NO20000860L - Cyclopeptide derivatives as adhesion inhibitors - Google Patents
Cyclopeptide derivatives as adhesion inhibitorsInfo
- Publication number
- NO20000860L NO20000860L NO20000860A NO20000860A NO20000860L NO 20000860 L NO20000860 L NO 20000860L NO 20000860 A NO20000860 A NO 20000860A NO 20000860 A NO20000860 A NO 20000860A NO 20000860 L NO20000860 L NO 20000860L
- Authority
- NO
- Norway
- Prior art keywords
- adhesion inhibitors
- cyclopeptide derivatives
- cyclopeptide
- derivatives
- arteriosclerosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Forbindelser med formel (I) hvor X, A, B og C har de i krav l angitte betydninger, samt deres salter, kan anvendes som integrininhibitorer, særlig til profylakse og behandling av sykdommer i blodomløpet, ved trombose, hjerteinfarkt, koronare hjertesykdommer, arteriosklerose, ved patologiske tilstander som underholdes eller propageres gjennom angiogenese og innen tumorterapien.Compounds of formula (I) wherein X, A, B and C have the meanings specified in claim 1, as well as their salts, can be used as integrin inhibitors, in particular for the prophylaxis and treatment of circulatory diseases, in thrombosis, heart attack, coronary heart disease, arteriosclerosis , in pathological conditions that are maintained or propagated through angiogenesis and within tumor therapy.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19736772A DE19736772A1 (en) | 1997-08-23 | 1997-08-23 | New guanidino-substituted bi:cyclic peptide compounds |
PCT/EP1998/005161 WO1999010371A2 (en) | 1997-08-23 | 1998-08-14 | Cyclopeptide derivatives as adhesion inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20000860D0 NO20000860D0 (en) | 2000-02-22 |
NO20000860L true NO20000860L (en) | 2000-02-22 |
Family
ID=7839977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20000860A NO20000860L (en) | 1997-08-23 | 2000-02-22 | Cyclopeptide derivatives as adhesion inhibitors |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1007545A2 (en) |
JP (1) | JP2001514186A (en) |
KR (1) | KR20010022828A (en) |
CN (1) | CN1267306A (en) |
AR (1) | AR013650A1 (en) |
AU (1) | AU734829B2 (en) |
BR (1) | BR9811992A (en) |
CA (1) | CA2301182A1 (en) |
DE (1) | DE19736772A1 (en) |
HU (1) | HUP0003500A3 (en) |
ID (1) | ID23952A (en) |
NO (1) | NO20000860L (en) |
PL (1) | PL341090A1 (en) |
RU (1) | RU2200166C2 (en) |
SK (1) | SK2132000A3 (en) |
TW (1) | TW477793B (en) |
WO (1) | WO1999010371A2 (en) |
ZA (1) | ZA987558B (en) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA43823C2 (en) * | 1992-07-06 | 2002-01-15 | Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг | PHARMACEUTICAL COMPOSITION FOR INTEGRIN INHIBITION <font face = "Symbol"> a </font> <sub> V </sub> <font face = "Symbol"> b </font> <sub> 3 </sub> cell adhesion mammal WAY treatment and prevention of diseases associated with cell adhesion DISORDERS, METHOD FOR BINDING LOCK integrin fibrinogen, a composition for wound healing |
DE4310643A1 (en) * | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclic adhesion inhibitors |
DE4415310A1 (en) * | 1994-04-30 | 1995-11-02 | Merck Patent Gmbh | Cyclopeptides |
JPH07316193A (en) * | 1994-05-24 | 1995-12-05 | Asahi Glass Co Ltd | Peptide derivative and use thereof |
-
1997
- 1997-08-23 DE DE19736772A patent/DE19736772A1/en not_active Withdrawn
-
1998
- 1998-08-14 KR KR1020007001430A patent/KR20010022828A/en not_active Application Discontinuation
- 1998-08-14 BR BR9811992-3A patent/BR9811992A/en not_active IP Right Cessation
- 1998-08-14 JP JP2000507697A patent/JP2001514186A/en active Pending
- 1998-08-14 CA CA002301182A patent/CA2301182A1/en not_active Abandoned
- 1998-08-14 WO PCT/EP1998/005161 patent/WO1999010371A2/en not_active Application Discontinuation
- 1998-08-14 EP EP98948833A patent/EP1007545A2/en not_active Withdrawn
- 1998-08-14 CN CN98808380A patent/CN1267306A/en active Pending
- 1998-08-14 ID IDW20000532A patent/ID23952A/en unknown
- 1998-08-14 RU RU2000107122/04A patent/RU2200166C2/en not_active IP Right Cessation
- 1998-08-14 HU HU0003500A patent/HUP0003500A3/en unknown
- 1998-08-14 AU AU95319/98A patent/AU734829B2/en not_active Ceased
- 1998-08-14 SK SK213-2000A patent/SK2132000A3/en unknown
- 1998-08-14 PL PL98341090A patent/PL341090A1/en unknown
- 1998-08-19 TW TW087113657A patent/TW477793B/en not_active IP Right Cessation
- 1998-08-20 ZA ZA987558A patent/ZA987558B/en unknown
- 1998-08-21 AR ARP980104136A patent/AR013650A1/en not_active Application Discontinuation
-
2000
- 2000-02-22 NO NO20000860A patent/NO20000860L/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2301182A1 (en) | 1999-03-04 |
WO1999010371A2 (en) | 1999-03-04 |
AU734829B2 (en) | 2001-06-21 |
WO1999010371A3 (en) | 1999-05-27 |
AU9531998A (en) | 1999-03-16 |
SK2132000A3 (en) | 2000-09-12 |
PL341090A1 (en) | 2001-03-26 |
EP1007545A2 (en) | 2000-06-14 |
TW477793B (en) | 2002-03-01 |
AR013650A1 (en) | 2001-01-10 |
NO20000860D0 (en) | 2000-02-22 |
HUP0003500A2 (en) | 2001-02-28 |
BR9811992A (en) | 2000-09-05 |
ZA987558B (en) | 1999-02-23 |
ID23952A (en) | 2000-06-08 |
RU2200166C2 (en) | 2003-03-10 |
CN1267306A (en) | 2000-09-20 |
KR20010022828A (en) | 2001-03-26 |
JP2001514186A (en) | 2001-09-11 |
DE19736772A1 (en) | 1999-02-25 |
HUP0003500A3 (en) | 2001-12-28 |
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