NO174386C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloheksanacetamidderivater - Google Patents

Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloheksanacetamidderivater

Info

Publication number
NO174386C
NO174386C NO900234A NO900234A NO174386C NO 174386 C NO174386 C NO 174386C NO 900234 A NO900234 A NO 900234A NO 900234 A NO900234 A NO 900234A NO 174386 C NO174386 C NO 174386C
Authority
NO
Norway
Prior art keywords
lower alkyl
aryl
hydrogen
preparation
therapeutically active
Prior art date
Application number
NO900234A
Other languages
English (en)
Norwegian (no)
Other versions
NO900234D0 (no
NO900234L (no
NO174386B (no
Inventor
Gary Lee Olson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO900234D0 publication Critical patent/NO900234D0/no
Publication of NO900234L publication Critical patent/NO900234L/no
Publication of NO174386B publication Critical patent/NO174386B/no
Publication of NO174386C publication Critical patent/NO174386C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
NO900234A 1989-01-17 1990-01-16 Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloheksanacetamidderivater NO174386C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29772689A 1989-01-17 1989-01-17
US37764389A 1989-07-10 1989-07-10

Publications (4)

Publication Number Publication Date
NO900234D0 NO900234D0 (no) 1990-01-16
NO900234L NO900234L (no) 1990-07-18
NO174386B NO174386B (no) 1994-01-17
NO174386C true NO174386C (no) 1994-04-27

Family

ID=26970288

Family Applications (1)

Application Number Title Priority Date Filing Date
NO900234A NO174386C (no) 1989-01-17 1990-01-16 Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloheksanacetamidderivater

Country Status (16)

Country Link
EP (1) EP0381959B1 (de)
JP (1) JPH02229154A (de)
KR (1) KR900011759A (de)
AT (1) ATE122037T1 (de)
AU (1) AU625157B2 (de)
CA (1) CA2007732A1 (de)
DE (1) DE69019007T2 (de)
DK (1) DK0381959T3 (de)
ES (1) ES2071685T3 (de)
FI (1) FI900231A7 (de)
HU (1) HUT53607A (de)
IL (1) IL93051A0 (de)
MC (1) MC2081A1 (de)
NO (1) NO174386C (de)
NZ (1) NZ232112A (de)
PT (1) PT92874A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4404848A1 (de) * 1994-02-16 1995-08-17 Hoechst Ag Substituierte Cyclohexanolester, ihre Verwendung zur Behandlung von Krankheiten und pharmazeutische Präparate
KR100395779B1 (ko) * 2001-05-25 2003-08-21 한국화학연구원 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법
EP3260118B1 (de) 2008-10-16 2021-03-24 The Johns Hopkins University Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2968220B1 (de) 2013-03-15 2021-05-05 Agenebio, Inc. Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa

Also Published As

Publication number Publication date
JPH02229154A (ja) 1990-09-11
AU625157B2 (en) 1992-07-02
NO900234D0 (no) 1990-01-16
NO900234L (no) 1990-07-18
EP0381959B1 (de) 1995-05-03
DE69019007D1 (de) 1995-06-08
EP0381959A1 (de) 1990-08-16
FI900231A7 (fi) 1990-07-18
PT92874A (pt) 1990-07-31
CA2007732A1 (en) 1990-07-17
ES2071685T3 (es) 1995-07-01
NO174386B (no) 1994-01-17
AU4798890A (en) 1990-07-26
ATE122037T1 (de) 1995-05-15
HUT53607A (en) 1990-11-28
DE69019007T2 (de) 1995-09-14
HU900127D0 (en) 1990-03-28
MC2081A1 (fr) 1991-01-07
NZ232112A (en) 1992-07-28
IL93051A0 (en) 1990-11-05
KR900011759A (ko) 1990-08-02
FI900231A0 (fi) 1990-01-16
DK0381959T3 (da) 1995-09-04

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