NO20000863D0 - Arylpyridazinones as biosynthesis inhibitors of prostaglandin endoperoxidase H synthase - Google Patents
Arylpyridazinones as biosynthesis inhibitors of prostaglandin endoperoxidase H synthaseInfo
- Publication number
- NO20000863D0 NO20000863D0 NO20000863A NO20000863A NO20000863D0 NO 20000863 D0 NO20000863 D0 NO 20000863D0 NO 20000863 A NO20000863 A NO 20000863A NO 20000863 A NO20000863 A NO 20000863A NO 20000863 D0 NO20000863 D0 NO 20000863D0
- Authority
- NO
- Norway
- Prior art keywords
- arylpyridazinones
- synthase
- biosynthesis inhibitors
- prostaglandin endoperoxidase
- endoperoxidase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91702397A | 1997-08-22 | 1997-08-22 | |
US12957098A | 1998-08-05 | 1998-08-05 | |
PCT/US1998/016479 WO1999010331A1 (en) | 1997-08-22 | 1998-08-10 | Arylpyridazinones as prostaglandin endoperoxide h synthase biosynthesis inhibitors |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20000863L NO20000863L (en) | 2000-02-22 |
NO20000863D0 true NO20000863D0 (en) | 2000-02-22 |
NO315423B1 NO315423B1 (en) | 2003-09-01 |
Family
ID=26827711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20000863A NO315423B1 (en) | 1997-08-22 | 2000-02-22 | Arylpyridazinones as biosynthesis inhibitors of prostaglandin endoperoxidase H synthase, their preparation and pharmaceutical composition comprising the same |
Country Status (14)
Country | Link |
---|---|
JP (1) | JP2003516925A (en) |
KR (1) | KR100675028B1 (en) |
CN (1) | CN1167687C (en) |
AR (1) | AR015422A1 (en) |
AU (1) | AU741317B2 (en) |
BG (1) | BG64675B1 (en) |
CZ (1) | CZ300847B6 (en) |
HU (1) | HUP0400909A3 (en) |
IL (1) | IL133552A (en) |
NO (1) | NO315423B1 (en) |
NZ (1) | NZ501808A (en) |
PL (1) | PL194175B1 (en) |
SK (1) | SK286972B6 (en) |
TR (1) | TR200000478T2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR200101765T2 (en) * | 1998-10-27 | 2002-02-21 | Abbott Laboratories | Prostaglandin endoperoxide H synthase biosynthesis inhibitors |
FR2969606B1 (en) * | 2010-12-22 | 2013-01-11 | Pf Medicament | DERIVATIVES OF DIARYLPYRIDAZINONES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS |
CN107334767B (en) * | 2017-06-08 | 2019-03-05 | 中国医学科学院医药生物技术研究所 | A kind of application of pyridazinone compound in oncotherapy |
JP7147444B2 (en) * | 2018-10-03 | 2022-10-05 | 株式会社島津製作所 | Sample injection device and sample injection system |
CN114560814B (en) * | 2022-03-02 | 2023-10-20 | 天津理工大学 | Synthesis method of substituted 2, 3-naphthyridine ketone compound |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4238490A (en) * | 1979-02-12 | 1980-12-09 | Diamond Shamrock Corporation | Antihypertensive pyridazin(2H)-3-ones |
BR8108745A (en) * | 1980-08-07 | 1982-07-06 | Diamond Shamrock Corp | DIFENYLPYRIDAZINONE HERBICIDES AND PLANT GROWTH REGULATORS |
US4404203A (en) * | 1981-05-14 | 1983-09-13 | Warner-Lambert Company | Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents |
WO1988009675A1 (en) * | 1987-06-05 | 1988-12-15 | Medicis Corporation | Inhibition of arachidonic acid metabolism |
AU691673B2 (en) * | 1994-11-14 | 1998-05-21 | Dow Agrosciences Llc | Pyridazinones and their use as fungicides |
US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
US6342510B1 (en) * | 1995-06-12 | 2002-01-29 | G. D. Searle & Co. | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist |
DE69825154T2 (en) * | 1997-03-14 | 2005-07-21 | Merck Frosst Canada & Co, Kirkland | PYRIDAZINONE AS INHIBITORS OF CYCLOOXYGENASE-2 |
-
1998
- 1998-08-10 PL PL98355418A patent/PL194175B1/en not_active IP Right Cessation
- 1998-08-10 CZ CZ20000446A patent/CZ300847B6/en not_active IP Right Cessation
- 1998-08-10 AU AU86976/98A patent/AU741317B2/en not_active Ceased
- 1998-08-10 JP JP2000507660A patent/JP2003516925A/en active Pending
- 1998-08-10 KR KR1020007001824A patent/KR100675028B1/en not_active IP Right Cessation
- 1998-08-10 HU HU0400909A patent/HUP0400909A3/en unknown
- 1998-08-10 TR TR2000/00478T patent/TR200000478T2/en unknown
- 1998-08-10 SK SK231-2000A patent/SK286972B6/en not_active IP Right Cessation
- 1998-08-10 IL IL13355298A patent/IL133552A/en not_active IP Right Cessation
- 1998-08-10 NZ NZ501808A patent/NZ501808A/en unknown
- 1998-08-10 CN CNB988083221A patent/CN1167687C/en not_active Expired - Fee Related
- 1998-08-24 AR ARP980104193A patent/AR015422A1/en active IP Right Grant
-
2000
- 2000-02-22 NO NO20000863A patent/NO315423B1/en not_active IP Right Cessation
- 2000-03-15 BG BG104241A patent/BG64675B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
BG104241A (en) | 2000-10-31 |
HUP0400909A2 (en) | 2004-07-28 |
NO20000863L (en) | 2000-02-22 |
IL133552A (en) | 2005-12-18 |
BG64675B1 (en) | 2005-11-30 |
SK286972B6 (en) | 2009-08-06 |
KR100675028B1 (en) | 2007-01-29 |
JP2003516925A (en) | 2003-05-20 |
PL355418A1 (en) | 2004-04-19 |
IL133552A0 (en) | 2001-04-30 |
CZ300847B6 (en) | 2009-08-26 |
KR20010023196A (en) | 2001-03-26 |
CN1277605A (en) | 2000-12-20 |
NZ501808A (en) | 2002-12-20 |
HUP0400909A3 (en) | 2004-10-28 |
AU8697698A (en) | 1999-03-16 |
TR200000478T2 (en) | 2002-04-22 |
SK2312000A3 (en) | 2001-02-12 |
AU741317B2 (en) | 2001-11-29 |
PL194175B1 (en) | 2007-05-31 |
NO315423B1 (en) | 2003-09-01 |
CN1167687C (en) | 2004-09-22 |
AR015422A1 (en) | 2001-05-02 |
CZ2000446A3 (en) | 2000-05-17 |
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |