NO177586B - Drug container - Google Patents
Drug container Download PDFInfo
- Publication number
- NO177586B NO177586B NO883494A NO883494A NO177586B NO 177586 B NO177586 B NO 177586B NO 883494 A NO883494 A NO 883494A NO 883494 A NO883494 A NO 883494A NO 177586 B NO177586 B NO 177586B
- Authority
- NO
- Norway
- Prior art keywords
- push
- container according
- seal
- package
- parts
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract description 15
- 229940079593 drug Drugs 0.000 title claims description 8
- 239000000853 adhesive Substances 0.000 claims description 7
- 230000001070 adhesive effect Effects 0.000 claims description 7
- 239000000262 estrogen Substances 0.000 description 2
- 229940011871 estrogen Drugs 0.000 description 2
- -1 ampoules Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000583 progesterone congener Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D5/00—Rigid or semi-rigid containers of polygonal cross-section, e.g. boxes, cartons or trays, formed by folding or erecting one or more blanks made of paper
- B65D5/42—Details of containers or of foldable or erectable container blanks
- B65D5/44—Integral, inserted or attached portions forming internal or external fittings
- B65D5/50—Internal supporting or protecting elements for contents
- B65D5/5002—Integral elements for containers having tubular body walls
- B65D5/5011—Integral elements for containers having tubular body walls formed by folding inwardly of extensions hinged to the upper or lower edges of the body
- B65D5/5014—Integral elements for containers having tubular body walls formed by folding inwardly of extensions hinged to the upper or lower edges of the body and with an integral end closure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
- B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Packages (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Centrifugal Separators (AREA)
- Mechanical Operated Clutches (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glass Compositions (AREA)
Abstract
Description
Oppfinnelsen vedrører en legemiddelbeholder, spesielt en slik for transdermale plastre og andre enkeltdosis-administreringsformer. The invention relates to a drug container, especially one for transdermal patches and other single-dose administration forms.
Transdermale plastre er som kjent administreringsformer som frigjør medikamenter langsomt og konstant gjennom huden. Et slikt kjent plaster som inneholder et østrogen er for eksempel omtalt i GE-A-2 093 694. Det gir østrogen trans-dermalt det leveren omgås, det vil si at "First-Pass"-effekten av levermetabolismen unngås. Fortrinnsvis bør pasienter som benytter slike plastre samtidig innta tabletter med et gestagen. For eksempel kan pasienten i en periode på 28 dager måtte bruke 8 plastre og 12 tabletter. Når tabletter og plastre leveres, er det vanskelig å huske og å vite når et nytt plaster og når en tablett må inntas. Transdermal patches are known forms of administration that release drugs slowly and constantly through the skin. Such a known patch containing an estrogen is for example described in GE-A-2 093 694. It provides estrogen transdermally which bypasses the liver, i.e. the "First-Pass" effect of liver metabolism is avoided. Preferably, patients who use such patches should simultaneously take tablets with a progestogen. For example, in a period of 28 days the patient may have to use 8 plasters and 12 tablets. When tablets and patches are delivered, it is difficult to remember and to know when a new patch and when a tablet must be taken.
Ved oppfinnelsen skal det skaffes en beholder som for pasienten letter sikringen av den "synkrone" behandling med plastre og inntak av for eksempel tabletter. With the invention, a container is to be provided which makes it easier for the patient to ensure the "synchronous" treatment with plasters and the ingestion of, for example, tablets.
Denne oppgave løses ifølge oppfinnelsen ved en legemiddelbeholder, utformet som en eske som har en lukkbar lomme for opptak av et antall små artikler, for eksempel legemidler, idet lommen er lukkbar med et klapp-lokk og som har plass nok for en gjennomtrykkspakning med enkeltdoser av et legemiddel, og denne legemiddelbeholder karakteriseres ved at gjennomtrykkspakningen er festbar til en med klapp-lokket forbundet og innover foldbar del på en slik måte at enkeltdosene lett kan fjernes fra gjennomtrykkspakningen. According to the invention, this task is solved by a medicine container, designed as a box which has a closable pocket for receiving a number of small articles, for example medicines, the pocket being closable with a flap lid and which has enough space for a push-through package with single doses of a medicine, and this medicine container is characterized by the push-through package being attachable to a part connected to the flap lid and foldable inwards in such a way that the individual doses can be easily removed from the push-through package.
