NO20002006L - Nye metylenbisfosfonsyrederivater - Google Patents

Nye metylenbisfosfonsyrederivater

Info

Publication number
NO20002006L
NO20002006L NO20002006A NO20002006A NO20002006L NO 20002006 L NO20002006 L NO 20002006L NO 20002006 A NO20002006 A NO 20002006A NO 20002006 A NO20002006 A NO 20002006A NO 20002006 L NO20002006 L NO 20002006L
Authority
NO
Norway
Prior art keywords
acid derivatives
bisphosphonic acid
new methylene
methylene bisphosphonic
new
Prior art date
Application number
NO20002006A
Other languages
English (en)
Norwegian (no)
Other versions
NO20002006D0 (no
Inventor
Esko Pohjala
Jouko Vepsoloinen
Heikki Nupponen
Jouni Kohkoenen
Leena Lauren
Ritva Hannuniemi
Tomi Jorvinen
Marko Ahlmark
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of NO20002006D0 publication Critical patent/NO20002006D0/no
Publication of NO20002006L publication Critical patent/NO20002006L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/409—Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/409—Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
    • C07F9/4093—Compounds containing the structure P(=X)-X-C(=X)- (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20002006A 1997-10-20 2000-04-17 Nye metylenbisfosfonsyrederivater NO20002006L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI974001A FI104901B (sv) 1997-10-20 1997-10-20 Nya metylenbisfosfonsyraderivat
PCT/FI1998/000814 WO1999020634A1 (en) 1997-10-20 1998-10-20 Novel methylenebisphosphonic acid derivatives

Publications (2)

Publication Number Publication Date
NO20002006D0 NO20002006D0 (no) 2000-04-17
NO20002006L true NO20002006L (no) 2000-06-15

Family

ID=8549759

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002006A NO20002006L (no) 1997-10-20 2000-04-17 Nye metylenbisfosfonsyrederivater

Country Status (19)

Country Link
US (1) US6326363B1 (sv)
EP (1) EP1032578A1 (sv)
JP (1) JP2001520232A (sv)
KR (1) KR20010031269A (sv)
CN (1) CN1147497C (sv)
AU (1) AU740355B2 (sv)
BG (1) BG104452A (sv)
BR (1) BR9813102A (sv)
CA (1) CA2306080A1 (sv)
EE (1) EE04061B1 (sv)
FI (1) FI104901B (sv)
HU (1) HUP0004386A3 (sv)
IL (1) IL135639A0 (sv)
NO (1) NO20002006L (sv)
NZ (1) NZ504390A (sv)
PL (1) PL340055A1 (sv)
RU (1) RU2205833C2 (sv)
TR (1) TR200001055T2 (sv)
WO (1) WO1999020634A1 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
WO2008024169A1 (en) * 2006-07-21 2008-02-28 Glsynthesis, Inc. Reactive pyrophosphoric and bisphosphonic acid derivatives and methods of their use
EP2364086B1 (en) 2008-11-20 2016-09-14 Glsynthesis Inc. Novel antithrombotic diadenosine tetraphosphates and related analogs
CN107011380A (zh) * 2016-01-28 2017-08-04 臧伟 一种二膦酸衍生物及含二膦酸衍生物的组合物治疗骨折的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447256A (en) 1977-07-20 1984-05-08 Nissan Chemical Industries, Ltd. N-(Unsubstituted or substituted pyridyl)aminomethylene-diphosphonic acids, herbicidal compositions containing same, their use for herbicides, and process for preparing same
DE2758580A1 (de) 1977-12-29 1979-07-05 Hoechst Ag Verfahren zur herstellung von phosphin- und phosphonsaeure-anhydriden
DK126888A (da) 1987-03-10 1988-09-11 Yamanouchi Pharma Co Ltd Bisphosphonsyrederivater og terapeutiske praeparater indeholdende disse forbindelser
US4933472A (en) 1988-04-08 1990-06-12 Yamanouchi Pharmaceutical Co., Ltd. Substituted aminomethylenebis(phosphonic acid) derivatives
EP0356866A3 (en) 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphorus-containing squalene synthetase inhibitors and method
FI83421C (sv) * 1989-06-21 1991-07-10 Huhtamaeki Oy Förfarande för framställning av farmakologiskt användbara metylenbisfo sfonsyraderivat
EP0416689B1 (en) 1989-09-06 1995-11-29 Merck & Co. Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
FI89364C (sv) * 1990-12-20 1993-09-27 Leiras Oy Förfarande för framställning av nya, farmakologiskt användbara metylen bisfosfonsyraderivat
FI89365C (sv) * 1990-12-20 1993-09-27 Leiras Oy Förfarande för framställning av nya farmakologiskt användbara metylenb isfosfonsyraderivat
FI89366C (sv) 1990-12-20 1993-09-27 Leiras Oy Förfarande för framställning av nya farmakologiskt användbara metylenb isfosfonsyraderivat
ATE127808T1 (de) 1991-04-06 1995-09-15 Fisons Plc Atp-analogen.
TW237386B (sv) 1992-04-15 1995-01-01 Ciba Geigy
DK0683789T3 (da) * 1993-02-10 1998-02-09 Astra Pharma Prod N-alkyl-2-substituerede ATP-analoger
US5462932A (en) 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations

Also Published As

Publication number Publication date
FI974001A0 (fi) 1997-10-20
WO1999020634A1 (en) 1999-04-29
NZ504390A (en) 2001-10-26
RU2205833C2 (ru) 2003-06-10
PL340055A1 (en) 2001-01-15
IL135639A0 (en) 2001-05-20
AU740355B2 (en) 2001-11-01
HUP0004386A3 (en) 2002-08-28
JP2001520232A (ja) 2001-10-30
US6326363B1 (en) 2001-12-04
EE04061B1 (et) 2003-06-16
CN1147497C (zh) 2004-04-28
CA2306080A1 (en) 1999-04-29
KR20010031269A (ko) 2001-04-16
EP1032578A1 (en) 2000-09-06
AU9543798A (en) 1999-05-10
BR9813102A (pt) 2000-08-22
BG104452A (en) 2000-12-29
EE200000239A (et) 2001-08-15
FI974001A (sv) 1999-04-21
CN1276793A (zh) 2000-12-13
NO20002006D0 (no) 2000-04-17
FI104901B (sv) 2000-04-28
TR200001055T2 (tr) 2000-09-21
HUP0004386A2 (hu) 2001-04-28

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application