NO179247C - Non-ionic contrast compound and radiological preparation comprising it - Google Patents

Non-ionic contrast compound and radiological preparation comprising it

Info

Publication number
NO179247C
NO179247C NO902986A NO902986A NO179247C NO 179247 C NO179247 C NO 179247C NO 902986 A NO902986 A NO 902986A NO 902986 A NO902986 A NO 902986A NO 179247 C NO179247 C NO 179247C
Authority
NO
Norway
Prior art keywords
preparation
radiological
ionic contrast
contrast compound
compounds
Prior art date
Application number
NO902986A
Other languages
Norwegian (no)
Other versions
NO902986L (en
NO902986D0 (en
NO179247B (en
Inventor
Milos Sovak
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO902986D0 publication Critical patent/NO902986D0/en
Publication of NO902986L publication Critical patent/NO902986L/en
Publication of NO179247B publication Critical patent/NO179247B/en
Publication of NO179247C publication Critical patent/NO179247C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection

Abstract

Triiodo-5-aminoisophthalamides in which the amino and one of the amide nitrogen groups are substituted are indicated. The compounds have at least two hydroxyl groups and low viscosity and osmolality. Processes for the preparation of the compounds are indicated.
NO902986A 1989-07-05 1990-07-04 Non-ionic contrast compound and radiological preparation comprising it NO179247C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37571489A 1989-07-05 1989-07-05
US43152789A 1989-11-03 1989-11-03

Publications (4)

Publication Number Publication Date
NO902986D0 NO902986D0 (en) 1990-07-04
NO902986L NO902986L (en) 1991-01-07
NO179247B NO179247B (en) 1996-05-28
NO179247C true NO179247C (en) 1996-09-04

Family

ID=27007168

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902986A NO179247C (en) 1989-07-05 1990-07-04 Non-ionic contrast compound and radiological preparation comprising it

Country Status (16)

Country Link
EP (1) EP0406992B1 (en)
JP (1) JP3249112B2 (en)
AT (1) ATE119783T1 (en)
AU (1) AU643447B2 (en)
CA (1) CA2020489C (en)
CS (1) CS277109B6 (en)
DE (1) DE59008695D1 (en)
DK (1) DK0406992T3 (en)
ES (1) ES2069677T3 (en)
GR (1) GR3015580T3 (en)
HU (1) HU219585B (en)
IE (1) IE65719B1 (en)
IL (1) IL94718A (en)
NO (1) NO179247C (en)
PT (1) PT94595B (en)
RU (1) RU2060246C1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4109169A1 (en) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz WATER-SOLUBLE NON-IONIC X-RAY CONTRASTING AGENTS AND AGENTS AND METHOD FOR THE PRODUCTION THEREOF
DE4341472A1 (en) * 1993-12-02 1995-06-08 Schering Ag A method for increasing the stability of liposome suspensions containing hydrophilic drugs
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
DE19731591C2 (en) * 1997-07-17 1999-09-16 Schering Ag Pharmaceutical compositions containing triiodoaromatics containing perfluoroalkyl groups and their use in tumor therapy and interventional radiology
ITMI20010773A1 (en) * 2001-04-11 2002-10-11 Chemi Spa PROCESS FOR THE PRODUCTION OF HIGH PURITY IOEXOLO
EP2178568B1 (en) * 2007-07-12 2014-07-02 Ge Healthcare As Contrast agents
US8445725B2 (en) 2008-01-14 2013-05-21 Mallinckrodt Llc Process for the preparation of iosimenol
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
WO2011003894A1 (en) 2009-07-07 2011-01-13 Bracco Imaging Spa Process for the preparation of a iodinating agent
CA2881853A1 (en) 2012-09-27 2014-04-03 Ge Healthcare As Preparation of ioforminol, an x-ray contrast agent
JP7090645B2 (en) * 2017-05-01 2022-06-24 大塚製薬株式会社 Manufacturing method of iocimenol

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021481A (en) * 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
GB1538076A (en) * 1974-11-15 1979-01-10 Addressograph Multigraph Apparatus for electrostatic reprography
CH608189A5 (en) * 1974-12-13 1978-12-29 Savac Ag
FI760068A (en) * 1975-02-03 1976-08-04 Schering Ag
DE2926850C2 (en) * 1978-07-04 1985-01-24 Nyegaard & Co. A/S, Oslo A method for the preparation of a sterile injectable physiologically acceptable solution of a nonionic m-carboxamido-o-iodo-N - (β-hydroxyalkyl) aniline X-ray contrast agent and solutions of the X-ray contrast agent and a buffer
DE2909439A1 (en) * 1979-03-08 1980-09-18 Schering Ag NEW NON-ionic x-ray contrast agents
NL7905021A (en) * 1979-06-27 1980-12-30 Pielkenrood Vinitex Bv DEVICE FOR SEPARATING SUSPENDED COMPONENTS FROM A LIQUID.
DE3001292A1 (en) * 1980-01-11 1981-07-16 Schering Ag Berlin Und Bergkamen, 1000 Berlin NON-ionic 5-C SUBSTITUTED 2,4,6-TRIJOD ISOPHTHALIC ACID DERIVATIVES
DE3150916A1 (en) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-HYDROXYAETHYLATED 2,4,6-TRIJODAMINOISIOPHTHALIC ACID-BISTRIHYDROXYBUTYLAMIDES, THEIR PRODUCTION AND THEIR CONTAINING X-RAY CONTRASTING AGENTS "
DE3731542A1 (en) * 1987-09-17 1989-03-30 Schering Ag NEW DICARBONIC ACID-BIS (3,5-DICARBAMOYL-2,4,6-TRIIOD-ANILIDE), METHOD FOR THE PRODUCTION THEREOF AND THESE CONTAINING X-RAY AGENTS
DE3739098A1 (en) * 1987-11-16 1989-05-24 Schering Ag NEW SUBSTITUTED DICARBONIC ACID-BIS (3,5-DICARBAMOYL-2,4,6-TRIYOD ANILIDE), METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING X-RAY CONTRASTING AGENTS
EP0425482B1 (en) * 1988-07-20 1993-08-18 Novo Nordisk A/S Human insulin analogs and preparations containing them

Also Published As

Publication number Publication date
AU5869490A (en) 1991-01-10
CS335390A3 (en) 1992-01-15
EP0406992A3 (en) 1991-09-18
HUT57708A (en) 1991-12-30
NO902986L (en) 1991-01-07
NO902986D0 (en) 1990-07-04
IE902340A1 (en) 1991-01-16
IE65719B1 (en) 1995-11-15
PT94595B (en) 1997-02-28
HU219585B (en) 2001-05-28
NO179247B (en) 1996-05-28
AU643447B2 (en) 1993-11-18
CA2020489C (en) 2005-01-11
CA2020489A1 (en) 1991-01-06
PT94595A (en) 1991-03-20
IL94718A (en) 1994-10-21
DE59008695D1 (en) 1995-04-20
HU904104D0 (en) 1990-12-28
ATE119783T1 (en) 1995-04-15
RU2060246C1 (en) 1996-05-20
EP0406992A2 (en) 1991-01-09
EP0406992B1 (en) 1995-03-15
ES2069677T3 (en) 1995-05-16
CS277109B6 (en) 1992-11-18
GR3015580T3 (en) 1995-06-30
JP3249112B2 (en) 2002-01-21
IL94718A0 (en) 1991-04-15
JPH03115232A (en) 1991-05-16
DK0406992T3 (en) 1995-07-24

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Legal Events

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