NO177595C - Analogous Process for the Preparation of Therapeutically Eesters of Organic Acids and Alcohols Derived from 19-North Steroids - Google Patents

Analogous Process for the Preparation of Therapeutically Eesters of Organic Acids and Alcohols Derived from 19-North Steroids

Info

Publication number
NO177595C
NO177595C NO903475A NO903475A NO177595C NO 177595 C NO177595 C NO 177595C NO 903475 A NO903475 A NO 903475A NO 903475 A NO903475 A NO 903475A NO 177595 C NO177595 C NO 177595C
Authority
NO
Norway
Prior art keywords
denotes
radical
alkyl
hydrogen atom
optionally
Prior art date
Application number
NO903475A
Other languages
Norwegian (no)
Other versions
NO177595B (en
NO903475D0 (en
NO903475L (en
Inventor
Martine Moguilewsky
Lucien Nedelec
Francois Nique
Daniel Philibert
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NO903475D0 publication Critical patent/NO903475D0/en
Publication of NO903475L publication Critical patent/NO903475L/en
Priority to NO940954A priority Critical patent/NO177594C/en
Publication of NO177595B publication Critical patent/NO177595B/en
Publication of NO177595C publication Critical patent/NO177595C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Products of general formula (I): <IMAGE> in which R1 denotes an aliphatic hydrocarbon radical, R2 and R3, which are identical or different, denote a hydrogen atom or an alkyl radical, G denotes a hydrocarbon group containing from one to eighteen carbon atoms and optionally one or a number of identical or different heteroatoms, which is linked to the steroid nucleus by a carbon atom, and either X denotes XA, XA being a hydrogen atom, an alkyl radical, an arylalkyl radical or an acyl radical, and in this case Y denotes YA, YA being a group -B-O-CO-A-Z in which B denotes a saturated or unsaturated, linear or branched, divalent aliphatic radical, A denotes either a saturated or unsaturated, linear or branched, divalent aliphatic radical optionally interrupted or terminated by a divalent aromatic radical, or A denotes a divalent aromatic radical and Z denotes one of the functional groups -COOH or -SO3H, it being possible for these functional groups to be optionally converted into salt form or X denotes XB, XB being a group -CO-A-Z in which A and Z are as defined above and Y then denotes YB, YB being one of the groups chosen from -C IDENTICAL C-R4, -CH=CH-R4 or -CH2-CH2-R4, in which R4 denotes a hydrogen atom, a halogen atom, a trialkylsilyl radical, an alkyl radical or a phenyl radical, the said alkyl and phenyl radicals being optionally substituted.
NO903475A 1989-08-08 1990-08-07 Analogous Process for the Preparation of Therapeutically Eesters of Organic Acids and Alcohols Derived from 19-North Steroids NO177595C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO940954A NO177594C (en) 1989-08-08 1994-03-16 New esters of organic acids and alcohols derived from 19-nor-steroids, as well as preparations to prevent conception and abort pregnancy, containing the new esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8910648A FR2650748B1 (en) 1989-08-08 1989-08-08 NOVEL ESTERS OF ORGANIC ACIDS WITH ALCOHOLS DERIVED FROM 19-NOR STEROIDS AND THEIR SALTS, THEIR PREPARATION METHOD AND THE INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM

Publications (4)

Publication Number Publication Date
NO903475D0 NO903475D0 (en) 1990-08-07
NO903475L NO903475L (en) 1991-04-11
NO177595B NO177595B (en) 1995-07-10
NO177595C true NO177595C (en) 1995-10-18

Family

ID=9384560

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903475A NO177595C (en) 1989-08-08 1990-08-07 Analogous Process for the Preparation of Therapeutically Eesters of Organic Acids and Alcohols Derived from 19-North Steroids

Country Status (27)