Foruten tabletter menes med enkeltdose-administreringsformer blant annet kapsler av hard eller fleksibel gelatin, ampuller, tapper og så videre. In addition to tablets, single-dose administration forms include hard or flexible gelatin capsules, ampoules, drops and so on.
Et utall av blisterpakninger eller poser er omtalt i patentskriftene GE-A-689 631, DE-A-1 803 236, TJS-A-1 474 248, DE-A-2 516 720, DE-A-2 714 420, CE-A-516 450 og EP-A-210 820. Ingen av disse patenter åpenbarer kombinasjonen av en blisterpakning med en lomme for transdermale plastre. A number of blister packs or bags are described in the patent documents GE-A-689 631, DE-A-1 803 236, TJS-A-1 474 248, DE-A-2 516 720, DE-A-2 714 420, CE -A-516 450 and EP-A-210 820. Neither of these patents discloses the combination of a blister pack with a pocket for transdermal patches.
I patentskriftene GB-A-1 236 675, GB-A-1 086 653, GB-A-974 179, GB-A-467 606, US-A-4 664 262, US-A 3 743 084 og US-A-3 567 013 omtales forskjellige beholdere for tabletter. Ingen av disse patenter åpenbarer imidlertid en adskilt lomme for transdermale plastre. Ingen av de i de nevnte patenter åpenbarte beholdere synes samtidig å kunne inneholde transdermale plastre og tabletter. Bunndelen av beholderen i US-patent 4 664 262 kan muligens inneholde plastre, men det finnes ingen måte for å ta disse ut igjen. In the patents GB-A-1 236 675, GB-A-1 086 653, GB-A-974 179, GB-A-467 606, US-A-4 664 262, US-A 3 743 084 and US-A -3 567 013 mentions different containers for tablets. However, none of these patents discloses a separate pocket for transdermal patches. None of the containers disclosed in the aforementioned patents seem to be able to contain transdermal patches and tablets at the same time. The bottom of the container in US patent 4,664,262 may possibly contain plasters, but there is no way to take them out again.
Oppfinnelsen skal i det følgende forklares ved hjelp av et på tegningen vist utførelseseksempel i form av en eske. In the following, the invention will be explained with the help of an embodiment shown in the drawing in the form of a box.
Fig. la viser et emne for esken i utbrettet tilstand, Fig. la shows a blank for the box in the unfolded state,
fig. lb viser perspektivisk en gjennomtrykkpakning, fig. lb shows in perspective a push-through gasket,
fig. 2 viser perspektivisk den åpne eske og fig. 2 shows the open box in perspective and
fig. 3 viser perspektivisk den lukkede eske. fig. 3 shows the closed box in perspective.
Esken på fig. 2 og 3 dannes av det på fig. la viste emne og den på fig. lb viste gjennomtrykkspakning. Herved brettes emnet rundt de med strekpunkterte linjer antydede falser. The box in fig. 2 and 3 are formed from that in fig. la shown subject and the one in fig. lb showed pressure seal. In this way, the workpiece is folded around the folds indicated by dotted lines.
Før sammenbretting av delene 32 og 34 rundt brettelinjen 33 legges gj ennomtrykkspakningen 41 inn som vist på fig. lb. Hullene 35 av delene 32 og 34 er speilbildeaktig til hverandre. Tablettbeholderen 42 har et med hullene 35 dekningslikt mønster slik at tablettbeholderene og dermed tablettene kan settes nøyaktig i hullene 35. Efter sammenbretting klebes eller sveises feltene 32 og 34 til hverandre henholdsvis med den meilomlagte gjennomtrykkspakning 41 alt efter materiale (kartong eller plast). Det kan også velges mellom løsbar klebe- og/eller stikkforbindelse, hvilket muliggjør en utveksling henholdsvis erstatning av den (forbrukte) gjennomtrykkspakning. Pakningen kan da anvendes for flere behandlingscykler. For fremstilling av løsbare klebeforbindelser anvendes klebestoffer som på den ene side bare gir en begrenset klebekraft og på den annen side muliggjør en flere gangers løsning og sammenklebing av delene. Before folding the parts 32 and 34 around the fold line 33, the compression seal 41 is inserted as shown in fig. lb. The holes 35 of the parts 32 and 34 are mirror images of each other. The tablet container 42 has a pattern similar to that of the holes 35, so that the tablet containers and thus the tablets can be placed exactly in the holes 35. After folding, the fields 32 and 34 are glued or welded to each other, respectively, with the overlapped pressure seal 41, depending on the material (cardboard or plastic). It is also possible to choose between a removable adhesive and/or plug-in connection, which enables an exchange or replacement of the (consumed) push-through gasket. The pack can then be used for several treatment cycles. For the production of releasable adhesive compounds, adhesives are used which, on the one hand, only provide a limited adhesive force and, on the other hand, enable the parts to be loosened and glued together several times.
Feltene 12 og 14 danner for- og bakvegg den ferdige eske for lommen 10, feltene 16 og 18 danner hver en sidevegg, feltet 20 danner bunnen og feltene 23 og 36 danner lukkelokket. Feltene 22, 24, 26 og 28 danner forbindingslasker. Feltet 38 danner en stikklask. Fields 12 and 14 form the front and back walls of the finished box for the pocket 10, fields 16 and 18 each form a side wall, field 20 forms the bottom and fields 23 and 36 form the closing lid. Fields 22, 24, 26 and 28 form dressing flaps. The field 38 forms a slot.
Til forming av lommen 10 brettes først laskene 24 og 26 på sideveggfeltene 16 og 18. Derefter gjennomføres brettinger rundt de tilsvarende falser respektivt i vinkel på 90° To form the pocket 10, the flaps 24 and 26 are first folded on the side wall panels 16 and 18. Then folds are carried out around the corresponding folds respectively at an angle of 90°
(loddrett til emnets plan) oppad i rekkefølge lask 28 -bunn 20 - lask 22 - sidevegg 18 - fremvegg 14 - sidevegg 16. (perpendicular to the plane of the workpiece) upwards in order lask 28 - bottom 20 - lask 22 - side wall 18 - front wall 14 - side wall 16.
Laskene 28 og 22 kommer derved til å ligge på baksiden og klebes eller sveises sammen med denne. De to lasker 24 og 26 i lommen 10 kan nå trykkes mot bunnen 20. De hindrer at det danner seg en spalte mellom sideveggene 16, 18 og bunnen 20. The flaps 28 and 22 will thereby lie on the back and be glued or welded together with it. The two flaps 24 and 26 in the pocket 10 can now be pressed against the base 20. They prevent a gap from forming between the side walls 16, 18 and the base 20.
Lommen 10 lukkes ved at delen 30 med tablettbeholderen 42 The pocket 10 is closed by the part 30 with the tablet container 42
brettes mot lokket 36 og dette derefter brettes 180°C nedad. I denne stilling er lokket sikret mot utilsiktet åpning ved innskyving av stikklasken 38 i slissen 40 i en lukkestilling. is folded towards the lid 36 and this is then folded 180°C downwards. In this position, the lid is secured against accidental opening by pushing the plug 38 into the slot 40 in a closed position.
Lommen 10 opptar antallet av plastre som er nødvendig for en behandlingscyklus, samt en vedlagt pakkeseddel med alle nødvendige angivelser over medikamentene samt deres inntak. Lokket 36 kan i tillegg påtrykkes inntakshenvisninger i kort form eller inneholde ved hjelp av en påklebet etikett som letter pasienten synkroniseringen av inntak av medikamentene, når for eksempel et plaster skal anvendes og når en tablett skal inntas. Denne type forbindelse av informasjon og beholder har den fordel at den ikke kan gå tapt. Tilleggs-opplysninger som for eksempel 1. dag og 2. dag osv. kan også være påtrykt på den gjennomtrykkspakningbærende del 30 tilordnet tablettbeholderene 12. The pocket 10 holds the number of plasters that are necessary for a treatment cycle, as well as an attached packing slip with all necessary information about the drugs and their intake. The lid 36 can also be printed with instructions for intake in short form or contain, by means of an attached label, which makes it easier for the patient to synchronize the intake of the medication, when, for example, a patch is to be used and when a tablet is to be taken. This type of connection of information and container has the advantage that it cannot be lost. Additional information such as, for example, 1st day and 2nd day etc. can also be printed on the push-through seal bearing part 30 assigned to the tablet containers 12.
Det viste utførelseseksempel på en legemiddelbeholder ifølge oppfinnelsen er bare en mulig utførelsesform av oppfinnelsen. Mange andre utførelsesformer er mulig. Vesentlig er at beholderen samtidig inneholder to plasser for to forskjellige typer administreringsformer, på den ene side for eksempel side transdermale plastre og på den annen side for eksempel tabletter. Hvis beholderen er utformet som eske, kan selvsagt også andre "emner" velges enn den på fig.la. The shown embodiment of a medicine container according to the invention is only one possible embodiment of the invention. Many other embodiments are possible. It is essential that the container simultaneously contains two spaces for two different types of administration forms, on one side for example transdermal patches and on the other side for example tablets. If the container is designed as a box, other "subjects" can of course also be selected than the one in fig.1a.
Claims (8)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878718797A GB8718797D0 (en) | 1987-08-07 | 1987-08-07 | Container |
Publications (4)
Publication Number | Publication Date |
---|---|
NO883494D0 NO883494D0 (en) | 1988-08-05 |
NO883494L NO883494L (en) | 1989-02-08 |
NO177586B true NO177586B (en) | 1995-07-10 |
NO177586C NO177586C (en) | 1995-10-18 |
Family
ID=10621998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO883494A NO177586C (en) | 1987-08-07 | 1988-08-05 | Drug container |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0307352B1 (en) |
JP (1) | JP2791477B2 (en) |
AT (1) | ATE104540T1 (en) |
AU (1) | AU626267B2 (en) |
CA (1) | CA1331167C (en) |
DE (1) | DE3889178D1 (en) |
DK (1) | DK173959B1 (en) |
ES (1) | ES2051313T3 (en) |
FI (1) | FI92679C (en) |
GB (1) | GB8718797D0 (en) |
NO (1) | NO177586C (en) |
NZ (1) | NZ225699A (en) |
PT (2) | PT88163A (en) |
ZA (1) | ZA885770B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2256853B (en) * | 1991-06-20 | 1994-10-12 | Imp Pharmaceutical Services Li | A packaging device for blister packaged pills |
JPH0556141U (en) * | 1991-12-27 | 1993-07-27 | 大日本製薬株式会社 | Drug holder |
JPH0633935Y2 (en) * | 1992-03-27 | 1994-09-07 | サカセ化学工業株式会社 | Grouping Medicine Pool |
DE4429503C2 (en) * | 1994-08-19 | 2003-09-18 | Astrazeneca Ab | Package, especially pharmaceutical package |
EP0725015A1 (en) * | 1995-02-04 | 1996-08-07 | BIOMEDICA ARZNEIMITTEL GmbH & Co. KG | Package for tablets contained in a blister pack |
DE19831263A1 (en) * | 1998-07-11 | 2000-01-13 | Lohmann Therapie Syst Lts | Pharmaceutical form |
DE19855318C1 (en) * | 1998-12-01 | 2000-04-20 | Lohmann Therapie Syst Lts | Packaging unit for two different medicaments for joint use comprises an additional foldable flap element with rows of holes for accommodation capsules in blister packages |
JP4802404B2 (en) * | 2001-06-26 | 2011-10-26 | 凸版印刷株式会社 | Portable drug folder |
WO2003010066A1 (en) * | 2001-07-26 | 2003-02-06 | Novo Nordisk A/S | A package for blister pack strips and a blank for the manufacturing of a package |
JPWO2004090955A1 (en) * | 2003-04-04 | 2006-07-06 | 株式会社ニコン | Illumination optical apparatus, projection exposure apparatus, and exposure method |
