IL135541A0 - Suspension packing cell lines for retrovirus vectors - Google Patents

Suspension packing cell lines for retrovirus vectors

Info

Publication number
IL135541A0
IL135541A0 IL13554198A IL13554198A IL135541A0 IL 135541 A0 IL135541 A0 IL 135541A0 IL 13554198 A IL13554198 A IL 13554198A IL 13554198 A IL13554198 A IL 13554198A IL 135541 A0 IL135541 A0 IL 135541A0
Authority
IL
Israel
Prior art keywords
cell lines
retrovirus vectors
packing cell
suspension
suspension packing
Prior art date
Application number
IL13554198A
Other versions
IL135541A (en
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of IL135541A0 publication Critical patent/IL135541A0/en
Publication of IL135541A publication Critical patent/IL135541A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13051—Methods of production or purification of viral material
    • C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a packing cell line fully growing in a suspension, which is transfected with a retrovirus plasmid or transduced with a retrovirus vector. The invention aslo relates to a method for the production of said cell lines from suspension cell lines or adheringly growing cell lines.
IL13554198A 1997-10-25 1998-10-22 Process for the production of suspension packing cell lines for retrovirus vectors IL135541A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97118583 1997-10-25
EP97121724 1997-12-10
PCT/EP1998/006714 WO1999021967A1 (en) 1997-10-25 1998-10-22 Suspension packing cell lines for retrovirus vectors

Publications (2)

Publication Number Publication Date
IL135541A0 true IL135541A0 (en) 2001-05-20
IL135541A IL135541A (en) 2004-02-19

Family

ID=26145852

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13554198A IL135541A (en) 1997-10-25 1998-10-22 Process for the production of suspension packing cell lines for retrovirus vectors

Country Status (16)

Country Link
EP (1) EP1025207B1 (en)
JP (1) JP3517399B2 (en)
KR (1) KR100359542B1 (en)
CN (1) CN1277631A (en)
AT (1) ATE304048T1 (en)
AU (1) AU729986B2 (en)
BR (1) BR9812960A (en)
CA (1) CA2306634C (en)
DE (1) DE59813048D1 (en)
ES (1) ES2248920T3 (en)
HU (1) HUP0004240A2 (en)
IL (1) IL135541A (en)
NO (1) NO20002013L (en)
NZ (1) NZ503827A (en)
TR (1) TR200001125T2 (en)
WO (1) WO1999021967A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100507794B1 (en) * 2003-02-11 2005-08-17 한미약품 주식회사 Method for preparing concentrated retroviral particle dispersion
EP1739180A1 (en) * 2005-06-27 2007-01-03 Max-Delbrück-Centrum für Molekulare Medizin (MDC) T cell line-based packaging cell line for the production of retroviruses by enriching of CD3 expressing cells
US10316333B2 (en) 2009-06-17 2019-06-11 Tocagen Inc. Producer cells for replication competent retroviral vectors
CN111286517A (en) * 2018-12-07 2020-06-16 珠海联邦制药股份有限公司 Packaging method of replication-defective retrovirus and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4059485A (en) * 1976-11-03 1977-11-22 Monsanto Company Adaptation of cell lines to suspension culture
RU1347448C (en) * 1985-09-27 1995-04-10 Институт полиомиелита и вирусных энцефалитов Российской АМН Strain taurus-1 of heteroploid cells of calf kidney used for virus cultivation
EP0440744B1 (en) * 1988-10-31 1997-12-10 The Regents Of The University Of California Products and methods for controlling the suppression of the neoplastic phenotype
DE19612966B4 (en) * 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK cells and methods of propagating influenza viruses

Also Published As

Publication number Publication date
WO1999021967A1 (en) 1999-05-06
IL135541A (en) 2004-02-19
KR100359542B1 (en) 2002-10-31
NO20002013D0 (en) 2000-04-17
KR20010031387A (en) 2001-04-16
TR200001125T2 (en) 2000-09-21
NZ503827A (en) 2001-06-29
JP2001520879A (en) 2001-11-06
AU729986B2 (en) 2001-02-22
EP1025207B1 (en) 2005-09-07
HUP0004240A2 (en) 2001-03-28
JP3517399B2 (en) 2004-04-12
EP1025207A1 (en) 2000-08-09
CN1277631A (en) 2000-12-20
CA2306634C (en) 2005-04-12
ATE304048T1 (en) 2005-09-15
BR9812960A (en) 2000-08-08
CA2306634A1 (en) 1999-05-06
NO20002013L (en) 2000-04-17
ES2248920T3 (en) 2006-03-16
DE59813048D1 (en) 2005-10-13
AU1231399A (en) 1999-05-17

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees