A (en)
NO (1) NO20002013L (en)
NZ (1) NZ503827A (en)
TR (1) TR200001125T2 (en)
WO (1) WO1999021967A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100507794B1 (en) * 2003-02-11 2005-08-17 한미약품 주식회사 Method for preparing concentrated retroviral particle dispersion
EP1739180A1 (en) * 2005-06-27 2007-01-03 Max-Delbrück-Centrum für Molekulare Medizin (MDC) T cell line-based packaging cell line for the production of retroviruses by enriching of CD3 expressing cells
DK3159415T3 (en) 2009-06-17 2019-04-23 Tocagen Inc Production cells for replicative retroviral vectors
CN111286517A (en) * 2018-12-07 2020-06-16 珠海联邦制药股份有限公司 Packaging method of replication-defective retrovirus and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4059485A (en) * 1976-11-03 1977-11-22 Monsanto Company Adaptation of cell lines to suspension culture
RU1347448C (en) * 1985-09-27 1995-04-10 Институт полиомиелита и вирусных энцефалитов Российской АМН Strain taurus-1 of heteroploid cells of calf kidney used for virus cultivation
CA2001815C (en) * 1988-10-31 2002-09-03 Wen-Hwa Lee Products and methods for controlling the suppression of the neoplastic phenotype
DE19612966B4 (en) * 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK cells and methods of propagating influenza viruses

Also Published As

Publication number Publication date
JP2001520879A (en) 2001-11-06
CA2306634A1 (en) 1999-05-06
JP3517399B2 (en) 2004-04-12
NO20002013D0 (en) 2000-04-17
TR200001125T2 (en) 2000-09-21
DE59813048D1 (en) 2005-10-13
CN1277631A (en) 2000-12-20
KR100359542B1 (en) 2002-10-31
CA2306634C (en) 2005-04-12
BR9812960A (en) 2000-08-08
AU729986B2 (en) 2001-02-22
EP1025207A1 (en) 2000-08-09
EP1025207B1 (en) 2005-09-07
IL135541A0 (en) 2001-05-20
IL135541A (en) 2004-02-19
HUP0004240A2 (en) 2001-03-28
NZ503827A (en) 2001-06-29
AU1231399A (en) 1999-05-17
ES2248920T3 (en) 2006-03-16
WO1999021967A1 (en) 1999-05-06
ATE304048T1 (en) 2005-09-15
KR20010031387A (en) 2001-04-16

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application