EP1481913A1 (en) | 2003-05-26 | 2004-12-01 | Dividella AG | Child-resistant package |
ITMI20042194A1 (en) * | 2004-11-16 | 2005-02-16 | Gi Bi Effe Srl | DEVICE FOR SELECTIVE DELIVERY OF SOLID PRODUCTS FROM A BLISTER HOLDED BY THE SAME DEVICE |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1474248A (en) * | 1922-03-29 | 1923-11-13 | English Arthur | Container for coloring-agent capsules |
GB689631A (en) * | 1950-02-10 | 1953-04-01 | Rose Brothers Ltd | Improvements in cartons, boxes and like containers |
DE1803236A1 (en) * | 1968-10-11 | 1970-05-14 | Arne Larsson | Box for gifts, preferably for confectionery |
CH516450A (en) * | 1970-10-20 | 1971-12-15 | Buergi Xaver | Packaging for tablets or pills |
DE2516720A1 (en) * | 1975-04-16 | 1976-10-28 | Braun Ag | Small goods twin section packaging unit - one sections containing the goods and the other in pull out form, used for contents information |
DE2714420A1 (en) * | 1976-06-01 | 1977-12-08 | Int Pregnancy Advisory Service | Contraceptive compsns. contg. gestagens - for admin. to both male and female |
JPS6190718U (en) * | 1984-11-16 | 1986-06-12 | ||
GB8518828D0 (en) * | 1985-07-25 | 1985-08-29 | American Home Prod | Tablet package |
JPS643638U (en) * | 1987-06-27 | 1989-01-11 |
-
1987
- 1987-08-07 GB GB878718797A patent/GB8718797D0/en active Pending
-
1988
- 1988-07-29 ES ES88810523T patent/ES2051313T3/en not_active Expired - Lifetime
- 1988-07-29 DE DE3889178T patent/DE3889178D1/en not_active Expired - Fee Related
- 1988-07-29 EP EP88810523A patent/EP0307352B1/en not_active Expired - Lifetime
- 1988-07-29 AT AT8888810523T patent/ATE104540T1/en not_active IP Right Cessation
- 1988-08-01 PT PT88163A patent/PT88163A/en active IP Right Grant
- 1988-08-05 ZA ZA885770A patent/ZA885770B/en unknown
- 1988-08-05 AU AU20430/88A patent/AU626267B2/en not_active Ceased
- 1988-08-05 NO NO883494A patent/NO177586C/en unknown
- 1988-08-05 NZ NZ225699A patent/NZ225699A/en unknown
- 1988-08-05 FI FI883657A patent/FI92679C/en not_active IP Right Cessation
- 1988-08-05 DK DK198804392A patent/DK173959B1/en not_active IP Right Cessation
- 1988-08-05 CA CA000573948A patent/CA1331167C/en not_active Expired - Fee Related
- 1988-08-08 JP JP63197797A patent/JP2791477B2/en not_active Expired - Fee Related
-
1993
- 1993-08-06 PT PT8859U patent/PT8859T/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0307352B1 (en) | 1994-04-20 |
DK439288D0 (en) | 1988-08-05 |
NO883494D0 (en) | 1988-08-05 |
GB8718797D0 (en) | 1987-09-16 |
NO177586C (en) | 1995-10-18 |
PT88163A (en) | 1989-06-30 |
NO883494L (en) | 1989-02-08 |
DE3889178D1 (en) | 1994-05-26 |
AU626267B2 (en) | 1992-07-30 |
FI883657A0 (en) | 1988-08-05 |
DK173959B1 (en) | 2002-03-11 |
CA1331167C (en) | 1994-08-02 |
ZA885770B (en) | 1989-03-29 |
FI92679C (en) | 1994-12-27 |
EP0307352A1 (en) | 1989-03-15 |
NZ225699A (en) | 1990-06-26 |
ATE104540T1 (en) | 1994-05-15 |
AU2043088A (en) | 1989-02-09 |
JP2791477B2 (en) | 1998-08-27 |
JPS6470058A (en) | 1989-03-15 |
FI92679B (en) | 1994-09-15 |
PT8859T (en) | 1994-02-28 |
FI883657A (en) | 1989-02-08 |
ES2051313T3 (en) | 1994-06-16 |
DK439288A (en) | 1989-02-08 |
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