Country Link
EP (1) EP0412907B1 (en)
JP (1) JP3056770B2 (en)
KR (1) KR910004648A (en)
CN (1) CN1036521C (en)
AT (1) ATE113958T1 (en)
AU (1) AU633604B2 (en)
CA (1) CA2022647A1 (en)
DE (1) DE69014012T2 (en)
DK (1) DK0412907T3 (en)
EG (1) EG19423A (en)
ES (1) ES2063940T3 (en)
FI (1) FI903905A0 (en)
FR (1) FR2650748B1 (en)
HU (1) HUT55031A (en)
IE (1) IE65905B1 (en)
IL (1) IL95272A (en)
MA (1) MA21925A1 (en)
MX (1) MX21771A (en)
NO (1) NO177595C (en)
NZ (1) NZ234824A (en)
OA (1) OA09303A (en)
PT (1) PT94935B (en)
RU (1) RU2056431C1 (en)
TN (1) TNSN90112A1 (en)
TW (1) TW201313B (en)
YU (1) YU47865B (en)
ZA (1) ZA905812B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659233B1 (en) * 1990-03-06 1994-01-21 Roussel Uclaf NEW USE OF ANTI-PROGESTOMIMETIC COMPOUNDS IN FARMING ANIMALS.
DE4434488A1 (en) * 1994-09-14 1996-03-21 Schering Ag Steroid esters and amides, processes for their preparation and their pharmaceutical use
AUPN058895A0 (en) * 1995-01-16 1995-02-09 Garvan Institute Of Medical Research Diagnostic method
US6090798A (en) * 1997-12-19 2000-07-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with glucocorticoid antagonists
DE19915871A1 (en) 1998-04-09 1999-10-21 Unisia Jecs Corp Viscous fluid coupling, for driving auxiliary units such as cooling fans
JP2000130165A (en) 1998-10-30 2000-05-09 Unisia Jecs Corp Fan coupling device
JP2001012511A (en) 1999-06-25 2001-01-16 Unisia Jecs Corp Fluid coupling
EP3541394A1 (en) * 2016-11-17 2019-09-25 Cytoo Skeletal muscle hypertrophy inducers
KR102518275B1 (en) * 2022-07-27 2023-04-05 주식회사 화성케미칼 Method of recycled neoprene fabric

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347126A1 (en) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11SS-ARYL-ESTRADIENE, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM
DE3506785A1 (en) * 1985-02-22 1986-08-28 Schering AG, Berlin und Bergkamen, 1000 Berlin 11SS-N, N-DIMETHYLAMINOPHENYL ESTRADIENE, THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE3878198T2 (en) * 1987-12-12 1993-06-24 Akzo Nv 11-ARYLSTEROID DERIVATIVES.
FR2643638B1 (en) * 1989-02-24 1991-06-14 Roussel Uclaf NOVEL 19-NOR STEROIDS HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE OR CARBAMATE FUNCTION, THEIR PREPARATION METHOD AND INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
PT94935A (en) 1991-04-18
JP3056770B2 (en) 2000-06-26
KR910004648A (en) 1991-03-29
HU904921D0 (en) 1991-01-28
CN1036521C (en) 1997-11-26
CA2022647A1 (en) 1991-02-09
ZA905812B (en) 1991-09-25
MX21771A (en) 1993-10-01
RU2056431C1 (en) 1996-03-20
YU47865B (en) 1996-02-19
TNSN90112A1 (en) 1991-03-05
IL95272A (en) 1996-01-31
TW201313B (en) 1993-03-01
JPH0377825A (en) 1991-04-03
FI903905A0 (en) 1990-08-07
NZ234824A (en) 1993-03-26
FR2650748B1 (en) 1991-11-08
DE69014012T2 (en) 1995-03-30
PT94935B (en) 1997-05-28
DK0412907T3 (en) 1995-04-03
ES2063940T3 (en) 1995-01-16
EP0412907A2 (en) 1991-02-13
MA21925A1 (en) 1991-04-01
YU151390A (en) 1992-12-21
DE69014012D1 (en) 1994-12-15
ATE113958T1 (en) 1994-11-15
AU6020890A (en) 1991-02-14
IE65905B1 (en) 1995-11-29
CN1049352A (en) 1991-02-20
FR2650748A1 (en) 1991-02-15
EP0412907A3 (en) 1991-07-24
AU633604B2 (en) 1993-02-04
IE902839A1 (en) 1991-02-27
EP0412907B1 (en) 1994-11-09
IL95272A0 (en) 1991-06-30
NO177595B (en) 1995-07-10
NO903475D0 (en) 1990-08-07
NO903475L (en) 1991-04-11
OA09303A (en) 1992-09-15
EG19423A (en) 1995-02-28
HUT55031A (en) 1991-04-29

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